Abstract: The present invention relates to a compound of formula (1) or a pharmaceutically acceptable salt or solvate thereof, wherein Y3 is O or S, wherein s, t, u and w are, independently of each other, 0 or 1, wherein i is an integer of from 1 to 3, wherein j is an integer of from 3 to 5, and wherein Z1, Z2 and Z3 are independently of each other, selected from the group consisting of CO2H, —SO2H, —SO3H, —OSO3H, and —OPO3H2, R1 is —CH3 or H, preferably H, X is selected from the group consisting of alkylaryl, aryl, alkylheteroaryl and heteroaryl, Y1 and Y2 are independently, of each other, selected from the group consisting of aryl, alkylaryl, cycloalkyl, heterocycloalkyl, heteroaryl and alkylheteroaryl, and wherein A is a chelator residue having a structure selected from the group consisting of (Ia), (Ib) and (Ic) wherein R2, R3, R4 and R5 are, independently of each other, selected from the group consisting of H, —CH2—COOH and —CH2—C(?O)—NH2 or wherein R2 and R4 form a —(CH2)n— bridge with n being an integer

Abstract: The disclosure relates to an assembly comprising a component rotatable about a rotary axis for an actuating drive comprising a sensor element attached to the rotatable component. The rotatable component has a support surface from which a fixing element protrudes in parallel to the rotary axis. The sensor element includes an opening. The sensor element is arranged on the support surface in such a manner that the fixing element penetrates the opening. A surface of the sensor element adjacent to the opening has a structure. A top portion of the fixing element is in interlocking engagement with the structure so that the attached sensor element is connected to the component in a torque-resistant manner.

Abstract: A rotor for an electric motor, comprising a rotor magnet and a bearing for the rotatable support on a fixed axle, the bearing comprising first and second bearing half-shells, wherein at least the first bearing half-shell is moveably arranged within the rotor body with respect to the second bearing half-shell, and wherein the first bearing half-shell is supported against the rotor body by a resilient element tangentially arranged with respect to the axle. The resilient element, at both its side surfaces facing in an axial direction of the axle, has at least one respective first protrusion extending in the axial direction, and the first bearing half-shell, on a side facing away from its bearing surface, includes at least two axially spaced second protrusions each extending in a radial direction and cooperating with the first protrusions for aligning the resilient element.

Abstract: The present disclosure relates to a method of inducing a neuroprotective state comprising administering a Bromodomain and Extra-Terminal motif (BET) inhibitor under conditions effective to induce a neuroprotective state. Also disclosed are methods of preventing and/or treating neurodegenerative disease, methods of reducing microglial inflammation, and methods of restoring microglial homeostasis, where the methods include administering a Bromodomain and Extra-Terminal motif (BET) inhibitor.

Abstract: The disclosure relates to an assembly comprising a component rotatable about a rotary axis for an actuating drive comprising a sensor element attached to the rotatable component. The rotatable component has a support surface from which a fixing element protrudes in parallel to the rotary axis. The sensor element includes an opening. The sensor element is arranged on the support surface in such a manner that the fixing element penetrates the opening. A surface of the sensor element adjacent to the opening has a structure. A top portion of the fixing element is in interlocking engagement with the structure so that the attached sensor element is connected to the component in a torque-resistant manner.

Abstract: The present invention relates to an aroma mixture or a foodstuff comprising an ionone or a related compound as well as an alkylated 1,4-pyrazine. Hereby, the unpleasant taste and odor of biogenic amines can be reduced.

Abstract: A rotor for an electric motor, comprising a rotor magnet and a bearing for the rotatable support on a fixed axle, the bearing comprising first and second bearing half-shells, wherein at least the first bearing half-shell is moveably arranged within the rotor body with respect to the second bearing half-shell, and wherein the first bearing half-shell is supported against the rotor body by a resilient element tangentially arranged with respect to the axle. The resilient element, at both its side surfaces facing in an axial direction of the axle, has at least one respective first protrusion extending in the axial direction, and the first bearing half-shell, on a side facing away from its bearing surface, includes at least two axially spaced second protrusions each extending in a radial direction and cooperating with the first protrusions for aligning the resilient element.

Abstract: Suggested is a mixture of matter, comprising: (a) steviol glycosides, (b) starch degradation products and (c) one or more phenolic sweetness-enhancing aroma substances selected from the group formed by hesperetin, phloretin, 1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one, 7,3-dihydroxy-4?-methoxyflavan and 5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2-chromanone. On condition that components (a+b) and (c) are present in a ratio by weight of from 1.

Abstract: A lubricating nipple (1) to be pressed into a bore (5) of a bearing bush (7) of a universal joint has a housing with a flow-through channel (22) to receive a lubricant. A check valve (25, 26, 27) is arranged in the through-flow channel (22). A seat portion (3) positions the lubricating nipple (1) in the bore (5) in the mounted condition. A coupling portion (2) couples the lubricating nipple (1) to a lubricating device. The coupling portion (2) has a first abutment face (10) that faces the seat portion (3). The mounted lubricating nipple (1), in the pressing-in direction, is axially supported by the first abutment face (10) against the thin-walled component (7). A collar portion (4) has a second abutment face (12). The second abutment face (12) is arranged opposite to the first abutment face (10). The mounted lubricant nipple (1) can be axially supported by the second abutment face (12) against the thin-walled component (7).

Abstract: The present application relates to a use of a compound of Formula I or of a mixture of compounds of Formula I: wherein R1 to R10 each independently of one another represent H, methoxy or ethoxy and at least one of the radicals R1 to R10 represents methoxy or ethoxy to intensify the sensory impression of alcohol.

Abstract: An apparatus for distributing liquids to one or more receiving elements. The apparatus comprises a first element arrangement having one or more first receiving elements, a second element arrangement having one or more second receiving elements, a distributor adapted for distributing liquids to the first receiving elements, and an adapter adapted for transferring the liquids from the first receiving elements to the second receiving elements.

Abstract: An apparatus for distributing liquids to one or more receiving elements. The apparatus comprises a first element arrangement having one or more first receiving elements, a second element arrangement having one or more second receiving elements, a distributor adapted for distributing liquids to the first receiving elements, and an adapter adapted for transferring the liquids from the first receiving elements to the second receiving elements.

Abstract: A drive system for a transportation device having an electric machine. The electric machine has a converter unit and a cooling unit with the converter unit being embodied at least partially in the shape of a ring and surrounding the electric machine or components of the electric machine.

Abstract: A drive system for a transportation device having an electric machine. The electric machine has a converter unit and a cooling unit with the converter unit being embodied at least partially in the shape of a ring and surrounding the electric machine or components of the electric machine.

Abstract: A control for a drive reel partitions the reel into a plurality of angle-of-rotation segments. Compensation signals are produced by detecting deviations from a selected parameter at each of said segments. The compensation signals result from subjecting the deviations to integration wherein a plurality of integrators are included for this purpose, one for each of the segments.