Abstract: The invention relates to a nebulizer (1) comprising an aerosol generator (6), a nebulizing chamber (5) and an outlet (16), the aerosol generator (6) being designed to release an aerosol into the nebulizing chamber (5) and the outlet (16) being designed to allow the removal of the aerosol from the nebulizing chamber (5). To achieve a high output rate, a wetting surface (2) is provided in the nebulizing chamber (5).

Abstract: The invention relates to a nebulizer comprising an aerosol generator, a nebulizing chamber and an outlet, the aerosol generator being designed to release an aerosol into the nebulizing chamber and the outlet being designed to allow the removal of the aerosol from the nebulizing chamber. To achieve a high output rate, a wetting surface is provided in the nebulizing chamber.

Abstract: Method of generating an aerosol by means of an inhalation device for inhalation by a human or animal body, the method comprising providing liquid in the inhalation device, chemically generating gas bubbles in the liquid, bursting of the gas bubbles at the surface of the liquid, thereby generating an aerosol.

Abstract: A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterised in that it exhibits a low effective flow rate of less than about 5 liters per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Abstract: The invention relates to a nebulizer (1) comprising an aerosol generator (6), a nebulizing chamber (5) and an outlet (16), the aerosol generator (6) being designed to release an aerosol into the nebulizing chamber (5) and the outlet (16) being designed to allow the removal of the aerosol from the nebulizing chamber (5). To achieve a high output rate, a wetting surface (2) is provided in the nebulizing chamber (5).

Abstract: In a first aspect, the invention relates to a method for operating an aerosol inhalation device (10), comprising the steps of transporting a certain amount of an aerosol to a desired location outside said device (10) and vibrating the transported aerosol when it has reached said desired location. In a second aspect, the invention relates to an aerosol inhalation device (10) comprising a pump (1) for flowing a certain amount of an aerosol to a desired location outside the device (10), a vibrator (2) for vibrating the transported aerosol in a vibration mode and a control configured to actuate the vibrator (2) for vibrating the flowed aerosol only when it has reached said desired location.

Abstract: The invention relates to an aerosol delivery device (10, 100, 100?) comprising an aerosol generator (12, 106) for generating an aerosol in the device and a fluid conveying unit (14, 16, 18; 102, 104, 130) configured to induce a first fluid flow (26, 120) having a first flow rate in the device for transporting at least a portion of the generated aerosol outside the device and to induce a second fluid flow (32, 122) having a second flow rate in the device for conveying a fluid into the device, wherein the fluid conveying unit comprises a vibrator (18, 104) for vibrating the aerosol and the first flow rate is equal to or smaller than the second flow rate.

Abstract: A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterised in that it exhibits a low effective flow rate of less than about 5 litres per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Abstract: A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterized in that it exhibits a low effective flow rate of less than about 5 liters per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Abstract: The invention relates to a method for operating an aerosol delivery device (10), comprising the steps of generating a predetermined amount of an aerosol in the device (10) and inducing a transport flow in the device (10) for transporting at least a portion of the predetermined amount of the aerosol outside the device (10). During the aerosol generating step, the transport flow is first induced, then stopped after a predetermined first period of time and then induced again after a predetermined second period of time.

Abstract: Aerosol therapy device comprising a nebuliser (10) for generating an aerosol and forming an aerosol flow, a first nosepiece (11) for introducing the aerosol flow into one of the two nostrils (12) of a user, a pressure fluctuation source for generating a pressure fluctuation (DS), a second nosepiece (14) for introducing the pressure fluctuation into the other of the two nostrils (15) of the user in order to superimpose the pressure fluctuation and the aerosol flow, and a sensor system comprising a first pressure sensor (19) for detecting the signal of the pressure fluctuation that arrives at the first nosepiece (11), and an evaluation means (18) that concludes the degree of closure of the velum of the user based on the signal.

Abstract: A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterised in that it exhibits a low effective flow rate of less than about 5 litres per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.

Abstract: Aerosol therapy device comprising a nebuliser (10) for generating an aerosol and forming an aerosol flow, a first nosepiece (11) for introducing the aerosol flow into one of the two nostrils (12) of a user, a pressure fluctuation source for generating a pressure fluctuation (DS), a second nosepiece (14) for introducing the pressure fluctuation into the other of the two nostrils (15) of the user in order to superimpose the pressure fluctuation and the aerosol flow, and a sensor system comprising a first pressure sensor (19) for detecting the signal of the pressure fluctuation that arrives at the first nosepiece (11), and an evaluation means (18) that concludes the degree of closure of the velum of the user based on the signal.

Abstract: A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nasal cavity or of the paranasal sinuses. The aerosol is characterised in that its pressure is not constant, but pulsates at a frequency of about 10 to 90 Hz. The mass median diameter of the dispersed phase is from about 2 to 6 ?m, and the volume of about 5 mL or less of the dispersed phase comprises a unit dose of an active compound. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis.