Patents by Inventor Uz Martin STAMMBERGER

Uz Martin STAMMBERGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC COMBINATIONS COMPRISING A CRAF INHIBITOR
    Publication number: 20240000789
    Abstract: The present invention provides a pharmaceutical combination comprising a CRAF inhibitor in combination with (i) an ERK inhibitor or (ii) a MEK inhibitor or (iii) a CDK4/6 inhibitor, each as defined herein, or independently in each case a pharmaceutically acceptable salt thereof, for use in the treatment of NRAS-mutant melanoma and in the treatment of BRAF-mutant melanoma. wherein the melanoma may be unresectable and/or metastatic melanoma.
    Type: Application
    Filed: May 11, 2021
    Publication date: January 4, 2024
    Inventors: Giordano Caponigro, Vesselina Cooke, Uz Martin Stammberger, Darrin Stuart
  • THERAPEUTIC COMBINATIONS COMPRISING A RAF INHIBITOR FOR USE IN TREATING BRAF MUTANT NSCLC
    Publication number: 20230226030
    Abstract: The present invention provides a pharmaceutical combination comprising a CRAF inhibitor plus (i) an ERK inhibitor or (ii) a MEK inhibitor, for use in the treatment of non-small cell lung cancer (NSCLC) where the carcinoma cells of the NSCLC harbor a mutation of BRAF other than the BRAF V600E-mutant, and related invention aspects. The present invention also provides dosages and dosage regimens of a CRAF inhibitor with an ERK inhibitor or with trametinib for use in the treatment of BRAF V600 mutant (e.g. BRAF V600E mutant) NSCLC.
    Type: Application
    Filed: February 17, 2021
    Publication date: July 20, 2023
    Inventors: Giordano CAPONIGRO, Uz Martin STAMMBERGER