Patents by Inventor Vaclav MATOUSEK

Vaclav MATOUSEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10669250
    Abstract: Described herein are hypervalent iodine reagents.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: June 2, 2020
    Assignees: ETH ZURICH
    Inventors: Vaclav Matousek, Petr Beier, Antonio Togni
  • Patent number: 10590091
    Abstract: Process for the preparation of azidoperfluoroalkanes and azidopolyfluoroalkanes of general formula RF—N3, where RF is chosen from a group containing CnF2n+1, CnFxH2n+1?x, CnFxX2n+1?x or R1CF2CF2, where n is an integer in the range of 1 to 10, x is an integer in the range of 2 to 20, X is Cl, Br, or I, R1 is C1-10 alkyl, ArO, ArS, imidazolyl, benzimidazolyl, or pyrazolyl and Ar is phenyl or substituted phenyl, by the reaction of electrophilic azidation reagent of general formula R2—N3, where R2 is n-C4F9SO2, ArSO2, Br, I, with synthetic equivalent of polyfluoroalkylated carbanion of general formula [RF]?.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: March 17, 2020
    Assignees: Ustav Organicke Chemie A Biochemie AV CR , v.v.i., CF Plus Chemicals s.r.o.
    Inventors: Petr Beier, Vaclav Matousek, Zsofia E. Blastik, Svatava Voltrova
  • Publication number: 20190161452
    Abstract: Process for the preparation of azidoperfluoroalkanes and azidopolyfluoroalkanes of general formula RF—N3, where RF is chosen from a group containing CnF2n+1, CnFxH2n+1?x, CnFxX2n+1?x or R1CF2CF2, where n is an integer in the range of 1 to 10, x is an integer in the range of 2 to 20, X is Cl, Br, or I, R1 is C1-10 alkyl, ArO, ArS, imidazolyl, benzimidazolyl, or pyrazolyl and Ar is phenyl or substituted phenyl, by the reaction of electrophilic azidation reagent of general formula R2—N3, where R2 is n-C4F9SO2, ArSO2, Br, I, with synthetic equivalent of polyfluoroalkylated carbanion of general formula [RF]?.
    Type: Application
    Filed: November 30, 2017
    Publication date: May 30, 2019
    Applicants: Ustav organicke chemie a biochemie AV CR, v.v.i., CF Plus Chemicals s.r.o.
    Inventors: Petr BEIER, Vaclav MATOUSEK, Zsofia E. BLASTIK, Svatava VOLTROVA
  • Publication number: 20190040036
    Abstract: Described herein are hypervalent iodine reagents.
    Type: Application
    Filed: August 6, 2018
    Publication date: February 7, 2019
    Applicants: ETH Zurich, INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC, V.V.I
    Inventors: Vaclav MATOUSEK, Petr BEIER, Antonio TOGNI
  • Patent number: 10040812
    Abstract: A hypervalent iodine of formula (I) or formula (II) wherein R is a nucleophile and a method for their production is described. Such compounds can be used for fluoroethylation of compounds carrying a reactive group. A preferred compound carrying a reactive group is cystein in any environment such as peptide targets.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: August 7, 2018
    Assignees: ETH ZURICH, INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC, V.V.I
    Inventors: Vaclav Matousek, Petr Beier, Antonio Togni
  • Publication number: 20170233420
    Abstract: A hypervalent iodine of formula (I) or formula (II) wherein R is a nucleophile and a method for their production is described. Such compounds can be used for fluoroethylation of compounds carrying a reactive group. A preferred compound carrying a reactive group is cystein in any environment such as peptide targets.
    Type: Application
    Filed: August 3, 2015
    Publication date: August 17, 2017
    Applicants: ETH Zurich, INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC, V.V.I
    Inventors: Vaclav MATOUSEK, Petr BEIER, Antonio TOGNI