Patents by Inventor Vahid Zia

Vahid Zia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
    Patent number: 8329727
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: December 11, 2012
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
  • CRYSTALLINE PYRIDAZINE COMPOUND
    Publication number: 20120108601
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Application
    Filed: December 23, 2011
    Publication date: May 3, 2012
    Applicants: Gilead Sciences, Inc., Gerhard Puerstinger, K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Crystalline pyridazine compound
    Patent number: 8106054
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: January 31, 2012
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • S-[2-[(1-iminoethy)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride crystalline salt
    Patent number: 7767850
    Abstract: A novel mixed salt of S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine is disclosed. The novel mixed salt, S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, may be produced to form crystals that may be arranged as generally orderly packed agglomerates, which are particularly useful in making pharmaceutical compositions. Such pharmaceutical compositions are also described, as well as methods to make crystalline S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, and methods of treating conditions characterized by an overexpression on nitric oxide from the inducible isoform of nitric oxide synthase using the S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: August 3, 2010
    Assignee: Pfizer Inc.
    Inventors: Lyle Brostrom, Ann Czyzewski, Vahid Zia, Ahmad Sheikh
  • Pyridazine compound and use thereof
    Patent number: 7754720
    Abstract: A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating compound (1) are provided.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: July 13, 2010
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard Puerstinger
    Inventors: Steven S. Bondy, Terrence C. Dahl, David A. Oare, Reza Oliyai, Winston C. Tse, Vahid Zia
  • NOVEL PYRIDAZINE COMPOUND AND USE THEREOF
    Publication number: 20100152444
    Abstract: A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating compound (1) are provided.
    Type: Application
    Filed: February 18, 2010
    Publication date: June 17, 2010
    Applicants: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard Puerstinger
    Inventors: Steven S. Bondy, Terrenc C. Dahl, David A. Oare, Reza Oliyai, Winston C. Tse, Vahid Zia
  • NOVEL PYRIDAZINE COMPOUND AND USE THEREOF
    Publication number: 20100063059
    Abstract: A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections. Methods of making and formulating compound (1) are provided.
    Type: Application
    Filed: July 6, 2007
    Publication date: March 11, 2010
    Applicants: Gilead Sciences, Inc., K. U. Leuven Research & Development
    Inventors: Steven S. Bondy, Terrence C. Dahl, David A. Oare, Reza Oliyai, Winston C. Tse, Vahid Zia
  • IMIDAZO[4,5-c]PYRIDINE COMPOUNDS AND METHODS OF ANTIVIRAL TREATMENT
    Publication number: 20100028301
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.
    Type: Application
    Filed: October 13, 2009
    Publication date: February 4, 2010
    Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
  • Imidazo 4,5-c pyridine compounds and methods of antiviral treatment
    Patent number: 7648998
    Abstract: The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening ofcompounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: January 19, 2010
    Assignees: K.U. Leuven Research & Development, Gilead Sciences, Inc.
    Inventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
  • S-[2-[(1-lminoethy)Amino]Ethyl]-2-Methyl-L-Cysteine Maleate Hydrochloride Crystalline Salt
    Publication number: 20090215891
    Abstract: A novel mixed salt of S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine is disclosed. The novel mixed salt, S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, may be produced to form crystals that may be arranged as generally orderly packed agglomerates, which are particularly useful in making pharmaceutical compositions. Such pharmaceutical compositions are also described, as well as methods to make crystalline S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, and methods of treating conditions characterized by an overexpression on nitric oxide from the inducible isoform of nitric oxide synthase using the S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride.
    Type: Application
    Filed: December 5, 2008
    Publication date: August 27, 2009
    Applicant: Pfizer, Inc.
    Inventors: Lyle Brostrom, Ann Czyzewski, Vahid Zia, Ahmad Sheikh
  • Crystalline pyridazine compound
    Publication number: 20090036460
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Application
    Filed: July 3, 2008
    Publication date: February 5, 2009
    Applicants: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard Puerstinger
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Novel pyridazine compound and use thereof
    Publication number: 20080199427
    Abstract: A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating compound (1) are provided.
    Type: Application
    Filed: July 6, 2007
    Publication date: August 21, 2008
    Inventors: Steven S. Bondy, Terrence C. Dahl, David A. Oare, Reza Oliyai, Winston C. Tse, Vahid Zia
  • Processes and intermediates useful for preparing integrase inhibitor compounds
    Publication number: 20080039487
    Abstract: The invention provides processes and intermediates useful for preparing integrase inhibiting compounds.
    Type: Application
    Filed: December 21, 2006
    Publication date: February 14, 2008
    Inventors: Jared Evans, Jay Parrish, Dominika Pcion, Richard Polniaszek, Christina Schmidt, Richard Yu, Vahid Zia
  • Imidazo 4,5-C Pyridine Compounds and Methods of Antiviral Treatment
    Publication number: 20070244148
    Abstract: The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general formula (Z): The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula and their use as a medicine or to treat or prevent viral infections.
    Type: Application
    Filed: December 21, 2004
    Publication date: October 18, 2007
    Inventors: Steven Bondy, Eric Dowdy, Choung Kim, David Oare, Johan Neyts, Vahid Zia, Gerhard Purstinger
  • Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
    Publication number: 20050222198
    Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general formula (A): wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general formula and their use in the treatment or prophylaxis of viral infections.
    Type: Application
    Filed: December 21, 2004
    Publication date: October 6, 2005
    Inventors: Steven Bondy, Eric Dowdy, Choung Kim, Johan Neyts, David Oare, Gerhard Puerstinger, Vahid Zia
  • S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride crystalline salt
    Publication number: 20050038120
    Abstract: A novel mixed salt of S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine is disclosed. The novel mixed salt, S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, may be produced to form crystals that may be arranged as generally orderly packed agglomerates, which are particularly useful in making pharmaceutical compositions. Such pharmaceutical compositions are also described, as well as methods to make crystalline S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride, and methods of treating conditions characterized by an overexpression on nitric oxide from the inducible isoform of nitric oxide synthase using the S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride.
    Type: Application
    Filed: March 10, 2004
    Publication date: February 17, 2005
    Inventors: Lyle Brostrom, Ann Czyzewski, Vahid Zia, Ahmad Sheikh