Patents by Inventor Vahuni KARAPETYAN

Vahuni KARAPETYAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphs and new path to synthesize Tafamidis
    Patent number: 11208391
    Abstract: The present invention relates to a new path to synthesize crystalline Tafamidis polymorphs starting from a Tafamidis acetic acid adduct. In addition, this invention relates to a process to synthesize Tafamidis (2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid * (2R,3R,4R,5S)-6-(methyl-amino)-hexane-1,2,3,4,5-pentol), new Tafamidis crystalline polymorphs, a pharmaceutical compositions comprising the new crystalline polymorphs and to the therapeutic use of such new polymorphs.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: December 28, 2021
    Assignee: AZAD Pharma AG
    Inventors: Karine Barseghyan, Davit Hambardzumyan, Grigor Gevorgyan, Vahuni Karapetyan, Kristine Nerkararyan, Thomas Maier
  • NEW POLYMORPHS AND NEW PATH TO SYNTHESIZE TAFAMIDIS
    Publication number: 20200399234
    Abstract: The present invention relates to a new path to synthesize crystalline Tafamidis polymorphs starting from a Tafamidis acetic acid adduct. In addition, this invention relates to a process to synthesize Tafamidis (2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid*(2R,3R,4R,5S)-6-(methyl-amino)-hexane-1,2,3,4,5-pentol), new Tafamidis crystalline polymorphs, a pharmaceutical compositions comprising the new crystalline polymorphs and to the therapeutic use of such new polymorphs.
    Type: Application
    Filed: March 13, 2019
    Publication date: December 24, 2020
    Inventors: Karine BARSEGHYAN, Davit HAMBARDZUMYAN, Grigor GEVORGYAN, Vahuni KARAPETYAN, Kristine NERKARARYAN, Thomas MAIER