Patents by Inventor Vaibhav Chinubhai Doshi

Vaibhav Chinubhai Doshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARATION OF CRYSTALLINE CLOPIDOGREL HYDROGEN SULPHATE FORM I
    Publication number: 20100081839
    Abstract: The present invention describes an improved industrial process for crystallizing out polymorph ‘Form I’ of (+) clopidogrel hydrogen sulphate (also called clopidogrel bisulphate) in) from either a Type-1 solvent or liquid characterized by comprising two or more functional groups or their mixtures thereof; or a Type-II solvent and/or solvent mixture selected from the group of methyl ethyl ketone, cyclopentylmethyl ether, dipropylglycolether, dibutylglycol ether, propylmethyl cellosolve, butylmethylcellosolve, propylethylellosolve, butylethylcellosolve or their cross combinations in a reproducible manner without detectable contamination of polymorph designated as ‘Form II’. The invention also discloses improvements in the preparation of clopidogrel free base and process for recovery and recycling of resolving agent camphor sulphonic acid.
    Type: Application
    Filed: July 24, 2009
    Publication date: April 1, 2010
    Applicant: IPCA Laboratories Ltd.
    Inventors: Ashok KUMAR, Priti Jayesh Bhayani, Vaibhav Chinubhai Doshi, Ashvini Saxena, Gunjan Pramod Pathak, Rashmi Abhyankar, Sarvanan Manavalan, Mukesh Purohit, Santosh Parihar
  • Novel crystalline forms of (S)-N-(1-Carboxy-2-methyl-prop-1-y)-N-pentanoyl-N[2'-(1H-tetrazol-5-yl)bi-phenyl-4-ylmethyl]-amine
    Publication number: 20080261959
    Abstract: This invention relates to novel crystalline forms of valsartan, namely Form A, Form B, Form C, Form D and their solvates thereof. Processes for the preparation of the novel forms are also provided. The present invention further relates to novel processes for preparing a stable amorphous form of valsartan, and in this connection, to the amorphous form of valsartan produced by such processes. The present invention also discloses a novel process for obtaining stable Form I crystals of valsartan.
    Type: Application
    Filed: November 21, 2007
    Publication date: October 23, 2008
    Inventors: Ashok Kumar, Manmohan Madhavrao Nimbalkar, Priti Jayesh Bhayani, Mukesh Subhodh Jha, Vaibhav Chinubhai Doshi
  • Process for the preparation of crystalline clopidogrel hydrogen sulphate Form I
    Publication number: 20080188663
    Abstract: The present invention describes an improved industrial process for crystallizing polymorph Form I of (+) clopidogrel hydrogen sulphate (also called clopidogrel bisulphate) in either a Type-I solvent or a Type-II. Type I solvent is an organic solvent containing two or more functional groups with a proviso that at least one functional group is different from the other(s). The Type II solvent is selected from methyl ethyl ketone, cyclopentylmethyl ether, dipropylglycolether, dibutylglycol ether, propylmethyl cellosolve, butylmethylcellosolve, propylethylellosolve, butylethylcellosolve or their cross combinations. The process produces Form I in a reproducible manner without detectable contamination of polymorph designated as Form II.
    Type: Application
    Filed: January 28, 2008
    Publication date: August 7, 2008
    Inventors: Ashok Kumar, Priti J. Bhayani, Vaibhav Chinubhai Doshi, Ashvini Saxena, Gunjan Pramod Pathak, Rashmi Abhyankar, Sarvanan Manavalan, Mukesh Purohit