Patents by Inventor Vaibhav Narayan
Vaibhav Narayan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240021192Abstract: System and method for detecting cognitive decline in a subject using a classification system for detecting cognitive decline in the subject based on a speech sample. The classification system is trained using speech data corresponding to audio recordings of speech from normal and cognitive decline patients to generate an ensemble classifier comprising a plurality of component classifiers and an ensemble module. Each of the plurality of component classifiers is a machine-learning classifier configured to generate a component output identifying a sample data as corresponding to a normal patient or a cognitive patient. The machine-learning classifier is generated based on a subset of available features. The ensemble module receives component outputs from all of the component classifiers and generates an ensemble output identifying the sample data as corresponding to a normal or cognitive decline patient based on the component outputs.Type: ApplicationFiled: April 17, 2023Publication date: January 18, 2024Applicant: Janssen Pharmaceutica NVInventors: Srinivasan VAIRAVAN, Vaibhav NARAYAN
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Publication number: 20230301573Abstract: The invention provides methods of identifying schizophrenia patients at risk for relapse. The invention also provides methods of early detection of schizophrenic relapse. The disclosed methods use monitoring of a subset of symptoms and/or one or more biomarkers. The symptom severity can be assessed using the Positive and Negative Syndrome Scale (PANSS) parameters. The methods of the invention can be used to provide early intervention to decrease or prevent relapse in schizophrenia patients.Type: ApplicationFiled: May 9, 2023Publication date: September 28, 2023Applicant: JANSSEN PHARMACEUTICA NVInventors: Dai Wang, Srihari Gopal, Vaibhav Narayan, Adam Savitz, Susan Baker
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Patent number: 11723569Abstract: The invention provides methods of identifying schizophrenia patients at risk for relapse. The invention also provides methods of early detection of schizophrenic relapse. The disclosed methods use monitoring of a subset of symptoms and/or one or more biomarkers. The symptom severity can be assessed using the Positive and Negative Syndrome Scale (PANSS) parameters. The methods of the invention can be used to provide early intervention to decrease or prevent relapse in schizophrenia patients.Type: GrantFiled: November 21, 2017Date of Patent: August 15, 2023Assignee: JANSSEN PHARMACEUTICA NVInventors: Dai Wang, Srihari Gopal, Vaibhav Narayan, Adam Savitz, Susan Baker
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Publication number: 20230245773Abstract: A system and computer-implemented method for detecting return of depression of a patient is provided. The system comprises a wearable device configured to detect movement of the patient and configured to generate actigraphy data corresponding to the movement of the patient and a computing device for retrieving actigraphy data from the device. The system and method obtain training data, including training actigraphy data, over a training period and train an anomaly detector using the training data. The system and method subsequently obtain test data from the patient, extract a plurality of features from the test data, and analyze the extracted data using the trained anomaly detector. A self-report test is used to determine whether an anomaly identified by the anomaly detector indicates that the patient is likely to experience return of depression.Type: ApplicationFiled: July 6, 2021Publication date: August 3, 2023Applicant: JANSSEN PHARMACEUTICA NVInventors: SRINIVASAN VAIRAVAN, VAIBHAV NARAYAN, RANDALL MORRISON
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Patent number: 11631395Abstract: System and method for detecting cognitive decline in a subject using a classification system for detecting cognitive decline in the subject based on a speech sample. The classification system is trained using speech data corresponding to audio recordings of speech from normal and cognitive decline patients to generate an ensemble classifier comprising a plurality of component classifiers and an ensemble module. Each of the plurality of component classifiers is a machine-learning classifier configured to generate a component output identifying a sample data as corresponding to a normal patient or a cognitive patient. The machine-learning classifier is generated based on a subset of available features. The ensemble module receives component outputs from all of the component classifiers and generates an ensemble output identifying the sample data as corresponding to a normal or cognitive decline patient based on the component outputs.Type: GrantFiled: April 14, 2020Date of Patent: April 18, 2023Assignee: Janssen Pharmaceutica NVInventors: Srinivasan Vairavan, Vaibhav Narayan
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Publication number: 20200327882Abstract: System and method for detecting cognitive decline in a subject using a classification system for detecting cognitive decline in the subject based on a speech sample. The classification system is trained using speech data corresponding to audio recordings of speech from normal and cognitive decline patients to generate an ensemble classifier comprising a plurality of component classifiers and an ensemble module. Each of the plurality of component classifiers is a machine-learning classifier configured to generate a component output identifying a sample data as corresponding to a normal patient or a cognitive patient. The machine-learning classifier is generated based on a subset of available features. The ensemble module receives component outputs from all of the component classifiers and generates an ensemble output identifying the sample data as corresponding to a normal or cognitive decline patient based on the component outputs.Type: ApplicationFiled: April 14, 2020Publication date: October 15, 2020Inventors: Srinivasan VAIRAVAN, Vaibhav NARAYAN
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Publication number: 20200116726Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.Type: ApplicationFiled: July 24, 2019Publication date: April 16, 2020Inventors: Bruno Domon, Ian McCaffrey, Vaibhav Narayan, Scott Patterson
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Publication number: 20180140242Abstract: The invention provides methods of identifying schizophrenia patients at risk for relapse. The invention also provides methods of early detection of schizophrenic relapse. The disclosed methods use monitoring of a subset of symptoms and/or one or more biomarkers. The symptom severity can be assessed using the Positive and Negative Syndrome Scale (PANSS) parameters. The methods of the invention can be used to provide early intervention to decrease or prevent relapse in schizophrenia patients.Type: ApplicationFiled: November 21, 2017Publication date: May 24, 2018Inventors: Dai Wang, Srihari Gopal, Vaibhav Narayan, Adam Savitz, Susan Baker
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Publication number: 20170219591Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.Type: ApplicationFiled: December 13, 2016Publication date: August 3, 2017Inventors: Bruno DOMON, Ian MCCAFFREY, Vaibhav NARAYAN, Scott PATTERSON
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Publication number: 20160166510Abstract: The present invention provides stabilized prolonged release pharmaceutical compositions comprising atypical antipsychotic drug like paliperidone or pharmaceutically acceptable salts thereof without incorporating surfactant and for water penetration enhancer. Such compositions are preferably in the form of a matrix wherein one or more release controlling agents are present in and/or on the matrix. Further, such compositions comprise one or more release controlling agent and exhibits desired in vitro release of drug with or without lag period. The invention also provides a process for the preparation of such compositions.Type: ApplicationFiled: January 14, 2016Publication date: June 16, 2016Applicant: INVENTIA HEALTHCARE PRIVATE LIMITEDInventors: Sunil Deviprasad Tiwari, Vijayendrakumar Virendrakumarji Redasani, Prasad Shrikantrao Joshi, Vaibhav Narayan Sawarkar, Ankur Janak Shah
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Patent number: 9271939Abstract: The present invention provides stabilized prolonged release pharmaceutical compositions comprising atypical antipsychotic drug like paliperidone or pharmaceutically acceptable salts thereof without incorporating surfactant and/or water penetration enhancer. Such compositions are preferably in the form of a matrix wherein one or more release controlling agents are present in and/or on the matrix. Further, such compositions comprise one or more release controlling agent and exhibits desired in vitro release of drug with or without lag period. The invention also provides a process for the preparation of such compositions.Type: GrantFiled: March 11, 2011Date of Patent: March 1, 2016Assignee: Inventia Healthcare Private LimitedInventors: Sunil Deviprasad Tiwari, Vijayendrakumar Virendrakumarji Redasani, Prasad Shrikantrao Joshi, Vaibhav Narayan Sawarkar, Ankur Janak Shah
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Publication number: 20150132286Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.Type: ApplicationFiled: September 18, 2014Publication date: May 14, 2015Inventors: Bruno DOMON, Ian MCCAFFREY, Vaibhav NARAYAN, Scott PATTERSON
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Patent number: 8865413Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.Type: GrantFiled: May 4, 2011Date of Patent: October 21, 2014Assignee: Celera CorporationInventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
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Publication number: 20130162536Abstract: The present invention in a preferred embodiment provides systems and methods for enabling or accessing or viewing components through a graphical user interface, wherein the system comprises, a) an input assembly; b) a screen unit; and c) an electronic device; wherein the said input assembly comprises, i. a sensory component; ii. a data processing unit; and iii.Type: ApplicationFiled: December 5, 2012Publication date: June 27, 2013Inventor: Vaibhav Narayan Khedkar
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Publication number: 20130012524Abstract: The present invention provides stabilized prolonged release pharmaceutical compositions comprising atypical antipsychotic drug like paliperidone or pharmaceutically acceptable salts thereof without incorporating surfactant and/or water penetration enhancer. Such compositions are preferably in the form of a matrix wherein one or more release controlling agents are present in and/or on the matrix. Further, such compositions comprise one or more release controlling agent and exhibits desired in vitro release of drug with or without lag period. The invention also provides a process for the preparation of such compositions.Type: ApplicationFiled: March 11, 2011Publication date: January 10, 2013Applicant: Inventia Healthcare Private LimitedInventors: Sunil Deviprasad Tiwari, Vijayendrakumar Videndrakumarji Redasani, Prasad Shrikantrao Joshi, Vaibhav Narayan Sawarkar, Ankur Janak Shah
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Publication number: 20120128677Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.Type: ApplicationFiled: May 4, 2011Publication date: May 24, 2012Applicant: CELERA CORPORATIONInventors: Bruno DOMON, Ian MCCAFFERY, Vaibhav NARAYAN, Scott PATTERSON
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Publication number: 20090138977Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.Type: ApplicationFiled: October 3, 2008Publication date: May 28, 2009Applicant: CELERA CORPORATIONInventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
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Publication number: 20090123461Abstract: The present invention provides a method for diagnosing and detecting cancer. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in cancer (podocalyxin) and antibodies that bind podocalyxins. The present invention provides that podocalyxins are used as targets for screening agents that modulate podocalyxin activities. Further the present invention provides methods for treating diseases associated with podocalyxin expression.Type: ApplicationFiled: October 21, 2008Publication date: May 14, 2009Applicant: Celera CorporationInventors: William Fitzhugh, Steve Ruben, Vaibhav Narayan, Charles E. Birse
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Patent number: 7473531Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.Type: GrantFiled: August 6, 2004Date of Patent: January 6, 2009Assignee: Colora CorporationInventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
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Publication number: 20070059757Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of E-cadherin in comparison to healthy cells. Also provided are antagonists or agonists of E-cadherin, and methods for screening agents that modulate the E-cadherin level or activity in vivo or in vitro.Type: ApplicationFiled: November 13, 2006Publication date: March 15, 2007Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson