Patents by Inventor Vaibhav Tiwari

Vaibhav Tiwari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-heparan sulfate peptides that block herpes simplex virus infection in vivo
    Patent number: 9464113
    Abstract: Provided are anti-heparan sulfate peptides and methods that employ those peptides for the prevention or treatment of viral infections, including herpesviral infections such as ?-herpesviral, ?-herpesviral, and ?-herpesviral infections, which are exemplified by HSV-1. CMV, and HHV-8 viral infections, respectively. Peptides may comprise at least 10 amino acids of the amino acid sequences (SEQ?ID?NO:?2) XRXRXKXXRXRX, (SEQ?ID?NO:?8) XRXRXXKXRXRX, (SEQ?ID?NO:?4) XXRRRRXRRRXK, and/or (SEQ?ID?NO:?10) KXRRRXRRRRXX, wherein X represents any amino acid. In some embodiments, peptides comprise at least 10 amino acids of the sequence LRSRTKIIRIRH (SEQ ID NO: 1), HRIRIIKTRSRL (SEQ ID NO: 7), MPRRRRIRRRQK (SEQ ID NO: 3), and/or KQRRRIRRRRM (SEQ ID NO: 9).
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: October 11, 2016
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Deepak Shukla, Vaibhav Tiwari
  • Virus traps
    Patent number: 9182399
    Abstract: Specific applications of particles and particle agglomerates with semiconductor surfaces are provided. The particles and particle agglomerates display a high affinity for viral particles, and may be used therapeutically and/or prophylactically to treat or prevent viral infections. The particles and particle agglomerates may also be used to remove viral particles from a surface or fluid, e.g., as an absorbent in a filter, applied to surfaces to render them virostatic, and as tool to handle viral particles, e.g., for research, diagnostic, or decontamination purposes.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: November 10, 2015
    Assignees: Christian-Albrechts-Universitaet Zu Kiel, Universitatsklinikum Schleswig-Holsten, Western University of Health Sciences, The Board of Trustees of the University of Illinois
    Inventors: Rainer Adelung, Yogendra Kumar Mishra, Claudia Röhl, Deepak Shukla, Frank Spors, Vaibhav Tiwari
  • ANTI-HEPARAN SULFATE PEPTIDES THAT BLOCK HERPES SIMPLEX VIRUS INFECTION IN VIVO
    Publication number: 20150093825
    Abstract: Provided are anti-heparan sulfate peptides and methods that employ those peptides for the prevention or treatment of viral infections, including herpesviral infections such as ?-herpesviral, ?-herpesviral, and ?-herpesviral infections, which are exemplified by HSV-1. CMV, and HHV-8 viral infections, respectively. Peptides may comprise at least 10 amino acids of the amino acid sequences (SEQ?ID?NO:?2) XRXRXKXXRXRX, (SEQ?ID?NO:?8) XRXRXXKXRXRX, (SEQ?ID?NO:?4) XXRRRRXRRRXK, and/or (SEQ?ID?NO:?10) KXRRRXRRRRXX, wherein X represents any amino acid. In some embodiments, peptides comprise at least 10 amino acids of the sequence LRSRTKIIRIRH (SEQ ID NO: 1), HRIRIIKTRSRL (SEQ ID NO: 7), MPRRRRIRRRQK (SEQ ID NO: 3), and/or KQRRRIRRRRM (SEQ ID NO: 9).
    Type: Application
    Filed: November 26, 2014
    Publication date: April 2, 2015
    Inventors: Deepak Shukla, Vaibhav Tiwari
  • VIRUS TRAPS
    Publication number: 20140056947
    Abstract: Specific applications of particles and particle agglomerates with semiconductor surfaces are provided. The particles and particle agglomerates display a high affinity for viral particles, and may be used therapeutically and/or prophylactically to treat or prevent viral infections. The particles and particle agglomerates may also be used to remove viral particles from a surface or fluid, e.g., as an absorbent in a filter, applied to surfaces to render them virostatic, and as tool to handle viral particles, e.g., for research, diagnostic, or decontamination purposes.
    Type: Application
    Filed: August 24, 2012
    Publication date: February 27, 2014
    Applicants: CHRISTIAN-ALBRECHTS-UNIVERSITAT ZU KIEL, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, WESTERN UNIVERSITY OF HEALTH SCIENCES, UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN
    Inventors: Rainer Adelung, Yogendra Kumar Mishra, Claudia Röhl, Deepak Shukla, Frank Spors, Vaibhav Tiwari
  • Purified and isolated heparan sulfate 3--sulfotransferase isoform 5 nucleic acids and polypeptides and therapeutic and screening methods using same
    Patent number: 7531338
    Abstract: 3-OST-5 proteins, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to 3-OST-5 homologs, and methods of producing the same, are also disclosed. 3OST-5 gene products have biological activity in specific heparan sulfate 3-O-sulfotransferase reactions. These reactions provide unique modified heparan sulfate. Thus, therapeutic methods involving this activity are also disclosed.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: May 12, 2009
    Assignees: The University of North Carolina at Chapel Hill, The Board of Trustees of the University of Illinois
    Inventors: Jian Liu, Guoqing Xia, Jinghua Chen, Michael B. Duncan, Deepak Shukla, Vaibhav Tiwari, Anders Malmstrom
  • Purified and isolated heparan sulfate 3-o-sulfotransferase isoform 5 nucleic acids and polypeptides and therapeutic and screening methods using same
    Publication number: 20060165673
    Abstract: 3-OST-5 proteins, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to 3-OST-5 homologs, and methods of producing the same, are also disclosed. 3OST-5 gene products have biological activity in specific heparan sulfate 3-O-sulfotransferase reactions. These reactions provide unique modified heparan sulfate. Thus, therapeutic methods involving this activity are also disclosed.
    Type: Application
    Filed: July 7, 2003
    Publication date: July 27, 2006
    Inventors: Jian Liu, Guoqing Xia, Jinghua Chen, Michael Duncan, Deepark Shuka, Vaibhav Tiwari, Anders Malmstrom