Patents by Inventor Vaidya Jayathirtha Rao

Vaidya Jayathirtha Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of indolizine based derivatives as potential phosphodiestrase 3 (PDE3) inhibitors
    Patent number: 9562045
    Abstract: The present invention provides compounds of general formula 1 useful as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: February 7, 2017
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Budde Mahendar, Saidulu Mattapally, Mettu Ravinder, Sanjay Kumar Banerjee, Vaidya Jayathirtha Rao
  • Pyridopyrimidine based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof
    Patent number: 9505760
    Abstract: The present invention provides compounds of formula 1 as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: November 29, 2016
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Budde Mahendar, Saidulu Mattapally, Mettu Ravinder, Sanjay Kumar Banerjee, Vaidya Jayathirtha Rao
  • PYRIDOPYRIMIDINE BASED DERIVATIVES AS POTENTIAL PHOSPHODIESTERASE 3 (PDE3) INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20160194319
    Abstract: The invention relates to a process for the synthesis of pyridopyrimidine derivatives, which work as PDE3 inhibitors.
    Type: Application
    Filed: January 6, 2016
    Publication date: July 7, 2016
    Inventors: Budde MAHENDAR, Saidulu MATTAPALLY, Mettu RAVINDER, Sanjay Kumar BANERJEE, Vaidya Jayathirtha RAO
  • PROCESS FOR PREPARATION OF INDOLIZINE BASED DERIVATIVES AS POTENTIAL PHOSPHODIESTRASE 3 (PDE3) INHIBITORS
    Publication number: 20160159792
    Abstract: The present invention provides compounds of general formula 1 useful as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
    Type: Application
    Filed: January 19, 2016
    Publication date: June 9, 2016
    Inventors: Budde MAHENDAR, Saidulu MATTAPALLY, Mettu RAVINDER, Sanjay Kumar BANERJEE, Vaidya Jayathirtha RAO
  • Indolizinone based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof
    Patent number: 9249139
    Abstract: The present invention provides compounds of general formula A useful as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula A can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: February 2, 2016
    Assignee: Council of Scientific & Industrial Research
    Inventors: Budde Mahendar, Saidulu Mattapally, Mettu Ravinder, Sanjay Kumar Banerjee, Vaidya Jayathirtha Rao
  • Pyridopyrimidine based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof
    Patent number: 9242982
    Abstract: The present invention provides compounds of formula 1 as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: January 26, 2016
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Budde Mahendar, Saidulu Mattapally, Mettu Ravinder, Sanjay Kumar Banerjee, Vaidya Jayathirtha Rao
  • INDOLIZINONE BASED DERIVATIVES AS POTENTIAL PHOSPHODIESTERASE 3 (PDE3) INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20140296530
    Abstract: The present invention provides compounds of general formula A useful as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula A can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
    Type: Application
    Filed: January 30, 2014
    Publication date: October 2, 2014
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Budde MAHENDAR, Saidulu MATTAPALLY, Mettu RAVINDER, Sanjay Kumar BANERJEE, Vaidya Jayathirtha RAO
  • PYRIDOPYRIMIDINE BASED DERIVATIVES AS POTENTIAL PHOSPHODIESTERASE 3 (PDE3) INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20140221651
    Abstract: The present invention provides compounds of formula 1 as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula 1 can be employed as therapeutics in human and veterinary medicine, where they can be used, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
    Type: Application
    Filed: January 30, 2014
    Publication date: August 7, 2014
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Budde MAHENDAR, Saidulu MATTAPALLY, Mettu RAVINDER, Sanjay Kumar BANERJEE, Vaidya Jayathirtha RAO
  • Diazonaphthoquinonesulfonic acid bisphenol derivative useful in photo lithographic sub micron patterning and a process for preparation thereof
    Patent number: 8563215
    Abstract: The present invention provides novel diazonaphthoquinonesulfonic acid bisphenol derivatives. More particularly, the present invention relates to photo restive coating comprising alkali-soluble resin, a photoactive compound and a surfactant. The photoresist film prepared has less then one micron. The photoactive compound is soluble or swellable in aqueous alkaline solutions and is diazonaphthoquinonesulfonic bisphenol esters of the general formula (A), wherein DNQ represents a 2-Diazo-1-naphthoquinone-4-sulfonyl, 2-Diazo-1-naphthoquinone-5-sulfonyl, 1-Diazo-2-naphthoquinone-4-sulfonyl groups and R1 R1 represents an alkyl, aryl and substituted aryl groups. The invention also provides a process for coating and imaging the light-sensitive composition.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: October 22, 2013
    Assignee: Council of Scientific & Industrial Research
    Inventors: Vummadi Venkat Reddy, Vaidya Jayathirtha Rao, Mannepalli Lakshmi Kantam, Sunkara Sakunthala Madhavendra, Virendra Kumar Dwivedi
  • NOVEL DIAZONAPHTHOQUINONESULFONIC ACID BISPHENOL DERIVATIVE USEFUL IN PHOTO LITHOGRAPHIC SUB MICRON PATTERNING AND A PROCESS FOR PREPARATION THEREOF
    Publication number: 20100081084
    Abstract: The present invention provides novel diazonaphthoquinonesulfonic acid bisphenol derivatives. More particularly, the present invention relates to photo restive coating comprising alkali-soluble resin, a photoactive compound and a surfactant. The photoresist film prepared has less then one micron. The photoactive compound is soluble or swellable in aqueous alkaline solutions and is diazonaphthoquinonesulfonic bisphenol esters of the general formula (A), wherein DNQ represents a 2-Diazo-1-naphthoquinone-4-sulfonyl, 2-Diazo-1-naphthoquinone-5-sulfonyl, 1-Diazo-2-naphthoquinone-4-sulfonyl groups and R1 R1 represents an alkyl, aryl and substituted aryl groups. The invention also provides a process for coating and imaging the light-sensitive composition.
    Type: Application
    Filed: March 20, 2008
    Publication date: April 1, 2010
    Inventors: Vummadi Venkat Reddy, Vaidya Jayathirtha Rao, Mannepalli Lakshmi Kantam, Sunkara Sakumthala Madhavendra, Virendra Kumar Dwivedi
  • Antimalarial Baylis-Hillman adducts and a process for the preparation thereof
    Patent number: 7666883
    Abstract: The present invention is directed towards the synthesis of novel and new chloropyridine skeleton based compounds and these are Bayllis Hillman adducts having a remarkable in vitro anti-malarial activity. These compounds have been found to possess anti-malarial activity against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. The anti-malarial compounds of the present invention inhibit the mature schizonts in vitro.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: February 23, 2010
    Assignee: Council of Scientific and Industrial Research
    Inventors: Puli Narender, Banda Gangadasu, Uppalanchi Srinivas, Mettu Ravinder, Sriramoju Bharat Kumar, Chilukuri Ramesh, Vaidya Jayathirtha Rao, Janaswamy Madhusudhan Rao
  • Single pot process for the preparation of diazonaphthoquinonesulfonyl ester
    Patent number: 7355021
    Abstract: The present invention provides a single pot process for the preparation of diazonaphthoquinonesulfonyl ester, a useful organic material for micro electronic and dye industry. This study pertains to the one pot preparation of diazonaphthoquinonesulfonyl esters using the corresponding diazonaphthoquinine sulfonic acid or its sodium salt, diphosgene or triphosgene, variety of hydroxy compounds and tertiary organic base in an organic solvent medium.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: April 8, 2008
    Assignee: Council of Scientific & Industrial Research
    Inventors: Vummadi Venkat Reddy, Boddu Ananda Rao, Maruthi Janaki Ram Reddy, Chiguru Srinivas, Chilukuri Ramesh, Vaidya Jayathirtha Rao
  • Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde
    Patent number: 6737529
    Abstract: The present invention relates to an improved process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde which is a useful intermediate in the preparation of a variety of pharmaceutical and pesticide products.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: May 18, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Bhimapaka Chinaraju, Vaidya Jayathirtha Rao, Kondapuram Vijaya Raghavan
  • Process for preparing substituted coumarins
    Patent number: 6716996
    Abstract: The present invention relates to a process for preparing substituted coumarins. More particularly, the present invention relates to a process for preparing substituted coumarins using polyaniline salts as catalysts.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: April 6, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Palaniappan Srinivasan, Vaidya Jayathirtha Rao, Saravanan Chandrasekaran, Chandrashekar Rampally
  • Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde
    Publication number: 20030176705
    Abstract: The present invention relates to an improved process for the preparation of 2-chloro-5-methyl pyridine-3-carbaldehyde which is a useful intermediate in the preparation of a variety of pharmaceutical and pesticide products.
    Type: Application
    Filed: March 7, 2002
    Publication date: September 18, 2003
    Inventors: Bhimapaka Chinaraju, Vaidya Jayathirtha Rao, Kondapuram Vijaya Raghavan
  • 1-(2-chloro-5-methyl-3-pyridylmethyl)-2-nitroiminoimidazolidine and process for the preparation thereof
    Patent number: 6566528
    Abstract: The present invention relates to 1-(2-chloro-5-methyl-3-pyridylmethyl)-2-nitroiminoimidazolidine of the formula 1, a novel compound of class nitroimino pyridyl derivatives and to a process for the preparation thereof
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: May 20, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Chinaraju Bhimapaka, Vaidya Jayathirtha Rao
  • Process for the preparation of diazonaphthoquinonesulfonylchlorides using diphosgene and triphosgene
    Patent number: 6559291
    Abstract: The invention relates to a process for the preparation of diazonaphthoquinonesulfonylchlorides of the formula 1, 2 and 3 using diphosgene or triphosgene.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: May 6, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Vummadi Venkat Reddy, Maruthi Janaki Ram Reddy, Vaidya Jayathirtha Rao
  • 1-(2-CHLORO-5-METHYL-3-PYRIDYLMETHYL)-2-NITROIMINIOMIDAZOLIDINE AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20030083350
    Abstract: The present invention relates to 1-(2-chloro-5-methyl-3-pyridylmethyl)-2-nitroiminoimadozolidine of the formula 1, a novel compound of class nitroimino pyridyl derivatives and to a process for the preparation thereof 1
    Type: Application
    Filed: October 30, 2001
    Publication date: May 1, 2003
    Inventors: Chinaraju Bhimapaka, Vaidya Jayathirtha Rao
  • Process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde
    Patent number: 6479664
    Abstract: The present invention describes an improved process for the preparation of 2-chloro-5-methylpyridine-3-carbaldehyde from N-benzyl-N-(1-Propenyl)acetamide using diphosgene and dimethylformamide or triphosgene and dimethylformamide (Vilsmeyer reagent) in 92% yield against reported 12% yield. The present invention has the advantage of using diphosgene and triphosgene instead of toxic phosgene gas and phosphorousoxytrichloride, thereby avoiding the formation of phosphorous salt.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: November 12, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Gangadasu Banda, Chinaraju Bhimapaka, Vaidya Jayathirtha Rao