Patents by Inventor Val Goodfellow

Val Goodfellow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tri-peptide Inhibitors of Serine Elastases
    Publication number: 20090156509
    Abstract: The present invention provides compounds of formula (I): where X is R1—(CR3R4)nOC(O)—; R1—(CR3R4)nC(O)—; R1—C(O)NH(CR3R4)nOC(O)—; R1—C(O)NH(CR3R4)nC(O)—; R1—C(O)(CR3R4)nOC(O)—; or R1—C(O)(CR3R4)nC(O)—; where R1 is optionally substituted C5-10 aryl or heteroaryl; OH or NH2; where R3 and R4 are independently H or methyl; and n is 0 to 6; and Y is —CF3 or one of: where R2 is C1-8 alkyl optionally substituted with halo or —OH; —(CR6R7)p—C5-6 aryl optionally substituted with halo, —OH, C1-8 alkyl, C1-8 haloalkyl, —(CH2)mC(O)NH2 or —(CH2)mOCH3; where R6 and R7 are independently H or methyl; m is 0 to 4, and p is 0 or 1 or a pharmaceutically acceptable salt, ester, metabolite or prodrug thereof
    Type: Application
    Filed: December 2, 2008
    Publication date: June 18, 2009
    Applicant: Accuthera, Inc.
    Inventors: John C. Cheronis, Val Goodfellow, Colin J. Loweth, Shamsi Raeissi
  • Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
    Publication number: 20060178403
    Abstract: Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity. The compounds of this invention have the following structure: including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein m, n, X, R1, R2, R3, R4, and R5 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: March 8, 2004
    Publication date: August 10, 2006
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Val Goodfellow, Martin Rowbottom, Brian Dyck, Junko Tamiya, Mingzhu Zhang, Jonathan Grey, Troy Vickers
  • Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
    Patent number: 7067509
    Abstract: Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity. The compounds of this invention have the following structure: including stereoisomers and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, R5, and R6 are as defined herein. Pharmaceutical compositions containing a compound of this invention, as well as methods relating to the use thereof, are also disclosed.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: June 27, 2006
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Val Goodfellow, Martin Rowbottom, Brian P Dyck, Junko Tamiya, Mingzhu Zhang, Jonathan Grey, Troy D Vickers, Mehrak Kiankarimi, Warren Wade, Sarah Clough, Joseph Pontillo, Dongpei Wu
  • Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
    Publication number: 20050256124
    Abstract: Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity. The compounds of this invention have the following structure: including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein R1, R2, R5, Het, X and Cyc are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: April 15, 2005
    Publication date: November 17, 2005
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Val Goodfellow, Brian Dyck, Liren Zhao, Junko Tamiya, Jonathan Grey, Warren Wade, Martin Rowbottom, Mingzhu Zhang, Troy Vickers
  • Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
    Publication number: 20050176738
    Abstract: Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity. The compounds of this invention have the following structure: including pharmaceutically acceptable salts, esters, solvates, stereoisomers, and prodrugs thereof, wherein m, n, Q1, Q2, R1, R2, R3, R4, R7 and X are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
    Type: Application
    Filed: November 5, 2004
    Publication date: August 11, 2005
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Val Goodfellow, Mingzhu Zhang, Junko Tamiya
  • Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
    Publication number: 20040259931
    Abstract: Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity.
    Type: Application
    Filed: March 8, 2004
    Publication date: December 23, 2004
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Val Goodfellow, Martin Rowbottom, Brian P. Dyck, Junko Tamiya, Mingzhu Zhang, Jonathan Grey, Troy D. Vickers, Mehrak Kiankarimi, Warren Wade, Sarah Clough Hudson
  • Ligands of melanocortin receptors and compositions and methods related thereto
    Publication number: 20030158209
    Abstract: Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders.
    Type: Application
    Filed: October 9, 2002
    Publication date: August 21, 2003
    Applicant: Neurocrine Biosciences Inc.
    Inventors: Brian P. Dyck, Val Goodfellow, Teresa Phillips, Jessica Parker, Xiaohu Zhang, Chen Chen, Joe Anh Tran, Joseph Pontillo, Fabio C. Tucci