Abstract: Methods of stabilizing color in a composition, which methods comprise: (a) providing an amino-substituted hydroxybenzophenone compound corresponding to the general formula (I): and (b) combining the amino-substituted hydroxybenzophenone compound with a composition to be stabilized selected from the group consisting of cosmetic preparations and dermatological preparations, are described along with compositions containing an organic dye and an amino-substituted hydroxybenzophenone compound corresponding to the general formula (I).

Abstract: The present invention relates to surface-modified nanoparticulate metal oxides where the metal is chosen from the group consisting of aluminum, cerium, iron, titanium, zinc and zirconium, wherein the surface modification comprises a coating with a copolymer P of A) 60 to 99 mol % of an N-vinyllactam and B) 1 to 40 mol % of a monomer chosen from the group of b1) C8-C30-alkyl esters of monoethylenically unsaturated C3-C8-carboxylic acids b2) N-alkyl- or N,N-dialkyl-substituted amides of acrylic acid or of methacrylic acid with C8-C8-alkyl radicals, or b3) vinyl esters of aliphatic C8-C30-carboxylic acids, or mixtures of these monomers.

Abstract: The present invention relates to surface-modified nanoparticulate metal oxides, methods for their production and use thereof as UV filters in cosmetic preparations.

Abstract: The present invention relates to the modification of surface properties of particulate, linear, sheet-like, or three-dimensional structures using alkoxylated polyvinylamines. The invention further relates to novel alkoxylated polyvinylamines, and also to a process for their preparation.

Abstract: The present invention relates to the formation of surface treated zinc oxide and titania particles, and in particular zinc oxide and titania nanoparticles, with a siloxane star-graft copolymer coating, comprising a looped and/or linear polymeric structure on a star-graft copolymer coating, on a particle surface to control the interfacial surface interactions between the particle and the oil phase of the cosmetic skin formulation.

Abstract: The invention relates to a method of producing powdered preparations comprising diethylamino hydroxybenzoly hexyl benzoate of formula I the method comprising: a) dispersing the benzoyl benzoate of formula I in an aqueous molecularly disperse or colloidally disperse solution of a protective colloid and b) converting the dispersion obtained into a dry powder by removing the water and and drying, wherein the protective colloid used in process step a) is modified starch.

Abstract: The invention relates to a method of producing powdered preparations comprising 2,4,6 trianilino p (carbo 2?-ethylexyl-1?-oxy)-1,3,5 triazine of the formula I and diethylamino hydroxybenzoyl hexyl benzoate of the formula II the method comprising: a) jointly dispersing the compounds I and II in an aqueous molecularly disperse or colloidally disperse solution of a protective colloid; and b) converting the dispersion obtained into a dry powder by removing the water and drying, wherein the protective colloid used in process step a) is modified starch.

Abstract: The invention relates to a method of producing powdered preparations comprising 2,4,6-trianilino-p-carbo-2?-ethylhexyl-1?-oxy)-1,3,5-triazine of formula I by the method comprising: a) dispersing the triazine of formula I in an aqueous molecularly disperse or colloidally disperse solution of a protective colloid and b) converting the dispersion obtained into a dry powder by removing the water and and drying, wherein the protective colloid used in process step a) is modified starch.

Abstract: The invention relates to a mixture consisting of a UV-A filter of the formula I and a UV-B filter of the formula II.

Abstract: a cell culture device is disclosed having at least one cell-supporting layer of porous material obtained by dehydration of an aqueous gel which is poured directly either into said well bottom or into the bottom of a cradle or insert of a size which is adapted for being insertable into the volume of the well, thereby enabling by a robot or an automaton itself commanded by you computer.

Abstract: The present invention relates to a particulate, linear, sheet-like or three-dimensional structure comprising, at least on its surface, a hydrophilicizing amount of at least one acylated polyamine, where at least some of the polyamine nitrogen atoms bear acyl radicals of the formula I R1—CO—??(I) where R1 is hydrogen, C1–C27-alkyl, C7–C27-alkenyl or C6–C10-aryl, and where the alkyl, alkenyl and aryl groups may bear at least one substituent selected from the class consisting of hydroxyl, alkoxy, alkoxycarbonyl and NE1E2, where E1 and E2 may be identical or different and are hydrogen, alkyl or acyl, to the use of acylated polyamines for modifying the surface properties of solids, and also to a process for modifying the surface properties of particulate, linear, sheet-like, or three-dimensional structures.

Abstract: The invention relates to a method of in vitro testing of the efficacy of a potentially active substance comprising monitoring the effect of said potentially active substance on an artificial skin, comprising a composite product forming a collagen support comprising at least one porous collagen layer covered on at least one side with a collagen membrane component selected from the group consisting of a collagen membrane prepared by compression of a collagen sponge at a pressure of at least about 50 bar and of a collagen membrane comprising a collagen film prepared by drying a collagen gel separately from the porous collagen layer, thereby providing a reliable method for finding new potentially active substances.

Abstract: The invention relates to novel hydrated lamellar phases or liposomes which contain either polyethylenimine, or a substance which stimulates intracellular penetration selected from the group consisting of: i) a fatty monoamine of carbon-containing chain length of between C10 and C18; ii) a cationic polymer, optionally at least one fluorescent compound which is essentially inert with respect to the intracellular penetration, which enables this penetration to be visualised. These liposomes are very useful in cosmetics or in pharmacy for stimulating the intracellular penetration of a substance or active principle.

Abstract: The present invention relates to the formation of surface treated zinc oxide and titania particles, and in particular zinc oxide and titania nanoparticles, with a siloxane star-graft copolymer coating, comprising a looped and/or linear polymeric structure on a star-graft copolymer coating, on a particle surface to control the interfacial surface interactions between the particle and the oil phase of the cosmetic skin formulation.

Abstract: The invention relates to a method of in vitro testing of the efficacy of a potentially active substance comprising monitoring the effect of said potentially active substance on an artificial skin, comprising a composite product forming a collagen support comprising at least one porous collagen layer covered on at least one side with a collagen membrane component selected from the group consisting of a collagen membrane prepared by compression of a collagen sponge at a pressure of at least about 50 bar and of a collagen membrane comprising a collagen film prepared by drying a collagen gel separately from the porous collagen layer, thereby providing a reliable method for finding new potentially active substances.

Abstract: The invention relates to the use of CD14+ monocytes for the production of dendritic cells. The invention comprises the use of CD14+ monocytes isolated from peripheral circulating blood for obtaining, by differentiation, at least one mixed population of Langerhans cells and interstitial dendritic cells, both Langerhans cells and interstitial dendritic cells being preconditioned and undifferentiated, and/or differentiated and immature, and/or mature, and/or interdigitated. The invention comprises their use in suspension, monolayer and three-dimensional cell and tissue models. The invention comprises the use of these cells and of these models as study models for the assessment of immunotoxicity/immunotolerance, for the development of cosmetic and pharmaceutical active principles and for the development and implementation of methods of cell and tissue therapy.

Abstract: The invention relates to the stimulation of the activity of an isoform of lysyl oxidase, and more particularly of the LOX (lysyl oxidase) isoform.

Abstract: The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (Iysyl oxidase-like) isoform.

Abstract: A composite product is disclosed as a collagen support comprising at least one porous collagen layer covered on at least one side with an essentially compact collagen membrane consisting either of a collagen film prepared by drying a collagen gel, preferably in air or a gaseous fluid, or of a very highly compressed collagen sponge. At least one of the two layers, i.e. the porous layer and the essentially compact membrane, may comprise normal, genetically modified or malignant living cells originating particularly from young or elderly subjects. This composite product is used as a collagen support for the manufacture of artificial skin intended especially for performing in vitro tests on the efficacy of potentially active substances or for reconstructing damaged areas of skin in vivo.

Abstract: The present invention relates to particulate, linear, sheet-like, or three-dimensional structures which comprise, at least on their surface, a hydrophilicizing amount of at least one polymer which has urethane groups and/or urea groups, and also anionic groups.