Patents by Inventor Valdas Jurkauskas

Valdas Jurkauskas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CO-CRYSTALS AND PHARMACEUTICAL FORMULATIONS COMPRISING THE SAME
    Publication number: 20110236478
    Abstract: An immediate release formulation of an active ingredient.
    Type: Application
    Filed: February 24, 2011
    Publication date: September 29, 2011
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Eleni Dokou, Rahela Gasparac, Dragutin Knezic, Billie J. Kline, Valdas Jurkauskas
  • Co-Crystals and Pharmaceutical Compositions Comprising the Same
    Publication number: 20110059987
    Abstract: The invention relates to compositions and co-crystals each comprising VX-950 and a co-crystal former selected from the group consisting of 4-hydroxybenzoic acid, 4-amino salicylic acid, phenylalanine, threonline, tartaric acid, adipic acid, succinic acetate, proline, methyl 4-hydroxybenzoate, anthranilic acid, and d-Biotin. Also within the scope of this invention are methods of making and using the same.
    Type: Application
    Filed: February 27, 2008
    Publication date: March 10, 2011
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Patrick R. Connelly, Irina Kadiyala, Kathy Stavropolus, Yuegang Zhang, Steve Johnston, Govinda Rao Bhisetti, Valdas Jurkauskas, Peter Rose
  • Processes and intermediates
    Patent number: 7776887
    Abstract: The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
    Type: Grant
    Filed: August 18, 2006
    Date of Patent: August 17, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Minzhang Chen, John E. Cochran, Valdas Jurkauskas
  • Processes and intermediates
    Publication number: 20100174077
    Abstract: The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 8, 2010
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Minzhang Chen, John E. Cochran, Valdas Jurkauskas
  • PROCESSES AND INTERMEDIATES
    Publication number: 20100063252
    Abstract: The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
    Type: Application
    Filed: April 27, 2009
    Publication date: March 11, 2010
    Inventors: Gerald J. Tanoury, Minzhang Chen, John E. Cochran, Adam Looker, Valdas Jurkauskas
  • Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
    Publication number: 20050065349
    Abstract: One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, the transition metal catalyst consists essentially of copper and an asymmetric bidentate bisphosphine ligand.
    Type: Application
    Filed: September 7, 2004
    Publication date: March 24, 2005
    Inventors: Stephen Buchwald, Daniel Appella, Yasunori Moritani, Ryo Shintani, Valdas Jurkauskas
  • Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
    Patent number: 6787655
    Abstract: One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, the transition metal catalyst consists essentially of copper and an asymmetric bidentate bisphosphine ligand.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: September 7, 2004
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen L. Buchwald, Daniel H. Appella, Yasunori Moritani, Ryo Shintani, Valdas Jurkauskas
  • Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
    Publication number: 20030125563
    Abstract: One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, the transition metal catalyst consists essentially of copper and an asymmetric bidentate bisphosphine ligand.
    Type: Application
    Filed: October 15, 2002
    Publication date: July 3, 2003
    Inventors: Stephen L. Buchwald, Daniel H. Appella, Yasunori Moritani, Ryo Shintani, Valdas Jurkauskas
  • Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
    Patent number: 6465664
    Abstract: One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, the transition metal catalyst consists essentially of copper and an asymmetric bidentate bisphosphine ligand.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: October 15, 2002
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen L Buchwald, Daniel H. Appella, Yasunori Moritani, Ryo Shintani, Valdas Jurkauskas