Patents by Inventor Valentín Martínez Barrasa

Valentín Martínez Barrasa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRUG ANTIBODY CONJUGATES
    Publication number: 20240131180
    Abstract: Drug conjugates having formula [D-(X)b-(AA)w-(T)g-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, (I) wherein D is covalently attached via a hydroxy or amine group to (X)b if any, or (AA)w if any, or to (T)g if any, or (L); that are useful in the treatment of cancer.
    Type: Application
    Filed: April 21, 2021
    Publication date: April 25, 2024
    Inventors: Alfonso LATORRE LOZANO, Valentín MARTÍNEZ BARRASA, Andrés M. FRANCESCH SOLLOSO, María Del Carmen CUEVAS MARCHANTE
  • Antitumoral compounds
    Patent number: 11713325
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Grant
    Filed: April 5, 2022
    Date of Patent: August 1, 2023
    Assignee: Pharma Mar, S.A.
    Inventors: Maria del Carmen Cuevas Marchante, Andres Francesch Solloso, Valentin Martinez Barrasa
  • ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES
    Publication number: 20230012681
    Abstract: Drug conjugates having formula [D-(X)6-(AA)w-(T)g-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, (I) wherein D is covalently attached via a hydroxy or amine group to (X)b if any, or (AA)w if any, or to (T)g if any, or (L); that are useful in the treatment of cancer.
    Type: Application
    Filed: October 25, 2019
    Publication date: January 19, 2023
    Inventors: Maria del Carmen Ceuvas Marchante, Andres M. Franoesch Solioso, Alfonso Latorre Lozano, Valentin Martinez Barrasa
  • Antitumoral Compounds
    Publication number: 20220242883
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Application
    Filed: April 5, 2022
    Publication date: August 4, 2022
    Inventors: María del Carmen Cuevas Marchante, Andres Francesch Solloso, Valentin Martinez Barrasa
  • Antitumoral compounds
    Patent number: 11339180
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: May 24, 2022
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Antitumoral compounds
    Patent number: 11332480
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: May 17, 2022
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • ANTITUMORAL COMPOUNDS
    Publication number: 20210246146
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Application
    Filed: April 2, 2021
    Publication date: August 12, 2021
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Antitumoral Compounds
    Publication number: 20210070775
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Application
    Filed: April 27, 2018
    Publication date: March 11, 2021
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Antitumoral compounds
    Patent number: 10538535
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: January 21, 2020
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Antitumoral compounds
    Patent number: 10442820
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: October 15, 2019
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Antitumoral Compounds
    Publication number: 20180312529
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Application
    Filed: April 27, 2018
    Publication date: November 1, 2018
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Synthesis of naturally occuring ecteinascidins and related compounds
    Patent number: 7947671
    Abstract: Ecteinascidin compounds with a quinone ring for ring E are active as anti-cancer agents. Related processes and compounds are provided.
    Type: Grant
    Filed: April 12, 2010
    Date of Patent: May 24, 2011
    Assignee: Pharma Mar, S.A.
    Inventors: Valentin Martinez Barrasa, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares, Roberto Menchaca, Natividad Rodriguez, Alberto Rodriguez
  • Synthesis of naturally occurring ecteinascidins and related compounds
    Patent number: 7795260
    Abstract: Ecteinascidin compounds with a quinone ring for ring E are active as anti-cancer agents. Related processes and compounds are provided.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: September 14, 2010
    Assignee: Pharma Mar, S.A.
    Inventors: Valentin Martinez Barrasa, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares, Roberto Menchaca, Natividad Rodriguez, Alberto Rodriguez
  • SYNTHESIS OF NATURALLY OCCURING ECTEINASCIDINS AND RELATED COMPOUNDS
    Publication number: 20100216987
    Abstract: Ecteinascidin compounds with a quinone ring for ring E are active as anti-cancer agents. Related processes and compounds are provided.
    Type: Application
    Filed: April 12, 2010
    Publication date: August 26, 2010
    Inventors: Valentin Martinez Barrasa, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares, Roberto Menchaca, Natividad Rodriguez, Alberto Rodriguez
  • Synthesis of naturally occurring ecteinascidins and related compounds
    Patent number: 7767659
    Abstract: Ecteinascidin compounds with a quinone ring for ring E are active as anti-cancer agents. Related processes and compounds are provided.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: August 3, 2010
    Assignee: Pharma Mar, S.A.
    Inventors: Valentin Martinez Barrasa, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares, Roberto Menchaca, Natividad Rodriguez, Alberto Rodriguez
  • SYNTHESIS OF NATURALLY OCCURING ECTEINASCIDINS AND RELATED COMPOUNDS
    Publication number: 20090163507
    Abstract: Ecteinascidin compounds with a quinone ring for ring E are active as anti-cancer agents. Related processes and compounds are provided.
    Type: Application
    Filed: November 19, 2008
    Publication date: June 25, 2009
    Applicant: PHARMA MAR, S.A.
    Inventors: Valentin Martinez Barrasa, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares, Roberto Menchaca, Natividad Rodriguez, Alberto Rodriguez