Patents by Inventor Valentin Gorboulev

Valentin Gorboulev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucose sensor
    Patent number: 7238708
    Abstract: Methods are provided for the modulation of hSGLT3 protein glucosensor activity. The sensor is expressed in cholinergic neurons that regulate muscle activity, and in tissues including the brain and pacreas. The present invention also provides methods of identifying therapeutic compounds that modify the function of these sensors. Such therapeutic compounds have a functional effect on regulators of muscle activity, including gastrointestinal smooth muscles; on regulation of weight and metabolism; regulation of pancreatic function, including glucagons release; and in taste perception.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: July 3, 2007
    Assignee: The Regents of the University of California
    Inventors: Ernest M. Wright, Ana Diez-Sampedro, Bruce A. Hirayama, Hermann Koepsell, Valentin Gorboulev, Christina Osswald
  • Novel glucose sensor
    Publication number: 20050267154
    Abstract: Methods are provided for the modulation of hSGLT3 protein glucosensor activity. The sensor is expressed in cholinergic neurons that regulate muscle activity, and in tissues including the brain and pacreas. The present invention also provides methods of identifying therapeutic compounds that modify the function of these sensors. Such therapeutic compounds have a functional effect on regulators of muscle activity, including gastrointestinal smooth muscles; on regulation of weight and metabolism; regulation of pancreatic function, including glucagons release; and in taste perception.
    Type: Application
    Filed: March 10, 2005
    Publication date: December 1, 2005
    Inventors: Ernest Wright, Ana Diez-Sampedro, Bruce Hirayama, Hermann Koepsell, Valentin Gorboulev, Christina Osswald
  • Transport protein which effects the transport of cationic xenobiotics and/or pharmaceuticals, DNA sequences encoding it and their use
    Patent number: 6063766
    Abstract: A transport protein has been cloned which is present in liver epithelial cells and kidney epithelial cells and in intestinal cells and is responsible for transporting cationic pharmaceuticals and/or xenobiotics. This transport protein has been described more specifically by its DNA and amino acid sequences, and various uses are disclosed which are, in particular, of great importance for developing novel medicaments.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: May 16, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hermann Koepsell, Dirk Grundemann, Valentin Gorboulev
  • Transport protein which effects the transport of cationic xenobiotics and/or pharmaceuticals, DNA sequences encoding it and their use
    Patent number: 6063623
    Abstract: A transport protein has been cloned which is present in liver epithelial cells and kidney epithelial cells and in intestinal cells and is responsible for transporting cationic pharmaceuticals and/or xenobiotics. This transport protein has been described more specifically by its DNA and amino acid sequences, and various uses are disclosed which are, in particular, of great importance for developing novel medicaments.
    Type: Grant
    Filed: July 12, 1995
    Date of Patent: May 16, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hermann Koepsell, Dirk Grundemann, Valentin Gorboulev