Patents by Inventor Valentin Martinez

Valentin Martinez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antitumoral derivatives of ET-743
    Patent number: 8076337
    Abstract: Derivatives of Et-743 or Et-770 or Et-729 are provided. The derivatives are of the general formula Ia.: wherein the substituent groups take various permitted meanings.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: December 13, 2011
    Assignee: Pharma Mar, S.A.
    Inventors: Valentin Martinez, Maria Flores, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares
  • ANTITUMORAL DERIVATIVES OF ET-743
    Publication number: 20100197695
    Abstract: Derivatives of Et-743 or Et-770 or Et-729 are provided. The derivatives are of the general formula Ia.: wherein the substituent groups take various permitted meanings.
    Type: Application
    Filed: April 6, 2010
    Publication date: August 5, 2010
    Inventors: Valentin Martinez, Maria Flores, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares
  • Ecteinascidin analogs for use as antitumour agents
    Patent number: 7763615
    Abstract: Derivatives of ecteinascidin 736 of general formula (I) wherein the groups R1, R2, R3, R4 and R5 are each independently selected from the group consisting of H, OH, OR?, SH, SR?, SOR?, SO2R?, C(?O)R?, C(?O)OR?, NO2, NH2, NHR?, N(R?)2, NHC(O)R?, CN, halogen, ?O, substituted or unsubstituted C1-C25 alkyl, substituted or unsubstituted C2-C18 alkenyl, substituted or unsubstituted C2-C18 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heterocyclic; wherein X is independently selected of OR?, CN, (?O), or H; wherein each of the R? groups is independently selected from the group consisting of H, OH, NO2, NH2, SH, CN, halogen, ?O, C(?O)H, C(?O)CH3, CO2H, substituted or unsubstituted C1-C25 alkyl, substituted or unsubstituted C2-C18 alkenyl, substituted or unsubstituted C2-C18 alkynyl, substituted or unsubstituted aryl; wherein m is 0, 1 or 2; and wherein n is 0, 1, 2, 3, or 4, and their use as antitumoral agent.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: July 27, 2010
    Assignee: Pharma Mar, S.A.
    Inventors: Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares, Valentin Martinez
  • Antitumoral derivatives of ET-743
    Patent number: 7759345
    Abstract: Derivatives of Et-743 or Et-770 or Et-729 are provided. The derivatives are of the general formula (Ia) wherein the substituent groups take various permitted meanings.
    Type: Grant
    Filed: July 17, 2002
    Date of Patent: July 20, 2010
    Assignee: Pharma Mar, S.A.
    Inventors: Valentin Martinez, Maria Flores, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares
  • Synthesis of naturally occcuring ecteinascidins and related compounds
    Publication number: 20070093658
    Abstract: Ecteinascidin compounds with a quinone ring for ring E are active as anti-cancer agents. Related processes and compounds are provided.
    Type: Application
    Filed: February 4, 2003
    Publication date: April 26, 2007
    Applicant: Pharma Mar, S.A.
    Inventor: Valentin Martinez
  • Antitumoral analogs
    Publication number: 20060128711
    Abstract: Derivatives of ecteinascidin 736 of general formula (I) wherein the groups R1, R2, R3, R4 and R5 are each independently selected from the group consisting of H, OH, OR?, SH, SR?, SOR?, SO2R?, C(?O)R?, C(?O)OR?, NO2, NH2, NHR?, N(R?)2, NHC(O)R?, CN, halogen, ?O, substituted or unsubstituted C1-C25 alkyl, substituted or unsubstituted C2-C18 alkenyl, substituted or unsubstituted C2-C18 alkynyl, substituted or unsubstituted arly, substituted or unsubstituted heterocyclic; wherein X is independently selected of OR?, CN, (?O), or H; wherein each of the R? groups is independently selected from the group consisting of H, OH, NO2, NH2, SH, CN, halogen, ?O, C(?O)H, C(?O)CH3, CO2H, substituted or unsubstituted C1-C25 alkyl, substituted or unsubstituted C1-C18 alkenyl, substituted or unsubstituted C2-C18 alkynyl, substituted or unsubstituted aryl; wherein m is 0, 1 or 2; and wherein n is 0, 1, 2, 3, or 4, and their use as antitumoral agent.
    Type: Application
    Filed: August 6, 2002
    Publication date: June 15, 2006
    Inventors: Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares, Valentin Martinez
  • New antitumoral derivatives of et-743
    Publication number: 20060106021
    Abstract: Derivatives of Et-743 or Et-770 or Et-729 are provided. The derivatives are of the general formula (Ia) wherein the substituent groups take various permitted meanings.
    Type: Application
    Filed: July 17, 2002
    Publication date: May 18, 2006
    Inventors: Valentin Martinez, Maria Flores, Pilar Gallego, Carmen Cuevas, Simon Munt, Ignacio Manzanares