Patents by Inventor Valentina CANEVARI

Valentina CANEVARI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PURIFICATION OF MELPHALAN
    Publication number: 20170226047
    Abstract: A method for the purification and preparation of melphalan that allows to obtain melphalan with purity higher than 99.5% is described.
    Type: Application
    Filed: April 27, 2017
    Publication date: August 10, 2017
    Inventors: Claudio Gianluca POZZOLI, Valentina CANEVARI, Matteo Curti
  • Process for the purification of melphalan
    Patent number: 9663450
    Abstract: A method for the purification and preparation of melphalan that allows to obtain melphalan with purity higher than 99.5% is described.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: May 30, 2017
    Assignee: FARMABIOS S.P.A.
    Inventors: Claudio Gianluca Pozzoli, Valentina Canevari, Matteo Curti
  • PROCESS FOR THE PURIFICATION OF MELPHALAN
    Publication number: 20160090352
    Abstract: A method for the purification and preparation of melphalan that allows to obtain melphalan with purity higher than 99.5% is described.
    Type: Application
    Filed: May 27, 2014
    Publication date: March 31, 2016
    Inventors: Claudio Gianluca POZZOLI, Valentina CANEVARI, Matteo Curti
  • Synthesis of nucleosides
    Patent number: 9109000
    Abstract: A process for the preparation of nucleosides, derivatives and analogues thereof by coupling reaction of a protected suitable nitrogeneous purine or pyrimidine base, a derivative or analogue thereof and a protected suitable sugar in the presence of SnCl4 comprising the removal of SnCl4 by adding DMSO directly into the reaction mixture is described. Preferably said process is used for the preparation of antiviral and antitumor agents having a nucleoside or nucleoside-like structure, still more preferably for the preparation of azacytidine, decitabine, chlorfarabine, cladribine, mizoribine. A residual tin content lower than 300 ppm is obtained with said process.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: August 18, 2015
    Assignee: FARMABIOS, S.p.A.
    Inventors: Claudio Gianluca Pozzoli, Valentina Canevari, Marco Brusasca, Lorenzo Menna, Matteo Curti
  • SYNTHESIS OF NUCLEOSIDES
    Publication number: 20140135490
    Abstract: A process for the preparation of nucleosides, derivatives and analogues thereof by coupling reaction of a protected suitable nitrogeneous purine or pyrimidine base, a derivative or analogue thereof and a protected suitable sugar in the presence of SnCl4 comprising the removal of SnCl4 by adding DMSO directly into the reaction mixture is described. Preferably said process is used for the preparation of antiviral and antitumor agents having a nucleoside or nucleoside-like structure, still more preferably for the preparation of azacytidine, decitabine, chlorfarabine, cladribine, mizoribine. A residual tin content lower than 300 ppm is obtained with said process.
    Type: Application
    Filed: October 25, 2013
    Publication date: May 15, 2014
    Applicant: FARMABIOS S.p.A.
    Inventors: Claudio Gianluca POZZOLI, Valentina CANEVARI, Marco BRUSASCA, Lorenzo MENNA, Matteo CURTI