Patents by Inventor Valentina Di Francesco

Valentina Di Francesco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated human protese proteins, nucleic acid molecules encoding human protease proteins and uses thereof
    Patent number: 7029901
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the protease peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the protease peptides, and methods of identifying modulators of the protease peptides.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: April 18, 2006
    Assignee: Applera Corporation
    Inventors: Weiniu Gan, Jane Ye, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 7005286
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: February 28, 2006
    Assignee: Applera Corporation
    Inventors: Jane Abu-Threideh, Fangcheng Gong, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6991928
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: January 31, 2006
    Assignee: Applera Corporation
    Inventors: Ming-Hui Wei, Shiaoping Zhu, Trevor Woodage, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human transporter proteins, nucleic acid molecules, encoding human transporter proteins, and uses thereof
    Patent number: 6991920
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: January 31, 2006
    Assignee: Applera Corporation
    Inventors: Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated nucleic acid molecules encoding human drug metabolizing proteins
    Patent number: 6987014
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: January 17, 2006
    Assignee: Applera Corporation
    Inventors: Ming-Hui Wei, Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6984511
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: January 10, 2006
    Assignee: Applera Corporation
    Inventors: Marion Webster, Chunhua Yan, Valentina Di Francesco, Ellen Beasley
  • Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
    Patent number: 6969588
    Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: November 29, 2005
    Assignee: Applera Corporation
    Inventors: Beena Neelam, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
    Patent number: 6967094
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the proteins of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the proteins of the present invention, and methods of identifying modulators of the proteins of the present invention.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: November 22, 2005
    Assignee: Applera Corporation
    Inventors: Trevor Woodage, Ming-Hui Wei, Chinnappa Kodira, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
    Publication number: 20050250154
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the protease peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the protease peptides, and methods of identifying modulators of the protease peptides.
    Type: Application
    Filed: July 18, 2005
    Publication date: November 10, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Weiniu Gan, Jane Ye, Valentina Di Francesco, Ellen Beasley
  • Methods and systems for identifying genes, splice variants, and transcripts using an evidence mapping approach
    Publication number: 20050246106
    Abstract: The present teachings contain a method and system for gene and splice variant identification and display. The teachings employ evidence from various genomic and proteomic databases. The method can be run on a computer system and performs its function by mapping evidence to a genome under study and then collapsing overlapping evidence to form clusters. Various rules are taught that can be used to identify unique transcripts and gene boundaries. Clusters can be displayed visually or in report format. Regardless of format, the evidence leading the cluster definitions can be seen.
    Type: Application
    Filed: September 20, 2004
    Publication date: November 3, 2005
    Applicant: Applera Corporation
    Inventors: Chunlin Xiao, Valentina Di Francesco, Brian Walenz, Peter Li, Michael Campbell, Liliana Florea
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Publication number: 20050244833
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Application
    Filed: September 17, 2003
    Publication date: November 3, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Ming-Hui Wei, Kabir Chaturvedi, Valentina Di Francesco, Ellen Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Publication number: 20050239168
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Application
    Filed: June 7, 2005
    Publication date: October 27, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Ming-Hui Wei, Karen Ketchum, Ellen Beasley, Valentina Di Francesco
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6955625
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: October 18, 2005
    Assignee: Applera Corporation
    Inventors: Ellen M. Beasley, Wei Shao, Karen A. Ketchum, Valentina Di Francesco
  • Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
    Patent number: 6953681
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the proteins of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the proteins of the present invention, and methods of identifying modulators of the proteins of the present invention.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: October 11, 2005
    Assignee: Applera Corporation
    Inventors: Trevor Woodage, Ming-Hui Wei, Chinnappa Kodira, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human ras- like proteins, nucleic acid molecules encoding these human ras-like proteins , and uses thereof
    Publication number: 20050222018
    Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
    Type: Application
    Filed: March 28, 2002
    Publication date: October 6, 2005
    Inventors: Chunhua Yan, Jane Ye, Valentina Di Francesco, Ellen Beasley
  • Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
    Publication number: 20050221437
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
    Type: Application
    Filed: May 25, 2005
    Publication date: October 6, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Rhonda Brandon, Valentina Di Francesco, Ellen Beasley
  • Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
    Publication number: 20050214829
    Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
    Type: Application
    Filed: January 28, 2005
    Publication date: September 29, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Wei Shao, Gennady Merkulov, Valentina Di Francesco, Ellen Beasley
  • Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
    Patent number: 6949371
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: September 27, 2005
    Assignee: Applera Corporation
    Inventors: Gennady V. Merkulov, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
  • Isolated human aminoacylase, nucleic acid molecules encoding human aminoacylase, and uses thereof
    Publication number: 20050208578
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
    Type: Application
    Filed: May 23, 2005
    Publication date: September 22, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Wei Shao, Chunhua Yan, Valentina Di Francesco, Ellen Beasley
  • Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
    Publication number: 20050208563
    Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
    Type: Application
    Filed: April 29, 2005
    Publication date: September 22, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Gennady Merkulov, Valentina Di Francesco, Ellen Beasley