Patents by Inventor Valentina Fiori

Valentina Fiori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY COMPLEX AND USES THEREOF
    Publication number: 20210230292
    Abstract: The present invention relates to a multivalent, preferably bivalent, antibody complex, more preferably a diabody, i.e. a bivalent scFv, capable of recognizing and binding the human protein CD99, a composition comprising said complex and the use thereof for diagnostic purposes and/or for the treatment and/or the follow-up of leukaemias and/or myelodysplastic syndromes. Furthermore, the present invention relates to antibodies, preferably monoclonal, of the immunoglobulins G group type capable of recognizing and binding the human protein CD99, a composition comprising said immunoglobulins and the medical use thereof, in particular for the treatment and/or the follow-up of cancer, preferably solid tumours that express CD99 and/or leukaemias and/or myelodysplastic syndromes.
    Type: Application
    Filed: June 3, 2019
    Publication date: July 29, 2021
    Applicant: DIATHEVA S.R.L.
    Inventors: Valentina FIORI, Sabrina DOMINICI, Diego MORICOLI, Maria Elena LAGUARDIA, Cosimo Damiano CARBONELLA, Maria Cristina BALDUCCI
  • Antibody derivatives
    Patent number: 8822648
    Abstract: An anti-CEA scFv having an uncleaved Pel B leader sequence is surprisingly stable and is highly specific for CEA and CEACAM1.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: September 2, 2014
    Assignees: Instituto Superiore di Sanita, Diatheva s.r.l.
    Inventors: Maurizio Cianfriglia, Michela Flego, Alessandro Ascione, Valentina Fiori, Sabrina Domicini, Alessandra Mallano, Diego Moricoli, Silvia Zamboni