Patents by Inventor Valentina Grande

Valentina Grande has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of apalutamide
    Patent number: 11820752
    Abstract: The present invention relates to a process for the preparation of Apalutamide of formula (A) Apalutamide is a latest-generation androgen receptor inhibitor, used to treat non-metastatic castration-resistant prostate cancer.
    Type: Grant
    Filed: May 27, 2019
    Date of Patent: November 21, 2023
    Assignee: OLON S.P.A.
    Inventors: Valentina Grande, Gabriele Ferretti, Barbara Novo
  • STABLE CRYSTALLINE APALUTAMIDE IN PURE FORM, AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20220324831
    Abstract: The present invention relates to a novel non-solvated crystalline form of apalutamide in pure, stable form, and the process for the preparation thereof.
    Type: Application
    Filed: September 7, 2020
    Publication date: October 13, 2022
    Applicant: OLON S.P.A.
    Inventors: Valentina Grande, Alessia Manfredi, Jacopo Bonanomi, Gabriele Ferretti, Barbara Novo, Mara Sada, Giorgio Bertolini
  • SYNTHESIS OF STABLE AMORPHOUS APALUTAMIDE
    Publication number: 20220153718
    Abstract: The present invention relates to a process for the preparation of apalutamide in stable amorphous form. The invention also relates to a novel intermediate crystalline form, called form X, which gives rise to said amorphous form, and a process for obtaining said form X.
    Type: Application
    Filed: March 9, 2020
    Publication date: May 19, 2022
    Applicant: OLON S.P.A.
    Inventors: Valentina Grande, Barbara Novo, Mara SADA, Gabriele Ferretti, Alessia Manfredi
  • PROCESS FOR THE PREPARATION OF APALUTAMIDE
    Publication number: 20210206742
    Abstract: The present invention relates to a process for the preparation of Apalutamide of formula (A) Apalutamide is a latest-generation androgen receptor inhibitor, used to treat non-metastatic castration-resistant prostate cancer.
    Type: Application
    Filed: May 27, 2019
    Publication date: July 8, 2021
    Applicant: OLON S.P.A.
    Inventors: Valentina Grande, Gabriele Ferretti, Barbara Novo