Patents by Inventor Valentina POLETTI

Valentina POLETTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW PROMOTER SEQUENCE FOR GENE THERAPY
    Publication number: 20240226333
    Abstract: The present invention relates to a promoter sequence for efficient and sufficient expression of transgenes as well as to gene transfer vectors comprising said promoter sequence for use in therapy. In particular, the present invention relates to lentiviral vectors that provide gene therapy for pathological conditions of the central nervous system.
    Type: Application
    Filed: May 3, 2022
    Publication date: July 11, 2024
    Applicant: UNIVERSITÁ DEGLI STUDI DI PADOVA
    Inventors: Alessandra BIFFI, Valentina POLETTI
  • MICROGLIA SPECIFIC PROMOTERS AND METHODS OF USE THEREFORE
    Publication number: 20220348962
    Abstract: The present disclosure features methods and compositions for expressing transgenes in microglia. The disclosed compositions comprise isolated fragments of human and murine translocator protein (TSPO) promoters and expression cassettes comprising the same. The methods involve using these promoters and/or expression cassettes to express transgenes in a cell.
    Type: Application
    Filed: October 1, 2020
    Publication date: November 3, 2022
    Applicants: Children's Medical Center Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Alessandra BIFFI, Valentina POLETTI, Marco PEVIANI, Francisco J. MOLINA-ESTEVEZ