Patents by Inventor Valentine Brousse

Valentine Brousse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR SCREENING COMPOUNDS FOR THEIR ABILITY TO INCREASE RIGIDITY OF RED BLOOD CELLS INFECTED BY A PROTOZOAN PARASITE OF THE GENUS PLASMODIUM, METHOD FOR FILTERING RED BLOOD CELLS, AND APPLICATION THEREOF
    Publication number: 20110230369
    Abstract: The invention relates to a method for screening compounds for their ability to increase rigidity of red blood cells (RBCs) infected by a protozoan parasite of the genus Plasmodium and in particular by Plasmodium falciparum. The present invention also relates to a method for filtering RBCs that enables retention, in a filtering unit, of RBCs having an abnormal and in particular a decreased deformability, as a surrogate for spleen filtering function. Said method enables in particular isolating and/or detecting Plasmodium-infected RBCs or spherocytes associated with acquired or hereditary spherocytosis from a sample of blood from a patient, or analysing in vitro spleen function of a patient.
    Type: Application
    Filed: May 28, 2009
    Publication date: September 22, 2011
    Inventors: Pierre Antoine Buffet, Guillaume Deplaine, Gencvièvc Milon, Peter David, Innocent Safeukui Noubissi, Sylvie Perrot, Valentine Brousse, Narla Mohandas, Francois Lacoste, Odile Puijalon