Abstract: A method and kit are provided for visualization of a latent pattern of molecular structures on a substrate surface. The method is comprised of developing the substrate in a solution of colloidal particles. A detectable change on the substrate surface is brought about as a result of the precipitation of the colloidal particles. The invention also provides compositions and kits for practicing the method of the present invention. Further, the invention provides methods of capturing images of the substrate surface for visualization and quantification of the molecular structures.

Abstract: A method and apparatus are provided for identifying molecular structures within a sample substance using an integrated circuit array sensor having a plurality of test sites upon which the sample substance is applied. Each test site includes a probe formed therein to bond with an associated target molecular structure. An electrical signal produced on the test site upon forming or breaking of molecular probe-target duplexes is detected to determine which probes have bonded to an associated target molecular structure.