Patents by Inventor Valeria Alcon

Valeria Alcon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant Bacterium and Uses Thereof
    Publication number: 20170174746
    Abstract: The present invention relates to a recombinant bacterium expressing an antigen that is translocated to the cytosol of a host organism, and uses thereof. To this end, the present invention provides a recombinant bacterium comprising a nucleic acid encoding an antigen that is translocated to the cytosol of a host cell utilizing Type Ill secretion system. The recombinant bacterium is generally chosen from intracellular pathogens that reside in the phagosome and fail to induce rapid T cell activation. The translocated antigen may be a viral antigen, a bacterial antigen, or a tumour antigen. Methods of imparting immunity using the recombinant bacterium are also provided.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 22, 2017
    Applicant: National Research Council of Canada
    Inventors: Subash Sad, Lakshmi Krishnan, Fanny Tzelepis, Valeria Alcon, Kevin G. Young
  • Recombinant bacterium and uses thereof
    Patent number: 9539313
    Abstract: The present invention relates to a recombinant bacterium expressing an antigen that is translocated to the cytosol of a host organism, and uses thereof. To this end, the present invention provides a recombinant bacterium comprising a nucleic acid encoding an antigen that is translocated to the cytosol of a host cell utilizing Type III secretion system. The recombinant bacterium is generally chosen from intracellular pathogens that reside in the phagosome and fail to induce rapid T cell activation. The translocated antigen may be a viral antigen, a bacterial antigen, or a tumor antigen. Methods of imparting immunity using the recombinant bacterium are also provided.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: January 10, 2017
    Assignee: National Research Council of Canada
    Inventors: Subash Sad, Lakshmi Krishnan, Fanny Tzelepis, Valeria Alcon, Kevin G. Young
  • Recombinant Bacterium and Uses Thereof
    Publication number: 20150140028
    Abstract: The present invention relates to a recombinant bacterium expressing an antigen that is translocated to the cytosol of a host organism, and uses thereof. To this end, the present invention provides a recombinant bacterium comprising a nucleic acid encoding an antigen that is translocated to the cytosol of a host cell utilizing Type III secretion system. The recombinant bacterium is generally chosen from intracellular pathogens that reside in the phagosome and fail to induce rapid T cell activation. The translocated antigen may be a viral antigen, a bacterial antigen, or a tumour antigen. Methods of imparting immunity using the recombinant bacterium are also provided.
    Type: Application
    Filed: October 16, 2014
    Publication date: May 21, 2015
    Inventors: Subash SAD, Lakshmi KRISHNAN, Fanny TZELEPIS, Valeria ALCON, Kevin G. YOUNG
  • Recombinant Bacterium and Uses Thereof
    Publication number: 20130156809
    Abstract: The present invention relates to a recombinant bacterium expressing an antigen that is translocated to the cytosol of a host organism, and uses thereof. To this end, the present invention provides a recombinant bacterium comprising a nucleic acid encoding an antigen that is translocated to the cytosol of a host cell utilizing Type III secretion system. The recombinant bacterium is generally chosen from intracellular pathogens that reside in the phagosome and fail to induce rapid T cell activation. The translocated antigen may be a viral antigen, a bacterial antigen, or a tumour antigen. Methods of imparting immunity using the recombinant bacterium are also provided.
    Type: Application
    Filed: July 28, 2011
    Publication date: June 20, 2013
    Inventors: Subash Sad, Lakshmi Krishnan, Valeria Alcon, Kevin G. Young, Fanny Tzelepis