Patents by Inventor Valeria Di Bussolo

Valeria Di Bussolo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDOLE DERIVATIVES INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH)
    Publication number: 20140343001
    Abstract: The present invention encompasses compounds having general formula (I) able to inhibit the lactate production (lactic acid) involved in the angiogenesis of tumoral tissues, in the glycolytic metabolic process of tumoral cells, of immune system cells in asthmatic diseases, in vascular cells in the pulmonary hypertension, in the treatment of chronic back pain or hyperoxaluria, and in the process by which the parasites protozoan causing malaria obtain most of the necessary energy.
    Type: Application
    Filed: December 19, 2012
    Publication date: November 20, 2014
    Applicant: Universita di Pisa
    Inventors: Filippo Minutolo, Marco Macchia, Carlotta Granchi, Valeria Di Bussolo, Gino Giannaccini, Antonio Lucacchini, Paul J. Hergenrother, Emilia C. Calvaresi