Patents by Inventor Valerian B. Pinto

Valerian B. Pinto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multivalent meningococcal conjugates and methods for preparing conjugates
    Patent number: 9427476
    Abstract: Disclosed herein are meningococcal immunogenic conjugates which can elicit immune responses against meningococcal polysaccharides (PS) from groups A, C, W-135, and Y and group B factor H binding protein (fHbp). The disclosed conjugates also exhibit bactericidal activity against meningococcal A, C, W-135, Y, B, and X serogroups. Also disclosed are improved methods for preparing conjugates, such as immunogenic conjugates, including activation of a polysaccharide with a cyanylation agent at about 4° C.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: August 30, 2016
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The United States of America, as Represented by the Secretary of the Army
    Inventors: Che-Hung Robert Lee, Valerian B. Pinto
  • MULTIVALENT MENINGOCOCCAL CONJUGATES AND METHODS FOR PREPARING CONJUGATES
    Publication number: 20150110829
    Abstract: Disclosed herein are meningococcal immunogenic conjugates which can elicit immune responses against meningococcal polysaccharides (PS) from groups A, C, W-135, and Y and group B factor H binding protein (fHbp). The disclosed conjugates also exhibit bactericidal activity against meningococcal A, C, W-135, Y, B, and X serogroups. Also disclosed are improved methods for preparing conjugates, such as immunogenic conjugates, including activation of a polysaccharide with a cyanylation agent at about 4° C.
    Type: Application
    Filed: May 23, 2013
    Publication date: April 23, 2015
    Inventors: Che-Hung Robert Lee, Valerian B. Pinto