Patents by Inventor Valerie Autier

Valerie Autier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11369595
    Abstract: The present invention concerns a tryptophan metabolite chosen from kynurenic acid, anthranilic acid, quinolinic acid, picolinic acid, quinaldic acid and the mixtures of same or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt of same, for use as a drug intended for increasing and/or maintaining muscle mass and/or strength in a mammal, and in particular intended for treating and/or preventing muscle atrophy in mammals and/or for promoting muscle growth in mammals doing exercise and aiming to increase muscle mass and/or quality and/or strength, for preventing the appearance of symptoms of sarcopenia or for rehabilitation following muscle loss and/or for improving recovery time after an intense physical effort.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: June 28, 2022
    Assignee: METABRAIN RESEARCH
    Inventors: Sophie N. Raynal, Annick Audet, Valérie Autier, Christine Charon, Jean-Denis Durand, Micheline Kergoat
  • Publication number: 20190247385
    Abstract: The present invention concerns a tryptophan metabolite chosen from kynurenic acid, anthranilic acid, quinolinic acid, picolinic acid, quinaldic acid and the mixtures of same or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt of same, for use as a drug intended for increasing and/or maintaining muscle mass and/or strength in a mammal, and in particular intended for treating and/or preventing muscle atrophy in mammals and/or for promoting muscle growth in mammals doing exercise and aiming to increase muscle mass and/or quality and/or strength, for preventing the appearance of symptoms of sarcopenia or for rehabilitation following muscle loss and/or for improving recovery time after an intense physical effort.
    Type: Application
    Filed: September 5, 2017
    Publication date: August 15, 2019
    Applicant: METABRAIN RESEARCH
    Inventors: Sophie N. Raynal, Annick Audet, Valérie Autier, Christine Charon, Jean-Denis Durand, Micheline Kergoat
  • Patent number: 10350184
    Abstract: This invention relates to oxime and alkoxy derivatives of the general formula (I), or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof for use as a medicament for the treatment and/or prevention of muscle atrophy in mammals and/or for limiting muscular atrophy in mammals and/or to promote muscle growth in exercising mammals aimed at increasing muscle mass and quality, preventing the occurrence of symptoms of sarcopenia related to age or rehabilitation after a muscle loss, age-related muscle atrophy and/or the consequences of drug therapy and/or immobilization and/or cachexia.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: July 16, 2019
    Assignee: METABRAIN RESEARCH
    Inventors: Sophie N. Raynal, Micheline R. Kergoat, Valerie Autier, Christine G. Charon, Jean-Denis Durand, Franck F. Lepifre, Annick M. Audet
  • Publication number: 20180303780
    Abstract: This invention relates to a derivative of the general formula (I), as follows: or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof for use as a medicament for the treatment and/or prevention of muscle atrophy in mammals and/or for limiting muscular atrophy in mammals and/or to promote muscle growth in exercising mammals aimed at increasing muscle mass and quality, preventing the occurrence of symptoms of sarcopenia related to age or rehabilitation after a muscle loss, age-related muscle atrophy and/or the consequences of drug therapy and/or immobilization and/or cachexia.
    Type: Application
    Filed: April 14, 2016
    Publication date: October 25, 2018
    Inventors: Sophie N. RAYNAL, Micheline R. KERGOAT, Valerie AUTIER, Christine G. CHARON, Jean-Denis DURAND, Franck F. LEPIFRE, Annick M. AUDET
  • Patent number: 9777015
    Abstract: The present invention relates to a thiophene derivative of the following general formula I or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof or to its use as a drug in particular intended for treating and/or preventing diabetes, its complications and/or associated pathologies, advantageously diabetes of type II and hyperglycemia.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: October 3, 2017
    Assignee: METABRAIN RESEARCH
    Inventors: Franck F. Lepifre, Gersande R. Lena, Valerie Autier, Micheline R. Kergoat, Lauren R. Faveriel, Christine G. Charon, Sophie N. Raynal, Annick M. Audet
  • Patent number: 9381191
    Abstract: The present invention relates to imidazopyridine derivatives of the following general formula I: and to their use as a drug, in particular in treating and/or preventing diabetes, its complications and/or associated pathologies.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: July 5, 2016
    Assignee: METABRAIN RESEARCH
    Inventors: Franck F. Lepifre, Gersande R. Lena, Valerie Autier, Micheline R. Kergoat, Christine G. Charon, Sophie N. Raynal, Annick M. Audet
  • Publication number: 20150197530
    Abstract: The present invention relates to a thiophene derivative of the following general formula I or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof or to its use as a drug in particular intended for treating and/or preventing diabetes, its complications and/or associated pathologies, advantageously diabetes of type II and hyperglycemia.
    Type: Application
    Filed: July 16, 2013
    Publication date: July 16, 2015
    Inventors: Franck F. Lepifre, Gersande R. Lena, Valérie Autier, Micheline Kergoat, Lauren R. Faveriel, Christine G. Charon, Sophie N. Raynal, Annick M. Audet
  • Publication number: 20150182507
    Abstract: The present invention relates to imidazopyridine derivatives of the following general formula I: and to their use as a drug, in particular in treating and/or preventing diabetes, its complications and/or associated pathologies.
    Type: Application
    Filed: July 16, 2013
    Publication date: July 2, 2015
    Applicant: METABRAIN REDEARCH
    Inventors: Franck F. Lepifre, Gersande R. Lena, Valérie Autier, Micheline R. Kergoat, Christine G. Charon, Sophie N. Raynal, Annick M. Audet
  • Publication number: 20100273872
    Abstract: The present invention relates to the use of a 4-oxobutanoic acid derivative for the preparation of a pharmaceutical composition for the treatment of pathologies associated with immunological disorders.
    Type: Application
    Filed: November 6, 2008
    Publication date: October 28, 2010
    Inventors: Valerie Autier, Roland Fabregue, Patrick Miossec
  • Patent number: 7727977
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase for the preparation of a medicament for the prevention and/or treatment of diabetes.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: June 1, 2010
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Gérard Moinet, Dominique Mariais, Catherine Kargar, Micheline Kergoat
  • Publication number: 20060142358
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase for the preparation of a medicament for the prevention and/or treatment of diabetes.
    Type: Application
    Filed: December 18, 2003
    Publication date: June 29, 2006
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Micheline Kergoat, Gerard Moinet, Dominique Marais, Catherine Kargar
  • Publication number: 20060052456
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase, for the preparation of a medica ment for increasing the number of islets of Langerhans cells, which is intended especially for the prevention and/or treatment of diabetes.
    Type: Application
    Filed: December 18, 2003
    Publication date: March 9, 2006
    Applicant: MERCK PATENT GMBH
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Micheline Kergoat, Gerard Moinet, Dominique Marais, Catherine Kargar