Patents by Inventor Valerie Combaret

Valerie Combaret has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Determination of 17q Gain in Neuroblastoma Patients by Analysis of Circulating DNA
    Publication number: 20120220487
    Abstract: Methods for diagnosis of neuroblastoma comprising determining whether there is a gain of genetic material from chromosome arm segment 17q21-qter in the circulating DNA of a human subject.
    Type: Application
    Filed: November 2, 2010
    Publication date: August 30, 2012
    Applicant: CENTRE LEON BERARD
    Inventors: Alain Puisieux, Valérie Combaret
  • Treatment of neuroblastoma
    Publication number: 20070135444
    Abstract: 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof can be used in the treatment of neuroblastoma. The invention also relates to a combination of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof with one or more antineoplastic agents.
    Type: Application
    Filed: January 11, 2007
    Publication date: June 14, 2007
    Inventors: Renaud Capdeville, Valerie Combaret, Didier Frappaz, Alain Puisieux, Christophe Bergeron
  • Method for the diagnosis/prognosis of neuroblastoma
    Publication number: 20060263784
    Abstract: The present invention relates to a method for neuroblastoma prognosis in a patient suffering from neuroblastoma, characterized in that it comprises the following steps: a. biological material is extracted from a biological sample taken from the patient, b. the biological material is brought into contact with at least one specific reagent chosen from the reagents specific for the target genes exhibiting a nucleic acid sequence having any one of SEQ ID Nos. 1 to 37, it being understood that, when the target gene exhibits a nucleic acid sequence having one of SEQ ID Nos. 11, 17 or 37, the biological material is brought into contact with at least two specific reagents chosen from the reagents specific for the target genes exhibiting a nucleic acid sequence having any one of SEQ ID Nos. 1 to 37, c. the expression of at least one of said target genes is determined, it being understood that, when the target gene exhibits a nucleic acid sequence having one of SEQ ID Nos.
    Type: Application
    Filed: October 1, 2004
    Publication date: November 23, 2006
    Inventors: Valerie Combaret, Alexander Krause, Alain Puisieux, Bruno Lacroix
  • Treatment of neuroblastoma
    Publication number: 20050159426
    Abstract: 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof can be used in the treatment of neuroblastoma. The invention also relates to a combination of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutical acceptable salt thereof with one or more antineoplastic agents.
    Type: Application
    Filed: February 6, 2003
    Publication date: July 21, 2005
    Inventors: Renaud Capdeville, Valerie Combaret, Didier Frappaz, Alain Puisieux, Christophe Bergeron