Patents by Inventor Valerie L. Gerlach

Valerie L. Gerlach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6875570
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: April 5, 2005
    Assignee: CuraGen Corporation
    Inventors: Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, David Stone, Erik Gunther, Karen Ellerman, William M. Grosse, John P. Alsobrook, II, Denise M. Lepley, Catherine E. Burgess, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Martin D. Leach, Richard A. Shimkets
  • Publication number: 20040096877
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 21, 2003
    Publication date: May 20, 2004
    Inventors: Raymond J. Taupier, Muralidhara Padigaru, Luca Rastelli, Steven Kurt Spaderna, Richard A. Shimkets, Bryan D. Zerhusen, Kimberly Ann Spytek, Suresh G. Shenoy, Li Li, Vladimir Y. Gusev, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Valerie L. Gerlach, Karen Ellerman, John R. MacDougall, David J. Stone, Glennda Smithson
  • Publication number: 20040043926
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 26, 2001
    Publication date: March 4, 2004
    Inventors: Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, David Stone, Erik Gunther, Karen Ellerman, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Martin D. Leach, Richard A. Shimkets
  • Publication number: 20040029216
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 9, 2002
    Publication date: February 12, 2004
    Inventors: Muralidhara Padigaru, Li Li, Bryan D. Zerhusen, Stacie J. Casman, Suresh G. Shenoy, Kimberly Spytek, Mei Zhong, Esha A. Gangolli, Catherine E. Burgess, Meera Patturajan, Corine A.M. Vernet, Sarah Taylor, Velizar T. Tchernev, Charles E. Miller, Xiaojia Guo, Ferenc L. Boldog, William M. Grosse, John P. Alsobrook, Valerie L. Gerlach, Shlomit R. Edinger, Mark E. Rothenberg, Karen Ellerman, John MacDougall, Uriel M. Malyankar, Isabelle Millet, John Peyman, Glennda Smithson, Erik Gunther, David Stone
  • Publication number: 20040024181
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 26, 2001
    Publication date: February 5, 2004
    Inventors: Esha A. Gangolli, Kimberly A. Spytek, Jennifer Gilbert, Stacie Casman, Angela Blalock, Li Li, Corine Vernet, Suresh Shenoy, Vishnu S. Mishra, Katarzyna Furtak, Valerie L. Gerlach, Shlomit Edinger, Uriel Malyanker, David Stone, Isabelle Millet, Glennda Smithson, Erik Gunther, Karen Ellerman, Muralidhara Padigaru, Raymond J. Taupier, David W. Anderson
  • Publication number: 20040010118
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: August 15, 2001
    Publication date: January 15, 2004
    Inventors: Bryan D. Zerhusen, Muralidhara Padigaru, Kimberly Spytek, Steven Spaderna, Esha A. Gangolli, Luca Rastelli, Catherine E. Burgess, Kumud Majumder, Richard Shimkets, Vishnu Mishra, Corine Vernet, Edward S. Szekeres, William M. Grosse, John P. Alsobrook, Xiaohong Liu, Valerie L. Gerlach, Karen Ellerman, Glennda Smithson, John Peyman, David Stone, John MacDougall
  • Publication number: 20030212255
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and TRA 1536859v1 antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 25, 2001
    Publication date: November 13, 2003
    Inventors: Muralidhara Padigaru, Peter Mezes, Vishnu Mishra, Catherine Burgess, Stacie Casman, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Valerie L. Gerlach, John R. MacDougall, Glennda Smithson
  • Publication number: 20030211485
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: May 29, 2002
    Publication date: November 13, 2003
    Inventors: Valerie L. Gerlach, John R. MacDougall, David J. Stone, Glennda Smithson, Muralidhara Padigaru, Catherine Burgess, Corine Vernet, Elma Fernandes, Richard A. Shimkets, Velizar T. Tchernev, Vishnu Mishra, Stacie Casman, Kimberly A. Spytek, Bryan Zerhusen
  • Publication number: 20030170838
    Abstract: Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatability complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 17, 2001
    Publication date: September 11, 2003
    Inventors: Vishnu S. Mishra, Kimberly Ann Spytek, Raymond J. Taupier, Corine A. Vernet, Steven D. Colman, Linda Gorman, Velizar T. Tchernev, Uriel M. Malyankar, Suresh Shenoy, Muralidhara Padigaru, Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, John Peyman, David Stone, Erik Gunther, Karen Ellerman, Li Li, Luca Rastelli, Bryan Zerhusen
  • Publication number: 20030165858
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 18, 2001
    Publication date: September 4, 2003
    Inventors: Muralidhara Padigaru, Valerie L. Gerlach, Glennda Smithson, David Stone, Ruey Bing-Yang, Pamela B. Conley, Matthew Hart, James E. Tomlinson, James Newman Topper, Ramesh Kekuda, Stacie J. Casman, John R. MacDougall, Shlomit R. Edinger
  • Publication number: 20030149237
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: June 27, 2001
    Publication date: August 7, 2003
    Inventors: Corine Vernet, Velizar Tchernev, Meera Patturajan, Uriel M. Malyankar, Vladimir Gusev, John L. Herrmann, John R. MacDougall, Luca Rastelli, Haihong Zhong, Kimberly A. Spytek, Suresh Shenoy, Valerie L. Gerlach, Esha A. Gangolli, David J. Stone, Glennda Smithson
  • Publication number: 20030077794
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: July 3, 2001
    Publication date: April 24, 2003
    Inventors: Valerie L. Gerlach, John R. MacDougall, Glennda Smithson
  • Publication number: 20030077774
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: October 3, 2001
    Publication date: April 24, 2003
    Inventors: Valerie L. Gerlach, Karen Ellerman, John MacDougall, Glennda Smithson, Richard A. Shimkets, Luca Rastelli, John Herrmann
  • Publication number: 20030077697
    Abstract: The present invention provides a novel isolated SER5 polynucleotide and a polypeptide encoded by the SER5 polynucleotide. Also provided are the antibodies that immunospecifically bind to a SER5 polypeptide or any derivative, variant, mutant or fragment of the SER5 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SER5 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states as well as other uses.
    Type: Application
    Filed: July 3, 2001
    Publication date: April 24, 2003
    Inventors: Valerie L. Gerlach, John R. MacDougall, Kerry E. Quinn, Kumud Majumder, Kimberly A. Spytek, Corine Vernet, Catherine E. Burgess, Elma R. Fernandes, Luca Rastelli, John L. Herrmann, Steven K. Spaderna, Richard A. Shimkets, Raymond J. Taupier
  • Publication number: 20030068618
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 25, 2001
    Publication date: April 10, 2003
    Inventors: Muralidharu Padigaru, Stacie J. Casman, Catherine E. Burgess, Valerie L. Gerlach, John R. MacDougall, Glennda Smithson
  • Publication number: 20030064369
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 30, 2001
    Publication date: April 3, 2003
    Inventors: Raymond J. Taupier, Muralidhara Padigaru, Luca Rastelli, Steven Kurt Spaderna, Richard A. Shimkets, Bryan D. Zerhusen, Kimberly Ann Spytek, Suresh G. Shenoy, Li Li, Vladimir Y. Gusev, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Valerie L. Gerlach, Karen Ellerman, John R. MacDougall, David J. Stone, Glennda Smithson
  • Publication number: 20030059775
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 5, 2001
    Publication date: March 27, 2003
    Inventors: Muralidhara Padigaru, Esha A. Gangolli, Suresh Shenoy, Valerie L. Gerlach, John MacDougall, Glennda Smithson, David Stone, Karen Ellerman
  • Publication number: 20020123612
    Abstract: The invention provides polypeptides, designated herein as POLYX polypeptides, as well as polynucleotides encoding POLYX polypeptides, and antibodies that immunospecifically-bind to POLYX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the POLYX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.
    Type: Application
    Filed: July 3, 2001
    Publication date: September 5, 2002
    Inventors: Valerie L. Gerlach, Karen Ellerman, John R. MacDougall, Glennda Smithson