Abstract: A non-reusable syringe. The syringe comprises a cylinder having a plunger, with the cylinder being adapted to receive a needle. The plunger has a piston rod with a piston at one end thereof and a handle at the opposed end, with the piston being within the cylinder and the handle extending from the cylinder. The piston is movable within the cylinder to permit filling of the cylinder with liquid. The cylinder has a section of reduced diameter in sliding engagement with the piston rod, the section of reduced diameter preventing removal of the piston from the cylinder. The piston has at least one orifice therethrough filled with a non-toxic substance that is dissolvable in the liquid.