Patents by Inventor Valerie Niddam-Hildesheim

Valerie Niddam-Hildesheim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nilotinib HCl crystalline forms
    Patent number: 8592442
    Abstract: Crystalline forms of Nilotinib HCl are described.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: November 26, 2013
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Greta Sterimbaum, Sigalit Levi, Adi Yeori, Tamas Koltai, Valerie Niddam-Hildesheim, Maytal Piran, Shay Asis, Hagit Eisen-Nevo, David Malcolm Crowe
  • NILOTINIB HCL CRYSTALLINE FORMS
    Publication number: 20130096304
    Abstract: Crystalline forms of Nilotinib HCl are described.
    Type: Application
    Filed: June 27, 2012
    Publication date: April 18, 2013
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD.
    Inventors: Greta Sterimbaum, Sigalit Levi, Adi Yeori, Tamas Koltai, Valerie Niddam-Hildesheim, Maytal Piran, Shay Asis, Hagit Eisen-Nevo, David Malcolm Crowe
  • Nilotinib HCl crystalline forms
    Patent number: 8227477
    Abstract: Crystalline forms of Nilotinib HCl are described.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: July 24, 2012
    Inventors: Greta Sterimbaum, Sigalit Levi, Adi Yeori, Tamas Koltai, Valerie Niddam-Hildesheim, Maytal Piran, Shay Asis, Hagit Eisen-Nevo, David Malcolm Crowe
  • Crystal forms of O-desmethylvenlafaxine fumarate
    Patent number: 8063250
    Abstract: Provided are crystalline forms of O-desmethylvenlafaxine fumarate, methods for their preparation, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: November 22, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Valerie Niddam-Hildesheim, Eli Lancry, Sharona Shachan-tov, Sigalit Levi, Tamar Nidam
  • Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof
    Patent number: 8063211
    Abstract: The present invention provides rosuvastatin and intermediates thereof having a low level of alkylether impurity and processes for the preparation thereof.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: November 22, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Valerie Niddam-Hildesheim, Anna Balanov, Natalia Shenkar
  • Crystalline rosuvastatin calcium and compositions thereof for treatment of hyperlipidaemia
    Patent number: 7994178
    Abstract: The present invention provides a crystalline form of rosuvastatin calcium characterized by an X-ray powder diffraction pattern having peaks at about 4.7, 19.4 and 22.3° 2?±0.2° 2?. The crystalline form of the invention may be further characterized by a DSC thermogram with an endotherm at about 132° C. and another broad endotherm at about 220° C. to about 240° C., and a TGA thermogram showing a weight loss of about of 3 to about 5 percent up to about 100° C. The invention also provides a pharmaceutical composition comprising the crystalline rosuvastatin calcium, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: August 9, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Shlomit Wizel, Valerie Niddam-Hildesheim, Shalom Shabat
  • SOLID STATES OF O-DESMETHYLVENLAFAXINE SALTS
    Publication number: 20110112200
    Abstract: The present invention provides crystalline and amorphous salts of O-desmethylvenlafaxine and processes for preparing said salts of O-desmethylvenlafaxine. The present invention further provides pharmaceutical compositions comprising said salts of O-desmethylvenlafaxine.
    Type: Application
    Filed: June 16, 2009
    Publication date: May 12, 2011
    Inventors: Valerie Niddam-Hildesheim, Tamar Nidam, Eli Lancry
  • Purification of rosuvatatin intermediate by thin film evaporation and chemical method
    Patent number: 7884226
    Abstract: Provided are processes for the purification of a pure rosuvastatin intermediate by thin film evaporation and chemical method, and conversion of the intermediate to rosuvastatin or salts thereof.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: February 8, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Tamar Nidam, Omer Malachi, Irena Veinberg, Valerie Niddam-Hildesheim, Vinod Kumar Kansal, Harish Ranjan, Appu Ekambaram Ponnuswamy, Sunil Rokad, Surat Kiran, Debashish Das
  • Crystalline rosuvastatin intermediate
    Patent number: 7868169
    Abstract: Provided is a crystalline rosuvastatin intermediate and processes for preparation thereof.
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: January 11, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Valerie Niddam-Hildesheim, Natalia Shenkar, Shlomit Wizel
  • Triol form of rosuvastatin and synthesis of rosuvastatin
    Patent number: 7851624
    Abstract: Provided is a rosuvastatin triol and its use as a reference standard for analysis of rosuvastatin. Also provided are methods for preparation of rosuvastatin.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: December 14, 2010
    Assignee: Teva Pharamaceutical Industries Ltd.
    Inventors: Valerie Niddam-Hildesheim, Anna Balanov, Irena Veinberg
  • Crystalline ammonium salts of rosuvastatin
    Patent number: 7777034
    Abstract: Provided are alkyl ammonium crystalline salts of rosuvastatin that provide for purification of rosuvastatin and its pharmaceutically acceptable salts.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: August 17, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Valerie Niddam-Hildesheim, Judith Aronhime, Kobi Chen
  • DIASTEREOMERIC PURIFICATION OF ROSUVASTATIN
    Publication number: 20100197916
    Abstract: The invention relates to diastereomerically pure rosuvastatin and processes for preparing diastereomerically pure rosuvastatin and its intermediates.
    Type: Application
    Filed: February 2, 2010
    Publication date: August 5, 2010
    Inventors: Valerie NIDDAM-HILDESHEIM, Natalia SHENKAR, Kobi CHEN, Anna BALANOV
  • NILOTINIB HCL CRYSTALLINE FORMS
    Publication number: 20100190812
    Abstract: Crystalline forms of Nilotinib HCl are described.
    Type: Application
    Filed: November 5, 2009
    Publication date: July 29, 2010
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Greta STERIMBAUM, Sigalit LEVI, Adi YEORI, Tamas KOLTAI, Valerie NIDDAM-HILDESHEIM, Maytal PIRAN, Shay ASIS, Hagit Eisen-Nevo, David Malcolm CROWE
  • Crystal forms of O-desmethylvenlafaxine
    Patent number: 7674935
    Abstract: Methods for preparing crystalline forms of O-desmethylvenlafaxine are described.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: March 9, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Sigalit Levi, Valerie Niddam-Hildesheim, Iamas Koltai
  • Process for the preparation of rosuvstatin
    Patent number: 7655796
    Abstract: The present invention provides a process for the preparation of the rosuvastatin intermediate FPP-CHO and its conversion to rosuvastatin and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: February 2, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Valerie Niddam-Hildesheim, Kobi Chen
  • GABAPENTIN ENACARBIL SALTS AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20100004485
    Abstract: The preparation and use of calcium, barium, magnesium and copper salts of gabapentin enacarbil are described.
    Type: Application
    Filed: July 2, 2009
    Publication date: January 7, 2010
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD.
    Inventors: Meital COHEN, Valerie NIDDAM-HILDESHEIM, Maytal PIRAN, Elena BEN MOHA-LERMAN
  • PROCESSES FOR PREPARING PRODRUGS OF GABAPENTIN AND INTERMEDIATES THEREOF
    Publication number: 20090318728
    Abstract: Gabapentin prodrugs and intermediates thereof are described.
    Type: Application
    Filed: June 24, 2009
    Publication date: December 24, 2009
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD.
    Inventors: Elena Ben Moha-Lerman, Valerie Niddam-Hildesheim
  • Preparation of levofloxacin and hemihydrate thereof
    Patent number: 7629458
    Abstract: The invention provides a method for preparing levofloxacin hemihydrate, comprising: maintaining levofloxacin at a first elevated temperature in a first solvent; adding a polar solvent to precipitate the levofloxacin hemihydrate, wherein the polar solvent comprises water; and recovering the levofloxacin hemihydrate. The invention also provides a method of converting a levofloxacin form to levofloxacin hemihydrate, comprising storing one or more forms selected from the group consisting of Forms A, B, C, F, G and H for a sufficient time to permit the one or more forms to convert to levofloxacin hemihydrate.
    Type: Grant
    Filed: October 3, 2002
    Date of Patent: December 8, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Valerie Niddam-Hildesheim, Neomi Gershon, Ehud Amir, Shlomit Wizel
  • Substantially pure O-desmethylvenlafaxine and processes for preparing it
    Publication number: 20090292142
    Abstract: Methods for preparing substantially pure O-desmethylvenlafaxine are described.
    Type: Application
    Filed: August 3, 2009
    Publication date: November 26, 2009
    Inventor: Valerie Niddam-Hildesheim
  • Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof
    Patent number: 7612203
    Abstract: The present invention provides rosuvastatin and intermediates thereof having a low level of alkylether impurity and processes for the preparation thereof.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: November 3, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Valerie Niddam-Hildesheim, Anna Balanov, Natalia Shenkar