Patents by Inventor Valerie Perrine Calabro

Valerie Perrine Calabro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ankyrin repeat binding proteins and their uses
    Patent number: 11466062
    Abstract: The present invention relates to recombinant binding proteins comprising one or more designed ankyrin repeat domains with binding specificity for coronavirus spike proteins, nucleic acids encoding such proteins, pharmaceutical compositions comprising such proteins or nucleic acids, and the use of such proteins, nucleic acids or pharmaceutical compositions in the treatment of coronavirus diseases, particularly diseases caused by SARS-CoV-2.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: October 11, 2022
    Assignee: MOLECULAR PARTNERS AG
    Inventors: Patrick Amstutz, Valerie Perrine Calabro, Marcel Walser
  • NOVEL ANKYRIN REPEAT BINDING PROTEINS AND THEIR USES
    Publication number: 20220235103
    Abstract: The present invention relates to recombinant binding proteins comprising one or more designed ankyrin repeat domains with binding specificity for coronavirus spike proteins, nucleic acids encoding such proteins, pharmaceutical compositions comprising such proteins or nucleic acids, and the use of such proteins, nucleic acids or pharmaceutical compositions in the treatment of coronavirus diseases, particularly diseases caused by SARS-CoV-2.
    Type: Application
    Filed: February 11, 2022
    Publication date: July 28, 2022
    Inventors: Patrick AMSTUTZ, Valerie Perrine CALABRO, Marcel WALSER
  • MULTISPECIFIC PROTEINS
    Publication number: 20210395318
    Abstract: The present disclosure relates to multispecific proteins comprising designed ankyrin repeat domains with binding specificity for different targets, such as, e.g. CD40 and FAP. In addition, the present disclosure relates to nucleic acids encoding such multispecific proteins, pharmaceutical compositions comprising such multispecific proteins or nucleic acids, and the use of such binding proteins, nucleic acids or pharmaceutical compositions in methods for treating or diagnosing diseases, such as cancer, in a mammal, including a human.
    Type: Application
    Filed: May 14, 2021
    Publication date: December 23, 2021
    Inventors: Nicolo RIGAMONTI, Clara DOMKE, Valérie Perrine CALABRO, Pamela Anna TRAIL SMITH, Victor LEVITSKY, Niina Elisabet VEITONMÄKI
  • NOVEL ANKYRIN REPEAT BINDING PROTEINS AND THEIR USES
    Publication number: 20210347835
    Abstract: The present invention relates to recombinant binding proteins comprising one or more designed ankyrin repeat domains with binding specificity for coronavirus spike proteins, nucleic acids encoding such proteins, pharmaceutical compositions comprising such proteins or nucleic acids, and the use of such proteins, nucleic acids or pharmaceutical compositions in the treatment of coronavirus diseases, particularly diseases caused by SARS-CoV-2.
    Type: Application
    Filed: May 6, 2021
    Publication date: November 11, 2021
    Inventors: Patrick AMSTUTZ, Valerie Perrine CALABRO, Marcel WALSER
  • Designer osteogenic proteins
    Patent number: 11008373
    Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: May 18, 2021
    Assignee: Wyeth, LLC.
    Inventors: Stephen Berasi, Robert Vincent Martinez, Michael John Cain, John Martin Wozney, Howard Seeherman, Zong Sean Juo, Valerie Perrine Calabro, Christopher Todd Brown
  • DESIGNER OSTEOGENIC PROTEINS
    Publication number: 20190241634
    Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
    Type: Application
    Filed: December 6, 2018
    Publication date: August 8, 2019
    Inventors: Stephen BERASI, Robert Vincent Martinez, Michael John Cain, John Martin Wozney, Howard Joel Seeherman, Zong Sean Juo, Valerie Perrine Calabro, Christopher Todd Brown
  • Osteogenic proteins
    Patent number: 10196433
    Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: February 5, 2019
    Assignee: Wyeth LLC
    Inventors: Stephen Berasi, Robert Vincent Martinez, Michael John Cain, John Martin Wozney, Howard Joel Seeherman, Zong Sean Juo, Valerie Perrine Calabro, Christopher Todd Brown
  • OSTEOGENIC PROTEINS
    Publication number: 20180134762
    Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
    Type: Application
    Filed: May 5, 2017
    Publication date: May 17, 2018
    Inventors: Stephen BERASI, Robert Vincent Martinez, Michael John Cain, John Martin Wozney, Howard Joel Seeherman, Zong Sean Juo, Valerie Perrine Calabro, Christopher Todd Brown
  • Designer osteogenic proteins
    Patent number: 9688735
    Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: June 27, 2017
    Assignee: Wyeth LLC
    Inventors: Stephen Berasi, Robert Vincent Martinez, Michael John Cain, John Martin Wozney, Howard Joel Seeherman, Zong Sean Juo, Valerie Perrine Calabro, Christopher Todd Brown
  • DESIGNER OSTEOGENIC PROTEINS
    Publication number: 20160207973
    Abstract: The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
    Type: Application
    Filed: January 5, 2015
    Publication date: July 21, 2016
    Inventors: Stephen BERASI, Robert Vincent Martinez, Michael John Cain, John Martin Wozney, Howard Joel Seeherman, Zong Sean Juo, Valerie Perrine Calabro, Christopher Todd Brown