Patents by Inventor Valerie S. Bernan

Valerie S. Bernan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for Producing Anticancer Agent LL-D45042
    Publication number: 20100022593
    Abstract: The disclosure describes the production of anticancer agent LL-D45042, having the structure: by fermentation, to methods for the recovery and concentration of this anticancer agent from crude solutions, and to processes for the purification of this anticancer agent as well as a new microorganism of the species Streptomyces hygroscopicus LL-D45042 and mutants thereof useful in the preparation of this compound.
    Type: Application
    Filed: September 29, 2009
    Publication date: January 28, 2010
    Applicant: Wyeth Holdings Corporation
    Inventors: Valerie S. Bernan, Edmund I. Graziani
  • Antibiotic P175-A and semisynthetic derivatives thereof
    Patent number: 7211417
    Abstract: This invention relates to a new antibiotic designated P175-A, to production of fermentation of Micromonospora echinospora NRRL 30633, to methods for recovery and concentration from the crude solutions, and to a process for purification and to semisynthetic esters and ethers of P175-A.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: May 1, 2007
    Assignee: Wyeth Holdings Corporation
    Inventors: Haiyin He, Hui Yu Yang, Scott William Luckman, Valerie S. Bernan
  • Process for producing anticancer agent LL-D45042
    Patent number: 7019014
    Abstract: The disclosure describes the production of anticancer agent LL-D45042, having the structure: by fermentation, to methods for the recovery and concentration of this anticancer agent from crude solutions, and to processes for the purification of this anticancer agent as well as a new microorganism of the species Streptomyces hygroscopicus LL-D45042 and mutants thereof useful in the preparation of this compound.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: March 28, 2006
    Assignee: Wyeth Holdings Corporation
    Inventors: Valerie S. Bernan, Edmund I. Graziani
  • Process for producing anticancer agent LL-D45042
    Publication number: 20040229323
    Abstract: The disclosure describes the production of anticancer agent LL-D45042, having the structure: 1
    Type: Application
    Filed: May 10, 2004
    Publication date: November 18, 2004
    Applicant: Wyeth Holdings Corporation
    Inventors: Valerie S. Bernan, Edmund I. Graziani
  • Antibiotic P175-A and semisynthetic derivatives thereof
    Publication number: 20040220195
    Abstract: This invention relates to a new antibiotic designated P175-A, to production of fermentation of Micromonospora echinospora NRRL 30633, to methods for recovery and concentration from the crude solutions, and to a process for purification and to semisynthetic esters and ethers of P175-A.
    Type: Application
    Filed: April 28, 2004
    Publication date: November 4, 2004
    Applicant: Wyeth Holdings Corporation
    Inventors: Haiyin He, Hui Yu Yang, Scott William Luckman, Valerie S. Bernan