Patents by Inventor Valerio Chiroli

Valerio Chiroli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology
    Patent number: 9012435
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: April 21, 2015
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Annalisa Bonfanti, Valerio Chiroli, Rebecca Steele, Ennio Ongini, Stefano Biondi
  • GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY
    Publication number: 20130303499
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Application
    Filed: July 19, 2013
    Publication date: November 14, 2013
    Inventors: Francesca BENEDINI, Annalisa BONFANTI, Valerio CHIROLI, Rebecca STEELE, Ennio ONGINI, Stefano BIONDI
  • Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology
    Patent number: 8518920
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: August 27, 2013
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Annalisa Bonfanti, Valerio Chiroli, Rebecca Steele, Ennio Ongini, Stefano Biondi
  • Nitric oxide donating prostamides
    Patent number: 8101658
    Abstract: Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: January 24, 2012
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Stefano Biondi, Valerio Chiroli, Wesley Kwan Mung Chong, Liming Dong, Achim Hans-Peter Krauss, Fabio Nicoli, Ganesh Prasanna, William Francois Vernier, Yi Yang
  • Prostaglandin derivatives
    Patent number: 8058467
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: November 15, 2011
    Assignee: Nicox S.A.
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY
    Publication number: 20110144073
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Application
    Filed: July 7, 2009
    Publication date: June 16, 2011
    Inventors: Francesca Benedini, Annalisa Bonfanti, Valerio Chiroli, Rebecca Steele, Ennio Ongini, Stefano Biondi
  • PROSTAGLANDIN DERIVATIVES
    Publication number: 20110136904
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: February 11, 2011
    Publication date: June 9, 2011
    Applicant: NICOX S.A.
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • NEW NO-RELEASING STEROIDS FOR THE TREATMENT OF RETINA AND MACULA LUTEA DISEASES
    Publication number: 20110130375
    Abstract: The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof The compounds are useful for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Application
    Filed: July 24, 2009
    Publication date: June 2, 2011
    Applicant: NICOX S.A.
    Inventors: Francesca Benedini, Rebecca Steele, Valerio Chiroli, Stefano Biondi, Ennio Ongini
  • NITRIC OXIDE DONATING PROSTAMIDES
    Publication number: 20110092590
    Abstract: Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: May 11, 2009
    Publication date: April 21, 2011
    Applicant: NICOX S.A.
    Inventors: Francesca Benedini, Stefano Biondi, Valerio Chiroli, Wesley Kwan Mung Chong, Liming Dong, Achim Hans-Peter Krauss, Fabio Nicoli, Ganesh Prasanna, William Francois Vernier, Yi Yang
  • Prostaglandin derivatives
    Patent number: 7910767
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: March 22, 2011
    Assignee: Nicox S.A.
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • PROSTAGLANDIN DERIVATIVES
    Publication number: 20100130507
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 27, 2010
    Applicant: NICOX S.A.
    Inventors: Ennio ONGINI, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • Prostaglandin derivatives
    Patent number: 7718656
    Abstract: Nitroderivatives of prostaglandin amides having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: May 18, 2010
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Valerio Chiroli, Wesley Kwan Mung Chong, Achim Hans-Peter Krauss, Michael Ross Niesman, Ennio Ongini
  • Prostaglandin derivatives
    Patent number: 7629345
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: December 8, 2009
    Assignee: Nicox S.A.
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • Prostaglandin derivatives
    Publication number: 20090062296
    Abstract: Nitroderivatives of prostaglandin amides having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: June 28, 2006
    Publication date: March 5, 2009
    Inventors: Francesca Benedini, Valerio Chiroli, Wesley Kwan Mung Chong, Achim Hans-Peter Krauss, Michael Ross Niesman, Ennio Ongini
  • PROSTAGLANDIN DERIVATIVES
    Publication number: 20090030076
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: September 15, 2008
    Publication date: January 29, 2009
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • Prostaglandin derivatives
    Patent number: 7449469
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: November 11, 2008
    Assignee: Nicox S.A.
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • PROSTAGLANDIN DERIVATIVES
    Publication number: 20080058392
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: August 20, 2007
    Publication date: March 6, 2008
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • Prostaglandin derivatives
    Patent number: 7273946
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: September 25, 2007
    Assignee: Nicox S.A.
    Inventors: Eninnio Ongini, Valerio Chiroli, Francesca Benedini, Piero Del Soldato
  • Prostaglandin derivatives
    Publication number: 20050272743
    Abstract: Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: January 5, 2005
    Publication date: December 8, 2005
    Applicant: NicOx S.A.
    Inventors: Ennio Ongini, Valerio Chiroli, Francesca Benedini, Piero Soldato