Patents by Inventor Valery Vladimirovich SOLOVYEV

Valery Vladimirovich SOLOVYEV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody or an antigen-binding fragment thereof capable of binding to a human receptor of interleukin-6
    Patent number: 11993647
    Abstract: The invention relates to medicine. The problem addressed by the present invention consists in creating alternative antibodies or fragments thereof which are capable of specifically binding to a human receptor of interleukin-6 and which would be useful as drugs for treating or diagnosing diseases, or for relieving symptoms, mediated by interleukin-6.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: May 28, 2024
    Inventors: Stanislav Rudolfovich Evdokimov, Andrei Borisovich Ulitin, Valery Vladimirovich Solovyev, Aleksei Aleksandrovich Aleksandrov, Yulia Sergeevna Chernykh, Timofey Aleksandrovich Nemankin, Anna Konstantinovna Vladimirova, Oleg Igorevich Smotrov, Tatiana Veniaminovna Chernovskaya, Aleksandr Aleksandrovich Moshchenko, Viktoriia Evgenevna Nalobina, Roman Alekseevich Ivanov, Dmitry Valentinovich Morozov
  • IMMUNOCYTOKINE FOR ACTIVATING HUMAN IL-10RA RECEPTOR AND USE THEREOF
    Publication number: 20240034764
    Abstract: The present invention relates to the field of biotechnology and medicine, in particular to an immunocytokine for activating the human IL-10R? receptor. The invention further relates to nucleic acids encoding said immunocytokine, expression vectors, host cells and methods for producing same, methods for producing the immunocytokine, pharmaceutical compositions comprising the above immunocytokine, pharmaceutical compositions comprising the above immunocytokine and other therapeutically active compounds, methods for treating an oncological disease and the uses of the immunocytokine or pharmaceutical compositions thereof for treating an oncological disease.
    Type: Application
    Filed: December 10, 2021
    Publication date: February 1, 2024
    Inventors: Aleksey Vladimirovich KONONOV, Iuliia Viktorovna EVDOKIMOVSKAIA, Iana Andreevna SMIRNOVA, Stanislav Rudolfovich EVDOKIMOV, Elena Sergeevna KOLOSOVA, Sergei Andreevich AGEEV, Vladimir Sergeevich TSYMPILOV, Valery Vladimirovich SOLOVYEV, Pavel Andreevich IAKOVLEV, Dmitry Valentinovich MOROZOV
  • Bispecific antibodies with specific binding to CD47 and PD-L1
    Patent number: 11840567
    Abstract: The present invention relates to the field of bioengineering, specifically to antibodies or their antigen-binding fragments, and to the use thereof. More particularly, the present invention relates to antibodies that bind specifically to CD47 and PD-L1. The invention also relates to a nucleic acid that codes for the given antibody or for the antigen-binding fragment thereof, to an expression vector, to a method of producing the antibody, and to a use of the aforementioned antibodies and compositions in cancer treatment.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: December 12, 2023
    Inventors: Kirill Vladimirovich Solovyev, Andrei Borisovich Ulitin, Timofey Aleksandrovich Nemankin, Valery Vladimirovich Solovyev, Dmitry Valentinovich Morozov
  • MONOCLONAL ANTIBODY THAT BINDS SPECIFICALLY TO GITR
    Publication number: 20220213209
    Abstract: The present invention relates to biotechnology, in particular to antibodies or antigen-binding fragments thereof, and to use thereof. More particularly, the present invention relates to monoclonal antibodies that specifically bind to GITR. The invention also relates to a nucleic acid encoding said antibody or antigen-binding fragment thereof, an expression vector, a method for preparing said antibody, and use of said antibody in treatment of diseases or disorders associated with GITR.
    Type: Application
    Filed: April 23, 2020
    Publication date: July 7, 2022
    Inventors: Andrei Borisovich ULITIN, Olesya Nikolaevna KOZLOVA, Aleksandr Andreevich GORDEEV, Ksenia Mihailovna BURNYSHEVA, Anastasia Nikolaevna ISHUTINOVA, Aleksandra Aleksandrovna SOZONOVA, Sergei Andreevich AGEEV, Aleksandr Nikolaevich DORONIN, Vladimir Sergeevich TSYMPILOV, Ivan Vladimirovich MITROSHIN, Valery Vladimirovich SOLOVYEV, Iakov Iurevich USTIUGOV, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV
  • MONOCLONAL ANTIBODY THAT SPECIFICALLY BINDS TO CD20
    Publication number: 20220089761
    Abstract: The present invention relates to biotechnology and provides a monoclonal antibody that specifically binds to CD20. The invention also relates to DNA encoding said antibody, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibody.
    Type: Application
    Filed: October 30, 2019
    Publication date: March 24, 2022
    Inventors: Pavel Andreevich IAKOVLEV, Natalia Eugenievna PESTOVA, Arina Vitalevna ANIKINA, Anna Alexandrovna TRUDOVISHNIKOVA, Mariia Aleksandrovna SHCHEMELEVA, Nina Grachyaevna KHARATIAN, Valery Vladimirovich SOLOVYEV, Alexey Konstantinovich MISORIN, Sergei Vasilyevich DIDUK, Anna Vladimirovna EROSHOVA, Veronika Sergeevna USATOVA, Elena Andreevna KRENDELEVA, Iakov Iurevich USTIUGOV, Aleksei Aleksandrovich ALEKSANDROV, Iana Andreevna SMIRNOVA, Svetlana Vladimirovna KOSKOVA, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV
  • Monoclonal antibody to PD-L1
    Patent number: 11236167
    Abstract: The present invention relates to the field of biotechnology and provides antibodies that specifically binds to PD-L1. The invention also relates to DNA encoding said antibodies, to corresponding expression vectors and to methods of producing, and to methods of treatment using said antibodies.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: February 1, 2022
    Inventors: Andrei Borisovich Ulitin, Viktoriia Mikhailovna Ekimova, Ekaterina Vladimirovna Sofronova, Yulia Sergeevna Chernykh, Sergei Andreevich Ageev, Anna Konstantinovna Vladimirova, Aleksei Aleksandrovich Aleksandrov, Pavel Alekseevich Grebnev, Valery Vladimirovich Solovyev, Iakov Iurevich Ustiugov, Pavel Andreevich Iakovlev, Timofey Aleksandrovich Nemankin, Dmitry Valentinovich Morozov
  • Anti-PD-1 antibodies, method for producing same and method for using same
    Patent number: 11136408
    Abstract: The present invention relates to biotechnology and comprises isolated monoclonal antibodies, in particular human monoclonal antibodies, which specifically bind to PD-1 with high affinity. The antibodies according to the invention may be chimeric, humanized or human antibodies, or antigen-binding fragments thereof, and may be used as a medicinal agent in oncology and immuno-oncology, for treating diseases associated with various cell proliferation or development disorders. The invention also relates to methods for producing said antibodies and a method for treating human diseases using said antibodies.
    Type: Grant
    Filed: July 4, 2017
    Date of Patent: October 5, 2021
    Inventors: Viktoriia Mikhailovna Ekimova, Dmitry Valeryevich Korzhavin, Yulia Sergeevna Chernykh, Timofey Aleksandrovich Nemankin, Valery Vladimirovich Solovyev, Anna Konstantinovna Vladimirova, Irina Andreevna Bulankina, Sergei Vasilyevich Diduk, Olga Vladimirovna Goncharova, Anna Vladimirovna Eroshova, Iakov Lurevich Ustiugov, Marina Vladimirovna Artiukhova, Andrei Borisovich Ulitin, Roman Alekseevich Ivanov, Dmitry Valentinovich Morozov
  • MONOCLONAL ANTIBODY TO PD-L1
    Publication number: 20200369771
    Abstract: The present invention relates to the field of biotechnology and provides antibodies that specifically binds to PD-L1. The invention also relates to DNA encoding said antibodies, to corresponding expression vectors and to methods of producing, and to methods of treatment using said antibodies.
    Type: Application
    Filed: April 11, 2018
    Publication date: November 26, 2020
    Inventors: Andrey Borisovich ULITIN, Victoria Mikhailovna EKIMOVA, Ekaterina Vladimirovna SOFRONOVA,, Yulia Sergeevna CHERNYKH, Sergei Andreevich AGEEV, Anna Konstantinovna VLADIMIROVA, Aleksei Aleksandrovich ALEKSANDROV, Pavel Alekseevich GREBNEV, Valery Vladimirovich SOLOVYEV, Iakov Iurevich USTIUGOV, Pavel Andreevich IAKOVLEV, Timofey Aleksandrovich NEMANKIN, Dmitry Valentinovich MOROZOV
  • ANTI-IL-5RAlpha MONOCLONAL ANTIBODY
    Publication number: 20200291121
    Abstract: The present invention relates to biotechnology and provides antibodies that specifically bind to IL-5R?. The invention also relates to DNA encoding said antibodies, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibodies.
    Type: Application
    Filed: October 2, 2018
    Publication date: September 17, 2020
    Inventors: Ekaterina Vladimirovna SOFRONOVA, Aleksei Konstantinovich MISORIN, Aleksandr Nikolaevich DORONIN, Timofey Aleksandrovich NEMANKIN, Aleksandra Aleksandrovna SOZONOVA, Galina Stepanovna ZHIRIVSKAIA, Sergey Aleksandrovich LEGOTSKY, Anna Konstantinovna VLADIMIROVA, Alina Valerevna BELIASNIKOVA, Mariia Aleksandrovna SHCHEMELEVA, Pavel Andreevich IAKOVLEV, Valery Vladimirovich SOLOVYEV, Elena Andreevna KRENDELEVA, Natalia Evgenevna PESTOVA, Dmitry Valentinovich MOROZOV
  • Antibodies specific to CD47 and PD-L1
    Publication number: 20200270345
    Abstract: The present invention relates to the field of bioengineering, specifically to antibodies or their antigen-binding fragments, and to the use thereof. More particularly, the present invention relates to antibodies that bind specifically to CD47 and PD-L1. The invention also relates to a nucleic acid that codes for the given antibody or for the antigen-binding fragment thereof, to an expression vector, to a method of producing the antibody, and to a use of the aforementioned antibodies and compositions in cancer treatment.
    Type: Application
    Filed: October 3, 2018
    Publication date: August 27, 2020
    Inventors: Kirill Vladimirovich SOLOVYEV, Andrei Borisovich ULITIN, Timofey Aleksandrovich NEMANKIN, Valery Vladimirovich SOLOVYEV, Dmitry Valentinovich MOROZOV
  • ANTIBODY OR AN ANTIGEN-BINDING FRAGMENT THEREOF CAPABLE OF BINDING TO A HUMAN RECEPTOR OF INTERLEUKIN-6
    Publication number: 20190194313
    Abstract: The invention relates to medicine. The problem addressed by the present invention consists in creating alternative antibodies or fragments thereof which are capable of specifically binding to a human receptor of interleukin-6 and which would be useful as drugs for treating or diagnosing diseases, or for relieving symptoms, mediated by interleukin-6.
    Type: Application
    Filed: August 3, 2017
    Publication date: June 27, 2019
    Inventors: Stanislav Rudolfovich EVDOKIMOV, Andrei Borisovich ULITIN, Valery Vladimirovich SOLOVYEV, Aleksei Aleksandrovich ALEKSANDROV, Yulia Sergeevna CHERNYKH, Timofey Aleksandrovich NEMANKIN, Anna Konstantinovna VLADIMIROVA, Oleg Igorevich SMOTROV, Tatiana Veniaminovna CHERNOVSKAYA, Aleksandr Aleksandrovich MOSHCHENKO, Viktoriia Evgenevna NALOBINA, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV
  • ANTI-PD-1 ANTIBODIES, METHOD FOR PRODUCING SAME AND METHOD FOR USING SAME
    Publication number: 20190127478
    Abstract: The present invention relates to biotechnology and comprises isolated monoclonal antibodies, in particular human monoclonal antibodies, which specifically bind to PD-1 with high affinity. The antibodies according to the invention may be chimeric, humanized or human antibodies, or antigen-binding fragments thereof, and may be used as a medicinal agent in oncology and immuno-oncology, for treating diseases associated with various cell proliferation or development disorders. The invention also relates to methods for producing said antibodies and a method for treating human diseases using said antibodies.
    Type: Application
    Filed: July 4, 2017
    Publication date: May 2, 2019
    Inventors: Viktoriia Mikhailovna EKIMOVA, Dmitry Valeryevich KORZHAVIN, Yulia Sergeevna CHERNYKH, Timofey Aleksandrovich NEMANKIN, Valery Vladimirovich SOLOVYEV, Anna Konstantinovna VLADIMIROVA, Irina Andreevna BULANKINA, Sergei Vasilyevich DIDUK, Olga Vladimirovna GONCHAROVA, Anna Vladimirovna EROSHOVA, Iakov Iurevich USTIUGOV, Marina Vladimirovna ARTIUKHOVA, Andrei Borisovich ULITIN, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV