Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measurable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measurable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measurable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: Methods of providing embolic protection during treatment of a vessel include advancing a microcatheter in the vessel, inserting a textile structure in a collapsed state into the microcatheter, and advancing the textile structure through the microcatheter. The methods may include, after advancing the textile structure and retracting the microcatheter to unsheathe a self-expanding bulb of the textile structure from the microcatheter, thereby allowing the self-expanding bulb to self-expand from the collapsed state to an expanded state. The methods may include performing a vascular procedure. In the expanded state, the self-expanding bulb may filter emboli released during performing the vascular procedure.

Abstract: Methods of forming a structure for treating a vessel include providing a mandrel and braiding a plurality of filaments around the mandrel. The mandrel may include a strand having a longitudinal axis and a plurality of balls coupled to the strand along the longitudinal axis. Pairs of the plurality of balls may be spaced along the longitudinal axis. Braiding the plurality of filaments around the mandrel may include, during braiding, forming a plurality of bulbs around the plurality of balls and forming necks between pairs of the plurality of balls. The methods may include, after braiding the plurality of filaments, heat treating (e.g., shape setting) the plurality of filaments on the mandrel. Portions of the braided plurality of filaments may be secured to the mandrel, for example using bangles, wire, and/or adhesive.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measurable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: A mandrel for manufacturing a vascular device for treating a vessel includes an elongate strand and a plurality of bulbs coupled to the elongate strand. The elongate strand may extend through each of the plurality of bulbs. The mandrel may include first and second elongate strands each including a plurality of bulbs. The first and second elongate strands may be separable at an intermediate portion coupling the first and second elongate strands. A vascular device manufactured utilizing the mandrel may be configured to treat a vessel.

Abstract: A biomedical shape-set textile structure based mechanical thrombectomy systems and methods are described. In one of the embodiments, the mechanical thrombectomy device can be customized to the length of the clot in each patient. In one of the embodiments, the mechanical thrombectomy device because of the textile structure has a very low overall profile or thickness that is less than 0.0125 inches (0.317 mm) and therefore can be deployed within microcatheters with inner lumen diameter as small as 0.014 inches (0.355 mm).

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: A device for treating a vessel may include a tubular member including a first portion, a second portion distal to the first portion, and a third portion distal to the second portion. The second portion may include a plurality of patterns each including longitudinally-spaced rows. Each of the rows may include two kerfs and two stems. The stems within each of the plurality of patterns may be offset in a circumferential direction, and the circumferential direction of at least two patterns of the plurality of patterns may be opposite. The second portion may further include an inflatable element radially outward of the tubular member.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: A method of modifying a hypotube may include cutting the hypotube with a laser cut pattern, winding the hypotube in a spiral collector, and flowing gas into the spiral collector. Flowing the gas into the spiral collector may include cooling the hypotube. Flowing the gas into the spiral collector may include flowing the gas into the spiral collector at a temperature between 20° C. and 25° C. The gas may include air or inert gas. The method may include holding the hypotube at a height using a bushing, a plurality of collets, and a hypotube clamp. The bushing and plurality of collets may be configured to inhibit sag of the hypotube to be less than 3% of the height. The method may include inhibiting forming fissures in the hypotube. The pattern may include a plurality of patterns each comprising longitudinally-spaced rows.

Abstract: A system for removal of slag during laser cutting of a hypotube by a laser cutting system may include a cooling system and a cooling fluid inlet regulator. The cooling system may be configured to be coupled to a laser nozzle of a laser cutting system. The cooling system may include a supply of gas and a gas inflow valve configured to regulate the gas that flows into the laser nozzle from the supply of gas. The cooling fluid inlet regulator may be configured to inject cooling fluid into an inner lumen of a hypotube during laser cutting by the laser cutting system at a velocity configured to facilitate removal of slag generated during the laser cutting of the hypotube. The cooling fluid inlet regulator may be configured to cool the hypotube during the laser cutting.

Abstract: A device for disrupting flow through a fistula may include a woven textile having a compressed state and an expanded state. The woven textile may include, in the expanded state, a neck, a first bulb coupled to a proximal side of the neck, and a second bulb coupled to a distal side of the neck. The neck has a first braid angle. The first bulb may have a second braid angle greater than the first braid angle. The second bulb may have a third braid angle greater than the first braid angle.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measurable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: A method of disrupting flow through a fistula may include deploying a flow disruptor across the fistula through a microcatheter at a point in vasculature proximate to the fistula. Deploying the flow disruptor may include expanding a first bulb on a first side of the fistula and expanding a second bulb on a second side of the fistula, the flow disruptor including a neck between the first bulb and the second bulb and traversing the fistula. The first bulb may have a first braid angle, the second bulb may have a second braid angle, and the neck may have a third braid angle less than the first braid angle and the second braid angle.

Abstract: Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

Abstract: An implantable device for treating a vascular cavity or vascular malformation may include a plurality of wires woven to form a textile structure expandable from a compressed state to an expanded state. The textile structure may have a longitudinal axis and may include, in the expanded state, a first longitudinal segment, a second longitudinal segment, and a lumen configured to allow perfusion of blood through the textile structure parallel to the longitudinal axis. The first longitudinal segment may include a first circumferential portion including a first braid angle and a second circumferential portion opposite the first circumferential portion and including a second braid angle greater than the first braid angle. At least one of the first longitudinal segment and the second longitudinal segment may comprise a bulb.