Patents by Inventor Vamshi Ramana PRATHAP

Vamshi Ramana PRATHAP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GRANULES CONTAINING POSACONAZOLE
    Publication number: 20240390363
    Abstract: The present invention relates to granules preferably prepared by subjecting a mixture containing posaconazole, an enteric polymer and optionally a non-enteric polymer to hot-melt extrusion, whereby the granules have a specific particle-size distribution and contain the drug in molecularly dispersed form, and a gastro-resistant, optionally film-coated tablet prepared from the granules.
    Type: Application
    Filed: October 7, 2022
    Publication date: November 28, 2024
    Inventors: Srikanth VELCHURI, Vamshi Ramana PRATHAP, Venkatasimhadri Naidu KALAMATA, Gaith ZOUBARI, Angar FITZNER, Bala Ramesha Chary RALLABANDI, Kiran Kumar MADALLAPALLI
  • GASTRO-RESISTANT HIGH-STRENGTH FORMULATION CONTAINING POSACONAZOLE
    Publication number: 20240293399
    Abstract: The present invention relates to a gastro-resistant high-strength unit dosage form comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains 300 mg posaconazole and an enteric polymer in a specific weight ratio. The unit dosage form may be a capsule or optionally film-coated tablet.
    Type: Application
    Filed: August 13, 2021
    Publication date: September 5, 2024
    Inventors: Vamshi Ramana PRATHAP, Venkatasimhadri Naidu KALAMATA, Ashwini Kumar MUPKALKER, Srikanth VELCHURI, Bala Ramesha Chary RALLABANDI, Kiran Kumar MADALLAPALLI, Hendrik SCHLEHAHN, Ansgar FITZNER
  • Pharmaceutical Mixture Comprising Amorphous Pitolisant
    Publication number: 20240226080
    Abstract: The present invention relates to a pharmaceutical mixture comprising amorphous pitolisant free base or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable excipient. The present invention also related to an oral dosage form containing the pharmaceutical mixture and a method for treating narcolepsy with or without cataplexy.
    Type: Application
    Filed: November 27, 2023
    Publication date: July 11, 2024
    Inventors: Vamshi Ramana Prathap, Claudia Meyer, Siva Ramanjaneyulu Chalamalasetti, Nico Steiert, Ruslan Staver, Abhay Ramakant Joshi, Sindhu Bogolu
  • TABLET CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20230346709
    Abstract: The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesoporous inorganic stabilizer, e.g. mesoporous silica (Syloid®).
    Type: Application
    Filed: April 25, 2023
    Publication date: November 2, 2023
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Krishna Mohan GOLLAPUDI, Bala Subramanian VELUSAMY, Srimannarayana BANDLA, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • Gastro-resistant formulation containing posaconazole
    Patent number: 11590127
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: February 28, 2023
    Assignee: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana Prathap, Venkatasimhadri Naidu Kalamata, Bala Ramesha Chary Rallabandi, Vinay Kumar Katakam, Hendrik Schlehahn
  • STABLE HOT-MELT EXTRUDATE CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20220226247
    Abstract: The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process.
    Type: Application
    Filed: April 7, 2022
    Publication date: July 21, 2022
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Rajesh Krishna Mohan GOLLAPUDI, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • GASTRO-RESISTANT FORMULATION CONTAINING POSACONAZOLE
    Publication number: 20210283130
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Application
    Filed: June 2, 2021
    Publication date: September 16, 2021
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana PRATHAP, Venkatasimhadri Naidu KALAMATA, Bala Ramesha Chary RALLABANDI, Vinay Kumar KATAKAM, Hendrik SCHLEHAHN
  • Gastro-resistant formulation containing posaconazole
    Patent number: 11058682
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: July 13, 2021
    Assignee: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana Prathap, Venkatasimhadri Naidu Kalamata, Bala Ramesha Chary Rallabandi, Vinay Kumar Katakam, Hendrik Schlehahn
  • STABLE HOT-MELT EXTRUDATE CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20210085610
    Abstract: The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process.
    Type: Application
    Filed: March 29, 2018
    Publication date: March 25, 2021
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Rajesh Krishna Mohan GOLLAPUDI, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • TABLET CONTAINING VALSARTAN AND SACUBITRIL
    Publication number: 20200276129
    Abstract: The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesoporous inorganic stabilizer, e.g. mesoporous silica (Syloid®).
    Type: Application
    Filed: October 12, 2018
    Publication date: September 3, 2020
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Bala Ramesha Chary RALLABANDI, Vamshi Ramana PRATHAP, Krishna Mohan GOLLAPUDI, Bala Subramanian VELUSAMY, Srimannarayana BANDLA, Hendrik SCHLEHAHN, Dieter RUCHATZ
  • GASTRO-RESISTANT FORMULATION CONTAINING POSACONAZOLE
    Publication number: 20180228798
    Abstract: The present invention relates to a gastro-resistant pharmaceutical composition comprising a solid solution prepared by hot-melt extrusion, whereby the solid solution contains posaconazole, an enteric polymer and a non-enteric polymer. The composition is preferably a granulate material that can be filled into a capsule or compressed into a tablet.
    Type: Application
    Filed: July 21, 2016
    Publication date: August 16, 2018
    Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG)
    Inventors: Vamshi Ramana PRATHAP, Venkatasimhadri Naidu KALAMATA, Bala Ramesha Chary RALLABANDI, Vinay Kumar KATAKAM, Hendrik SCHLEHAHN