Patents by Inventor Van J. Wedeen

Van J. Wedeen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150363951
    Abstract: A system and method includes acquiring image data of the subject that includes information about the white matter tissue in the brain of the subject having diffusion information. An image of the subject is reconstructed from the image data that depicts the white matter tissue. A coordinate system information is produced by correlating the white matter tissue in the reconstructed image with a coordinate system in which the white matter tissue is arranged in an orthogonal grid. A deviation of the white matter tissue from the orthogonal grid is determined. Fiber paths of the white matter tissue are built by applying a bias against information determined to be associated with a deviation of the white matter tissue from the orthogonal grid.
    Type: Application
    Filed: January 31, 2014
    Publication date: December 17, 2015
    Inventor: Van J. WEDEEN
  • Patent number: 8355772
    Abstract: A method for processing MRI data in which a reference direction and a first voxel are selected. A first transverse orientation vector associated with the first voxel is determined. This first transverse orientation vector is normal to the reference direction. On the basis of the first transverse orientation vector, a second voxel is selected. A second transverse orientation vector associated with the second voxel is also selected. This second transverse orientation vector is likewise normal to the reference direction. The method also includes determining whether a relationship between the first and second transverse orientation vectors is consistent with a track normal to the reference direction and extending between the first and second voxels.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: January 15, 2013
    Assignee: The General Hospital Corporation
    Inventor: Van J. Wedeen
  • Patent number: 7965881
    Abstract: A magnetic resonance imaging (MRI) method includes generating first and second spin populations within each of a plurality of pixels of a slice of an object. These spin populations have different phase histories. For each pixel, MRI signals from those spin populations are acquired at different times These MRI signals can then be used to determine a field strength difference between different pixels of the slice.
    Type: Grant
    Filed: May 16, 2005
    Date of Patent: June 21, 2011
    Assignee: The General Hospital Corporation
    Inventors: Timothy G. Reese, Van J. Wedeen
  • Patent number: 7928728
    Abstract: A method for displaying diffusion data includes defining intra-voxel coherence and inter-voxel coherence of the diffusion data. On the basis of the inter-voxel coherence and the intra-voxel coherence, a multiplicity of tracks can be defined. Only those tracks having a selected characteristic are displayed.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: April 19, 2011
    Assignee: the General Hospital Corporation
    Inventor: Van J. Wedeen
  • Patent number: 7511494
    Abstract: A diffusion-weighted MRI pulse sequence employs a two-dimensional diffusion weighting gradient that is sensitive to spin diffusion in a plane defined by two orthogonal gradients to acquire an image. The resulting magnitude image indicates the location of neuronal fibers perpendicular to this plane and by repeating the acquisition with the plane oriented at different angles, neuronal fibers extending through the field of view at any angle are detected. The magnitude images are used to produce a fiber tracking image.
    Type: Grant
    Filed: May 11, 2007
    Date of Patent: March 31, 2009
    Assignee: The General Hospital Corporation
    Inventor: Van J. Wedeen
  • Publication number: 20090037108
    Abstract: A method for processing MRI data in which a reference direction and a first voxel are selected. A first transverse orientation vector associated with the first voxel is determined. This first transverse orientation vector is normal to the reference direction. On the basis of the first transverse orientation vector, a second voxel is selected. A second transverse orientation vector associated with the second voxel is also selected. This second transverse orientation vector is likewise normal to the reference direction. The method also includes determining whether a relationship between the first and second transverse orientation vectors is consistent with a track normal to the reference direction and extending between the first and second voxels.
    Type: Application
    Filed: March 10, 2006
    Publication date: February 5, 2009
    Inventor: Van J. Wedeen
  • Publication number: 20080284434
    Abstract: A method for displaying diffusion data includes defining intra-voxel coherence and inter-voxel coherence of the diffusion data. On the basis of the inter-voxel coherence and the intra-voxel coherence, a multiplicity of tracks can be defined. Only those tracks having a selected characteristic are displayed.
    Type: Application
    Filed: March 10, 2006
    Publication date: November 20, 2008
    Inventor: Van J. Wedeen
  • Publication number: 20080240530
    Abstract: A magnetic resonance imaging (MRI) method includes generating first and second spin populations within each of a plurality of pixels of a slice of an object. These spin populations have different phase histories. For each pixel, MRI signals from those spin populations are acquired at different times These MRI signals can then be used to determine a field strength difference between different pixels of the slice.
    Type: Application
    Filed: May 16, 2005
    Publication date: October 2, 2008
    Inventors: Timothy G. Reese, Van J. Wedeen
  • Patent number: 7034531
    Abstract: A diffusion MRI technique that employs a sampling/reconstruction scheme that samples the diffusion signal directly on the sphere and reconstructs the diffusion function directly on the sphere is presented.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: April 25, 2006
    Assignee: The General Hospital Corporation
    Inventors: David S. Tuch, Van J. Wedeen
  • Patent number: 4901019
    Abstract: Images of, e.g., a vascular tree, are obtained in a shorter-than-usual time by deliberately undersampling the object, which results in aliasing, and then processing the undersampled data to eliminate the effects of the aliasing.
    Type: Grant
    Filed: August 18, 1986
    Date of Patent: February 13, 1990
    Assignee: The General Hospital Corporation
    Inventor: Van J. Wedeen
  • Patent number: 4752734
    Abstract: A nuclear magnetic resonance projection image of fluid flow in a vessel is obtained by generating two data sets encoded with phase information indicative of two different velocity profiles of the fluid (taken at different times), combining the data sets, and displaying the resulting data set as an image.
    Type: Grant
    Filed: February 24, 1987
    Date of Patent: June 21, 1988
    Assignee: The General Hospital Corporation
    Inventor: Van J. Wedeen
  • Patent number: 4625169
    Abstract: Nuclear magnetic resonance apparatus for forming an image representative of a velocity profile of a fluid flowing in a vessel in which the fluid is stimulated to produce a time-dependent magnetic resonance signal, Fourier-transformed data is derived from the time-dependent magnetic resonance signal, the stimulating is done so as to introduce, into a predetermined component of the Fourier-transformed data, spatially-dependent phase information indicative of the velocity profile of the fluid, and the predetermined component is extracted for display as the image representative of the velocity profile.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: November 25, 1986
    Assignee: The General Hospital Corporation
    Inventors: Van J. Wedeen, Bruce R. Rosen