Abstract: Techniques are disclosed for coding video in applications where regions of video are inactive on a frame to frame basis. According to the techniques, coding processes update and reconstruct only a subset of pixel blocks of pixels within a frame, while other pixel blocks are retained from a previously coded frame stored in a coder's or decoder's reference frame buffer. The technique is called Backward Reference Updating (or “BRU”) for convenience. At a desired pixel block granularity, based on the activity between a current frame to be coded and its reference frame(s), BRU will only perform prediction, transform, quantization, and reconstruction on selected regions that are determined to be active. The reconstructed pixels in these active regions are directly placed onto a specified reference frame in memory instead of creating a new frame. Therefore, fewer memory transfers need to be performed.

Abstract: Disclosed are anthranilic amide derivatives having the formula: Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.

Abstract: Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.

Abstract: Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.