Abstract: A therapeutic spectacles device for reliving symptoms of dry eye disease. The device includes a protective housing configured to house a stimulus mechanism and an internal power source; at least one contact pad attached to the protective housing; and an attachment mechanism arranged on the protective housing. The at least one contact pad is configured, to contact a targeted area within a region selected from patient's nasofrontal region, supraorbital region, suborbital region, temporal region, or any combination of the same. The attachment mechanism can be configured to fix the protective housing to the therapeutic spectacles device such that the at least one contact pad rests against the targeted, area, when the therapeutic spectacles device is fixed on spectacles worn by the patient. The stimulus mechanism can be configured to deliver a stimulus through the at least one contact pad to the targeted area.

Abstract: A dry adhesive article comprising: (i) a substrate comprising a primary surface and (ii) a layer of nanofibers disposed on the primary surface of the substrate in a random orientation, the layer comprising a polyacrylate block copolymer; wherein, the layer of nanofibers exhibit pressure-sensitive adhesion.

Abstract: Disclosed are ammunition and ammunition tracking systems. The ammunition and ammunition tracking system may include a first projectile and a marker. The marker may be associated with the first projectile. The marker may contain a unique signature such that the first projectile may be identifiable from a second projectile.

Abstract: Embodiments provide a moldable warming device is configured to provide, using a heating disc, therapeutic warmth and, using a harmonic RFSVG, tuned harmonic resonance frequency stimulation vibration according to determined tuning parameters across the contour of the entire surface of the user's eyelid and periorbital structures to induce expression of shear thinned and liquified meibum from each Meibomian gland in all four eyelids to improve the lipid layer of the surface of the user's eye tear film. According to an embodiment, the moldable warming device further includes a pair of removable and reusable eye pads, each eye pad including a miniaturized optical coherence tomography device configured to map, in real-time, a topography of the user's periocular surface, including a mapping of the eyes and the nose including interpupillary distance and corneal apex height above the lateral canthus to optimize conformance of the pair of eye pads to the periocular surface of the user's eyelids.

Abstract: Disclosed are ammunition and ammunition tracking systems. The ammunition and ammunition tracking system may include a first projectile and a marker. The marker may be associated with the first projectile. The marker may contain a unique signature such that the first projectile may be identifiable from a second projectile.

Abstract: Embodiments provide a moldable warming device, including a heating disc; a first harmonic resonance frequency stimulation vibration generator (RFSVG); a coupling device; a mask configured to hold the heating disc, the first harmonic RFSVG, and the coupling device for use in parallel utility; and a sensor array, the sensor array configured to determine tuning parameters of a vibration and heating profile of a user's individual eyelid, periorbital, and nasal three-dimensional anatomy and surface topography. According to at least one embodiment, the moldable warming device is configured to provide an eyelid surface and periorbital structures with therapeutic warmth, and the first harmonic RFSVG is configured to provide tuned harmonic resonance or non-resonance frequency stimulation vibration over the user's nasal bridge area through the user's nasal bone such that nasal sensory nerves are stimulated to induce tear production reflex in the user's lacrimal function unit.

Abstract: An accommodating contact lens comprises a control device, which comprises one or more eyelid engagement structures. The eyelid engagement structures are configured to move with the eyelid relative to the contact lens. The eyelid engagement structure is coupled to the eyelid and to the accommodating contact lens, which may comprise a fluidic module having inner and outer fluid reservoirs. The eyelid engagement structure is configured to respond to the narrowing or widening of the eyelid fissure, moving a fluid in or out of the inner reservoir to accommodate near or far vision.

Abstract: An accommodating contact lens comprises a control device, which comprises one or more eyelid engagement structures. The eyelid engagement structures are configured to move with the eyelid relative to the contact lens. The eyelid engagement structure is coupled to the eyelid and to the accommodating contact lens, which may comprise a fluidic module having inner and outer fluid reservoirs. The eyelid engagement structure is configured to respond to the narrowing or widening of the eyelid fissure, moving a fluid in or out of the inner reservoir to accommodate near or far vision.

Abstract: The invention provides methods and lenses for reducing asthenopia related symptoms associated with proprioceptive disparity. In certain aspects, lenses of the invention include a distance portion and a near portion, and a progressive increase in minus power from the distance portion to the near portion. Additionally, lenses of the invention may include a prism and a progressive reduction in optical power, in which the prism and the progressive reduction are varied independently. In one embodiment, a lens is provided that has a base-in prism and that provides an increase in minus power from the distance vision portion of the lens to a near vision portion of the lens (i.e., a progressive reduction).

Abstract: There is disclosed herein a system for measuring visual fixation disparity comprising a display apparatus for presenting stereoscopic visual content to a patient. A sensing apparatus tracks eye movement of the patient. A controller controls the display apparatus to stereoscopically display a central image target alternately to a left eye and a right eye of the patient and tracking eye movement for a period of time as the central image target is alternated between the left eye and the right eye, and incrementally relocating the central image target left and right images until the patient perceives the left and right images to be physically coincident.

Abstract: Methods of stabilizing collagen fibrils in a cornea are disclosed. The stabilization may be effected by treating the cornea with a protein that crosslinks collagen fibrils, such as decorin. The stablization methods include treatment of corneas before, during, or after a surgical procedure, treatment of keratectasia, and treatment of keratoconus.

Abstract: There is disclosed herein a system for measuring visual fixation disparity comprising a display apparatus for presenting stereoscopic visual content to a patient. A sensing apparatus tracks eye movement of the patient. A controller controls the display apparatus to stereoscopically display a central image target alternately to a left eye and a right eye of the patient and tracking eye movement for a period of time as the central image target is alternated between the left eye and the right eye, and incrementally relocating the central image target left and right images until the patient perceives the left and right images to be physically coincident.

Abstract: Systems and methods include a cutting instrument that creates incisions in selected areas of the cornea; an eye therapy system that applies reshaping forces to the cornea; and a controller that determines the selected areas of the cornea for the incisions and the reshaping forces from the eye therapy system, such that the reshaping forces and the incisions combine to achieve corrective reshaping of the cornea. Other systems and methods include measuring an eye to determine a required amount of reshaping of a cornea; determining one or more doses of cross-linking agent and one or more corresponding doses of photoactivating light according to the required amount of reshaping; applying the cross-linking agent to the cornea; and delivering, from a light source, the photoactivating light to the area of the eye, the photoactivating light combining with the cross-linking agent to induce the corrective reshaping of the cornea.

Abstract: The invention provides methods and lenses for reducing asthenopia related symptoms associated with proprioceptive disparity. In certain aspects, lenses of the invention include a distance portion and a near portion, and a progressive increase in minus power from the distance portion to the near portion. Additionally, lenses of the invention may include a prism and a progressive reduction in optical power, in which the prism and the progressive reduction are varied independently. In one embodiment, a lens is provided that has a base-in prism and that provides an increase in minus power from the distance vision portion of the lens to a near vision portion of the lens (i.e., a progressive reduction).

Abstract: A system for aligning an eye therapy instrument over a selected area or feature of an eye provides an attachment element that is removably attached to a surface of an eye. A receiving element is coupled to the attachment element and movable relative to the attachment element. The receiving element includes a coupling element configured to operably couple an eye therapy instrument to the receiving element and adjustably move the eye therapy instrument into a selected position with respect to the attachment element. The system makes adjustments to ensure accurate delivery of treatment from the eye therapy device to areas of the eye. In one embodiment, the receiving element allows lateral adjustments to be made along one or more axes. Additionally or alternatively, the receiving element allows angular or rotational adjustments to be made about one or more axes.

Abstract: Methods of stabilizing and organizing collagen fibrils in extracellular matrix of retinal tissues, particularly Bruch's membranes, and stabilizing retinal pigment epithelial layers lining Bruch's membrane are disclosed. The stabilization and organization may be effected by treating retinal tissues with a protein that crosslinks and organizes collagen fibrils, such as decorin. The stabilization and organization methods include treatment of retinal tissues before, during, or after diagnosis of dry macular degeneration, diagnosis of early stages of diabetic retinopathy and diabetic macular edema to prevent, retard, or limit progression of disorganization of Bruch's membrane and disorganization of retinal pigment epithelial cells lining Bruch's membrane.

Abstract: Systems and methods include a cutting instrument that creates incisions in selected areas of the cornea; an eye therapy system that applies reshaping forces to the cornea; and a controller that determines the selected areas of the cornea for the incisions and the reshaping forces from the eye therapy system, such that the reshaping forces and the incisions combine to achieve corrective reshaping of the cornea. Other systems and methods include measuring an eye to determine a required amount of reshaping of a cornea; determining one or more doses of cross-linking agent and one or more corresponding doses of photoactivating light according to the required amount of reshaping; applying the cross-linking agent to the cornea; and delivering, from a light source, the photoactivating light to the area of the eye, the photoactivating light combining with the cross-linking agent to induce the corrective reshaping of the cornea.

Abstract: A system for aligning an eye therapy instrument over a selected area or feature of an eye provides an attachment element that is removably attached to a surface of an eye. A receiving element is coupled to the attachment element and movable relative to the attachment element. The receiving element includes a coupling element configured to operably couple an eye therapy instrument to the receiving element and adjustably move the eye therapy instrument into a selected position with respect to the attachment element. The system makes adjustments to ensure accurate delivery of treatment from the eye therapy device to areas of the eye. In one embodiment, the receiving element allows lateral adjustments to be made along one or more axes. Additionally or alternatively, the receiving element allows angular or rotational adjustments to be made about one or more axes.

Abstract: Methods of stabilizing collagen fibrils in a cornea are disclosed. The stabilization may be effected by treating the cornea with a protein that crosslinks collagen fibrils, such as decorin. The stablization methods include treatment of corneas before, during, or after a surgical procedure, treatment of keratectasia, and treatment of keratoconus.