Patents by Inventor Vancheswaran GOPALAKRISHNAN

Vancheswaran GOPALAKRISHNAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR ENHANCING IMMUNE CHECKPOINT BLOCKADE THERAPY BY MODULATING THE MICROBIOME
    Publication number: 20230109343
    Abstract: Provided herein are methods and compositions for the treatment of cancer by modulating the microbiome to enhance the efficacy of immune checkpoint blockade. The microbiome may be modulated by the administration of butyrate and/or butyrate-producing bacteria. Also provided herein are methods of determining a response to an immune checkpoint inhibitor by identifying if a subject has a favorable microbial profile.
    Type: Application
    Filed: July 22, 2022
    Publication date: April 6, 2023
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jennifer WARGO, Vancheswaran GOPALAKRISHNAN
  • Methods for enhancing immune checkpoint blockade therapy by modulating the microbiome
    Patent number: 11395838
    Abstract: Provided herein are methods and compositions for the treatment of cancer by modulating the microbiome to enhance the efficacy of immune checkpoint blockade. The microbiome may be modulated by the administration of butyrate and/or butyrate-producing bacteria. Also provided herein are methods of determining a response to an immune checkpoint inhibitor by identifying if a subject has a favorable microbial profile.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: July 26, 2022
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jennifer Wargo, Vancheswaran Gopalakrishnan
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20220016188
    Abstract: Described herein are methods and compositions for treating cancer and for predicting a subjects' response to combination checkpoint inhibitor therapy.
    Type: Application
    Filed: November 21, 2019
    Publication date: January 20, 2022
    Inventors: Jennifer A. WARGO, Vancheswaran GOPALAKRISHNAN, Miles C. ANDREWS, Laurence ZITVOGEL, Valerio IEBBA
  • TREATMENT OF A CANCER BY MICROBIOME MODULATION
    Publication number: 20210361721
    Abstract: Methods are provided for identifying donors of fecal matter that can improve a subject's response to a checkpoint inhibitor in the treatment of cancer. Methods and compositions are also provided for using donated fecal matter in the treatment of cancer.
    Type: Application
    Filed: March 28, 2019
    Publication date: November 25, 2021
    Inventors: Jennifer WORTMAN, Diao LIYANG, Christopher DESJARDINS, Georgios MARNELLOS, Matthew HENN, Jennifer WARGO, Vancheswaran GOPALAKRISHNAN
  • METHODS FOR ENHANCING IMMUNE CHECKPOINT BLOCKADE THERAPY BY MODULATING THE MICROBIOME
    Publication number: 20200129569
    Abstract: Provided herein are methods and compositions for the treatment of cancer by modulating the microbiome to enhance the efficacy of immune checkpoint blockade. The microbiome may be modulated by the administration of butyrate and/or butyrate-producing bacteria. Also provided herein are methods of determining a response to an immune checkpoint inhibitor by identifying if a subject has a favorable microbial profile.
    Type: Application
    Filed: September 27, 2017
    Publication date: April 30, 2020
    Inventors: Jennifer WARGO, Vancheswaran GOPALAKRISHNAN