Patents by Inventor Vanessa O. Grabbe

Vanessa O. Grabbe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that inhibit the binding of integrins to their receptors
    Patent number: 6262084
    Abstract: A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions thereof; and the use of the compounds either as above, or in formulations for the control or prevention of diseases states in which &agr;4&bgr;1 is involved.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: July 17, 2001
    Assignee: Texas Biotechnology Corporation
    Inventors: Ronald J. Biediger, Vanessa O. Grabbe, George W. Holland, Jamal Kassir, Karin M. Keller, Timothy P. Kogan, Shuqun Lin, Robert V. Market, Bore G. Raju, Ian L. Scott, Chengde Wu
  • N, N-disubstituted amides that inhibit the binding of integrins to their receptors
    Patent number: 6194448
    Abstract: A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which &agr;4&bgr;1 is involved.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: February 27, 2001
    Assignee: Texas Biotechnology Corporation
    Inventors: Ronald J. Biediger, Vanessa O. Grabbe, George W. Holland, Jamal M. Kassir, Timothy P. Kogan, Shuqun Lin, Robert V. Market, Bore G. Raju, Ian L. Scott, Chengde Wu
  • Compounds that inhibit the binding of integrins to their receptors
    Patent number: 6096773
    Abstract: A method for the inhibition of the binding of .alpha..sub.4 .beta..sub.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which .alpha..sub.4 .beta..sub.1 is involved.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: August 1, 2000
    Assignee: Texas Biotechnology Corporation, Inc.
    Inventors: Ian L. Scott, Bore G. Raju, Ronald J. Biediger, Vanessa O. Grabbe, Jamal Kassir, Karin M. Keller, Timothy P. Kogan, deceased, Shuqun Lin, Robert V. Market