Patents by Inventor Vania E. Kenanova

Vania E. Kenanova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN PROTEIN SCAFFOLD WITH CONTROLLED SERUM PHARMACOKINETICS
    Publication number: 20160083450
    Abstract: This invention provides constructs comprising a protein scaffold, wherein the scaffold comprises Domain III, Domain IIIa, or Domain IIIb of human serum albumin or a polypeptide having substantial sequence identity to the Domain III, the Domain IIIa, or the Domain IIIb; and a targeting moiety in covalent linkage to the protein scaffold; and a therapeutic moiety and/or an imaging moiety in covalent linkage to the protein scaffold. The scaffold can be modified to tune the serum pharmacokinetics of the construct. In addition to methods of making the constructs, therapeutic, imaging and diagnostic uses of the constructs are also provided.
    Type: Application
    Filed: February 5, 2015
    Publication date: March 24, 2016
    Inventors: Anna M. WU, Vania E. Kenanova, Tove Olafsen
  • HUMAN PROTEIN SCAFFOLD WITH CONTROLLED SERUM PHARMACOKINETICS
    Publication number: 20120076728
    Abstract: This invention provides constructs comprising a protein scaffold, wherein the scaffold comprises Domain III, Domain IIIa, or Domain IIIb of human serum albumin or a polypeptide having substantial sequence identity to the Domain III, the Domain IIIa, or the Domain IIIb; and a targeting moiety in covalent linkage to the protein scaffold; and a therapeutic moiety and/or an imaging moiety in covalent linkage to the protein scaffold. The scaffold can be modified to tune the serum pharmacokinetics of the construct. In addition to methods of making the constructs, therapeutic, imaging and diagnostic uses of the constructs are also provided.
    Type: Application
    Filed: April 7, 2010
    Publication date: March 29, 2012
    Applicant: The Regents of the University of California
    Inventors: Anna M. Wu, Vania E. Kenanova, Tove Olafsen