Patents by Inventor Vaniambadi Kalyanaraman

Vaniambadi Kalyanaraman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Truncated HIV envelope proteins (ENV), methods and compositions related thereto
    Patent number: 10081658
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: September 25, 2018
    Assignees: Advanced BioScience Laboratories, Inc., The United States of America as Represented by the Secretary of the Army, The Henry M. Jackson Foundation for the Advancement of Military Medicines, Inc.
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. VanCott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • TRUNCATED HIV ENVELOPE PROTEINS (ENV), METHODS AND COMPOSITIONS RELATED THERETO
    Publication number: 20140220107
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 7, 2014
    Applicants: ADVANCED BIOSCIENCE LABORATORIES, INC., HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, THE GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. Vancott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • POLYVALENT, PRIMARY HIV-1 GLYCOPROTEIN DNA VACCINES AND VACCINATION METHODS
    Publication number: 20110171258
    Abstract: Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The compositions and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods for using the protein compositions as boosts following administration of the DNA compositions are provided.
    Type: Application
    Filed: February 3, 2011
    Publication date: July 14, 2011
    Applicants: UNIVERSITY OF MASSACHUSETTS, ADVANCED BIOSCIENCE LABORATORIES, INC.
    Inventors: Shan Lu, Shixia Wang, Ranajit Pal, Vaniambadi Kalyanaraman, Stephen Charles Whitney, Tim Keen, Balachandran Nair, Phillip Markham
  • Polyvalent, primary HIV-1 glycoprotein DNA vaccines and vaccination methods
    Patent number: 7901690
    Abstract: Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The composition and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods fro using the protein compositions as boosts following administration of the DNA compositions are provided.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: March 8, 2011
    Assignees: University of Massachusetts, Advanced Bioscience Laboratories
    Inventors: Shan Lu, Shixia Wang, Ranajit Pal, Vaniambadi Kalyanaraman, Stephen Charles Whitney, Tim Keen, Balachandran Nair, Phillip Markham
  • Mutant viral nucleic acids and vaccine containing same
    Publication number: 20050220816
    Abstract: The present invention is directed to a nucleic acid comprising a deletion mutant of a PTAP (SEQ ID NO:1) motif and/or PPXY (SEQ ID NO:2) and/or YXXL (SEQ ID NO:3) motif in the late or L domain of a viral protein, where the L domain mediates the budding process. Examples of such viral proteins containing L domains are the retroviral gag proteins and the matrix proteins of rhabdoviruses and filoviruses. In addition, the present invention is directed to a vector containing (a) this nucleic acid or (b) this nucleic acid and one or more nucleic acids encoding other structural and regulatory viral proteins. The present invention is further directed to vaccines containing the nucleic acid or vector for the purpose of augmenting a cellular immune response.
    Type: Application
    Filed: March 31, 2004
    Publication date: October 6, 2005
    Inventors: Anthony Cristillo, Vaniambadi Kalyanaraman, Ranajit Pal
  • Polyvalent, primary HIV-1 glycoprotein DNA vaccines and vaccination methods
    Publication number: 20040191269
    Abstract: Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The compositions and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods for using the protein compositions as boosts following administration of the DNA compositions are provided.
    Type: Application
    Filed: December 3, 2003
    Publication date: September 30, 2004
    Inventors: Shan Lu, Shixia Wang, Ranajit Pal, Vaniambadi Kalyanaraman, Stephen Charles Whitney, Tim Keen, Balachandran Nair, Phillip Markham