Patents by Inventor Vanitha Thulasiraman

Vanitha Thulasiraman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and system for multiplexed time-resolved fluorescence detection
    Patent number: 10379046
    Abstract: The present invention is directed to a novel method to multiplex long lifetime fluorescent dyes using time-resolved fluorescence (TRF) detection. A combination of spectral and temporal differences in fluorescence emission is used to enhance the ability to separate signals in an assay from multiple dyes. Multiplexed TRF detection apparatuses and systems configured for performing all or part of any of the methods disclosed herein are also provided, particularly apparatuses and systems incorporating cartridge-based multi-mode readers.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: August 13, 2019
    Assignee: Molecular Devices, LLC
    Inventors: Michael Katzlinger, Evan F. Cromwell, Vanitha Thulasiraman
  • METHOD AND SYSTEM FOR MULTIPLEXED TIME-RESOLVED FLUORESCENCE DETECTION
    Publication number: 20160299076
    Abstract: The present invention is directed to a novel method to multiplex long lifetime fluorescent dyes using time-resolved fluorescence (TRF) detection. A combination of spectral and temporal differences in fluorescence emission is used to enhance the ability to separate signals in an assay from multiple dyes. Multiplexed TRF detection apparatuses and systems configured for performing all or part of any of the methods disclosed herein are also provided, particularly apparatuses and systems incorporating cartridge-based multi-mode readers.
    Type: Application
    Filed: April 8, 2015
    Publication date: October 13, 2016
    Inventors: Michael Katzlinger, Evan F. Cromwell, Vanitha Thulasiraman
  • Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry
    Publication number: 20070059776
    Abstract: The invention provides methods of monitoring the production of a target polypeptide by generating surface enhanced laser desorption/ionization mass spectral profiles of samples taken from multiple cell culture batches or of samples taken at different times from a given batch. The invention additionally provides methods for monitoring the purification of a target polypeptide from a mixture by generating surface enhanced laser desorption/ionization mass spectral profiles of samples taken at various times during a purification process. In addition, the invention relates to methods of identifying conditions that can be used in increasing the scale of a given purification process.
    Type: Application
    Filed: August 3, 2006
    Publication date: March 15, 2007
    Inventors: Egisto Boschetti, Lisa Bradbury, Huw Davies, Lee Lomas, Thang Pham, Vanitha Thulasiraman, Tai-Tung Yip
  • Detection of kinase substrates and products using ion mass spectrometry
    Publication number: 20040029191
    Abstract: The present invention provides materials and methods for simultaneously analyzing multiple kinase substrates and products using mass spectrometry.
    Type: Application
    Filed: May 16, 2003
    Publication date: February 12, 2004
    Applicant: Ciphergen Biosystems, Inc.
    Inventors: Lee Lomas, Vanitha Thulasiraman, Tai-Tung Yip
  • Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry
    Publication number: 20030091976
    Abstract: The invention provides methods of monitoring the production of a target polypeptide by generating surface enhanced laser desorption/ionization mass spectral profiles of samples taken from multiple cell culture batches or of samples taken at different times from a given batch. The invention additionally provides methods for monitoring the purification of a target polypeptide from a mixture by generating surface enhanced laser desorption/ionization mass spectral profiles of samples taken at various times during a purification process. In addition, the invention relates to methods of identifying conditions that can be used in increasing the scale of a given purification process.
    Type: Application
    Filed: April 16, 2002
    Publication date: May 15, 2003
    Applicant: Ciphergen Biosystems, Inc.
    Inventors: Egisto Boschetti, Lisa Bradbury, Huw Davies, Lee O. Lomas, Thang T. Pham, Vanitha Thulasiraman, Tai-Tung Yip