Patents by Inventor Vanja M. King
Vanja M. King has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9775800Abstract: Effective treatments of pain that accompanies post-operative surgeries are provided. Through the administration of an effective amount of a combination of bupivacaine and clonidine at or near a target site, one can alleviate or prevent pain. This administration of bupivacaine and clonidine or pharmaceutically acceptable salts thereof is particularly useful following surgery.Type: GrantFiled: September 11, 2015Date of Patent: October 3, 2017Assignee: Warsaw Orthopedic, Inc.Inventors: Phillip E. McDonald, Amira Wohabrebbi, Christopher M. Hobot, Vanja M. King
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Patent number: 9700567Abstract: Effective treatments of acute pain for extended periods of time are provided. Through the administration of an effective amount of dexamethasone at or near a target site, one can relieve pain cause by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: GrantFiled: October 30, 2014Date of Patent: July 11, 2017Assignee: Warsaw Orthopedic, Inc.Inventors: John M. Zanella, Vanja M. King, Christopher M. Hobot, Stephen M. Cox, William F. McKay, Kathy L. Remsen
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Patent number: 9492461Abstract: Methods and compositions are provided for treating an intervertebral disc herniation by local administration of one or more biodegradable drug depots comprising a therapeutically effective amount of a glucocorticoid at or near the intervertebral disc herniation to reduce the size of the intervertebral disc herniation.Type: GrantFiled: March 2, 2009Date of Patent: November 15, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Vanja M. King, John M. Zanella, Jared Wilsey
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Patent number: 9289409Abstract: Effective treatments of pain and/or inflammation for extended periods of time are provided. Through the administration of an effective amount of sulindac or a pharmaceutically acceptable salt thereof at or near a target site, one can relieve pain and/or inflammation caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days, at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: GrantFiled: March 27, 2009Date of Patent: March 22, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: John Myers Zanella, Vanja M King, Christopher M Hobot, S Mark Cox, Danielle Biggs, Katara Shaw, William F McKay, Kathy L Remsen
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Publication number: 20160000705Abstract: Effective treatments of pain that accompanies post-operative surgeries are provided. Through the administration of an effective amount of a combination of bupivacaine and clonidine at or near a target site, one can alleviate or prevent pain. This administration of bupivacaine and clonidine or pharmaceutically acceptable salts thereof is particularly useful following surgery.Type: ApplicationFiled: September 11, 2015Publication date: January 7, 2016Inventors: Phillip E. McDonald, Amira Wohabrebbi, Christopher M. Hobot, Vanja M. King
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Patent number: 9132085Abstract: Effective treatments of pain that accompanies post-operative surgeries are provided. Through the administration of an effective amount of a combination of bupivacaine and clonidine at or near a target site, one can alleviate or prevent pain. This administration of bupivacaine and clonidine or pharmaceutically acceptable salts thereof is particularly useful following surgery.Type: GrantFiled: April 8, 2009Date of Patent: September 15, 2015Assignee: Warsaw Orthopedic, Inc.Inventors: Phillip E. McDonald, Amira Wohabrebbi, Christopher M. Hobot, Vanja M. King
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Patent number: 9125917Abstract: Effective treatments of pain and inflammation are provided. Through the administration of an effective amount of fluocinolone at or near a target site, one can reduce, prevent or treat inflammation and pain and autoimmune disorders. In various embodiments, fluocinolone formulations may be provided within biodegradable polymers to reduce, prevent or treat sciatic pain and/or inflammation. In various embodiments, prevent transplant rejection for at least twenty-five days. In some embodiments, the pain relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: GrantFiled: March 27, 2009Date of Patent: September 8, 2015Assignees: Warsaw Orthopedic, Inc., Medtronic, Inc.Inventors: William F McKay, Christopher M Hobot, Danielle Biggs, Katara Shaw, John Myers Zanella, Vanja M King, Stephen Mark Cox, Kathy L Remsen
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Publication number: 20150065474Abstract: Effective treatments of acute pain for extended periods of time are provided. Through the administration of an effective amount of dexamethasone at or near a target site, one can relieve pain cause by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: ApplicationFiled: October 30, 2014Publication date: March 5, 2015Inventors: John M. Zanella, Vanja M. King, Christopher M. Hobot, Stephen M. Cox, William F. McKay, Kathy L. Remsen
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Patent number: 8877226Abstract: Effective treatments of acute pain for extended periods of time are provided. Through the administration of an effective amount of dexamethasone at or near a target site, one can relieve pain cause by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: GrantFiled: May 30, 2013Date of Patent: November 4, 2014Assignees: Medtronic, Inc., Warsaw Orthopedic, Inc.Inventors: John M. Zanella, Vanja M. King, Christopher M. Hobot, Stephen M. Cox, William F. McKay, Kathy L. Remsen
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Publication number: 20130261095Abstract: Effective treatments of acute pain for extended periods of time are provided. Through the administration of an effective amount of dexamethasone at or near a target site, one can relieve pain cause by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: ApplicationFiled: May 30, 2013Publication date: October 3, 2013Inventors: John M. Zanella, Vanja M. King, Christopher M. Hobot, Stephen M. Cox, William F. McKay, Kathy L. Remsen
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Patent number: 7723291Abstract: A pump to deliver bone-growth factors to a carrier matrix within a patient. Pump can be internal or external. With external pumps, additional amounts of the same growth factor may be added, or the bioactive agent may be changed during the course of treatment. An external pump permits the use of cells to promote bone growth. The pump can have several reservoirs and the pump can itself be received in the carrier matrix with an outlet tube or other structure to defuse the growth factors into the carrier matrix. The pump protocol can be used for slow-to-heal fractures, such as closed fractures, and can be used for slow-to-heal patients.Type: GrantFiled: July 27, 2006Date of Patent: May 25, 2010Inventors: Neil Beals, Jeffrey L. Scifert, Vanja M. King
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Publication number: 20090264478Abstract: Effective treatments of acute pain and/or inflammation for extended periods of time are provided. Through the administration of an effective amount of sulfasalazine at or near a target site, one can relieve pain caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discogenic back pain and joint pain as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: ApplicationFiled: April 18, 2008Publication date: October 22, 2009Applicant: Warsaw Orthopedic, Inc.Inventors: Stephen M. Cox, Christopher M. Hobot, John M. Zanella, Vanja M. King, William F. McKay, Kathy L. Remsen
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Publication number: 20090263444Abstract: Effective treatments of pain and inflammation are provided. Through the administration of an effective amount of fluocinolone at or near a target site, one can reduce, prevent or treat inflammation and pain and autoimmune disorders. In various embodiments, fluocinolone formulations may be provided within biodegradable polymers to reduce, prevent or treat sciatic pain and/or inflammation. In various embodiments, prevent transplant rejection for at least twenty-five days. In some embodiments, the pain relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: ApplicationFiled: March 27, 2009Publication date: October 22, 2009Applicants: WARSAW ORTHOPEDIC, INC., MEDTRONIC, INC.Inventors: William F. McKay, Christopher M. Hobot, Danielle Biggs, Katara Shaw, John Myers Zanella, Vanja M. King, Stephen Mark Cox, Kathy L. Remsen
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Publication number: 20090263451Abstract: Effective treatments of myofascial pain and/or inflammation are provided. Through the administration of an effective amount of at least one anti-inflammatory agent and/or analgesic at or near a target site, one can reduce, prevent or treat myofascial pain and/or inflammation.Type: ApplicationFiled: April 14, 2009Publication date: October 22, 2009Applicant: Warsaw Orthopedic, Inc.Inventor: Vanja M. King
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Publication number: 20090263459Abstract: Methods and compositions are provided for treating an intervertebral disc herniation by local administration of one or more biodegradable drug depots comprising a therapeutically effective amount of a glucocorticoid at or near the intervertebral disc herniation to reduce the size of the intervertebral disc herniation.Type: ApplicationFiled: March 2, 2009Publication date: October 22, 2009Applicant: WARSAW ORTHOPEDIC, INC.Inventors: Vanja M. King, John M. Zanella, Jared Wilsey
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Publication number: 20090263321Abstract: Effective treatments of pain that accompanies post-operative surgeries are provided. Through the administration of an effective amount of a combination of bupivacaine and clonidine at or near a target site, one can alleviate or prevent pain. This administration of bupivacaine and clonidine or pharmaceutically acceptable salts thereof is particularly useful following surgery.Type: ApplicationFiled: April 8, 2009Publication date: October 22, 2009Applicants: Warsaw Orthopedic, Inc., Medtronic, Inc.Inventors: Phillip E. McDonald, Amira Wohabrebbi, Christopher M. Hobot, Vanja M. King
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Publication number: 20090264531Abstract: Effective treatments of pain and/or inflammation for extended periods of time are provided. Through the administration of an effective amount of sulindac or a pharmaceutically acceptable salt thereof at or near a target site, one can relieve pain and/or inflammation caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days, at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.Type: ApplicationFiled: March 27, 2009Publication date: October 22, 2009Applicants: WARSAW ORTHOPEDIC, INC., MEDTRONIC, INC.Inventors: John M. Zanella, Vanja M. King, Christopher M. Hobot, S. Mark Cox, Danielle Biggs, Katara Shaw, William F. McKay, Kathy L. Remsen
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Publication number: 20080025987Abstract: A pump to deliver bone-growth factors to a carrier matrix within a patient. Pump can be internal or external. With external pumps, additional amounts of the same growth factor may be added, or the bioactive agent may be changed during the course of treatment. An external pump permits the use of cells to promote bone growth. The pump can have several reservoirs and the pump can itself be received in the carrier matrix with an outlet tube or other structure to defuse the growth factors into the carrier matrix. The pump protocol can be used for slow-to-heal fractures, such as closed fractures, and can be used for slow-to-heal patients.Type: ApplicationFiled: July 27, 2006Publication date: January 31, 2008Inventors: Neil Beals, Jeffrey L. Scifert, Vanja M. King
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Patent number: 6413531Abstract: A method for increasing the effectiveness of a biocide is described. In the method, at least one biocide and at least one diethanolamide are applied to a substrate or aqueous system subject to the growth of microorganisms. The diethanolamide is applied in an amount effective to increase the biocidal activity of the biocide. Biocidal compositions are described where the biocide and the diethanolamide are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates and in various aqueous systems are also described. The combination of the biocide and the diethanolamide is particularly useful as a biocide in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in industrial process waters.Type: GrantFiled: May 22, 2001Date of Patent: July 2, 2002Assignee: Buckman Laboratories International, Inc.Inventors: Vanja M. King, Marilyn S. Whittemore, Xiangdon Zhou
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Publication number: 20010031775Abstract: A method for increasing the effectiveness of a biocide is described. In the method, at least one biocide and at least one diethanolamide are applied to a substrate or aqueous system subject to the growth of microorganisms. The diethanolamide is applied in an amount effective to increase the biocidal activity of the biocide. Biocidal compositions are described where the biocide and the diethanolamide are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates and in various aqueous systems are also described. The combination of the biocide and the diethanolamide is particularly useful as a biocide in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in industrial process waters.Type: ApplicationFiled: May 22, 2001Publication date: October 18, 2001Applicant: Buckman Laboratories International, Inc.Inventors: Vanja M. King, Marilyn S. Whittemore, Xiangdong Zhou