Patents by Inventor Vanja Vela

Vanja Vela has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrolides with Anti-Inflammatory Activity
    Publication number: 20120058963
    Abstract: The present invention relates to novel semi-synthetic macrolides having anti-inflammatory activity. More particularly, the invention relates to 14- and 15-membered macrolides substituted at the 4? position, to their pharmaceutically acceptable derivatives, to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their activity and use in the treatment of inflammatory diseases and conditions in humans and animals, especially those diseases associated with excessive secretion of TNF-?, IL-1, IL-8, IL-2 or IL-5; and/or inhibitor of excessive lymphocyte proliferation; and/or excessive granulocyte degranulation.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 8, 2012
    Applicant: Glaxo Group Limited
    Inventors: Sulejman Alihodzic, Martina Bosnar, Ognjen Culic, Vesna Erakovic Haber, Antun Hutinec, Dubravko Jelic, Goran Kragol, Nikola Marjanovic, Zorica Marusic-Istuk, Marija Ribic, Vanja Vela
  • Macrolides with anti-inflammatory activity
    Patent number: 8080529
    Abstract: The present invention relates to novel semi-synthetic macrolides having anti-inflammatory activity. More particularly, the invention relates to 14- and 15-membered macrolides substituted at the 4? position, to their pharmaceutically acceptable derivatives, to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their activity and use in the treatment of inflammatory diseases and conditions in humans and animals, especially those diseases associated with excessive secretion of TNF-?, IL-1, IL-8, IL-2 or IL-5; and/or inhibitor of excessive lymphocyte proliferation; and/or excessive granulocyte degranulation.
    Type: Grant
    Filed: January 13, 2006
    Date of Patent: December 20, 2011
    Assignee: Glaxo Group Limited
    Inventors: Sulejman Alihodzic, Martina Bosnar, Ognjen Culic, Vesna Erakovic Haber, Antun Hutinec, Dubravko Jelic, Goran Kragol, Nikola Marjanovic, Zorica Marusic-Istuk, Marija Ribic, Vanja Vela
  • Decladinosyl-macrolides with anti-inflammatory activity
    Patent number: 7910559
    Abstract: The present invention relates to novel semi-synthetic macrolides having anti-inflammatory activity. More particularly, the invention relates to 14- and 15-membered macrolides lacking cladinose sugar substituted at the C-3 position, to their pharmaceutically acceptable derivatives, to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their activity and use in the treatment of inflammatory diseases and conditions in humans and animals, especially those diseases associated with excessive secretion of TNF-?, IL-1, IL-6, IL-8, IL-2 or IL-5; and/or inhibitor of excessive lymphocyte proliferation; and/or excessive granulocyte degranulation.
    Type: Grant
    Filed: January 13, 2006
    Date of Patent: March 22, 2011
    Assignee: GlaxoSmithKline istrazivacki centar Zagreb d.o.o.
    Inventors: Ognjen Culic, Martina Bosnar, Sulejman Alihodzic, Gorjana Lazarevski, Zorica Marusic Istuk, Antun Hutinec, Vanja Vela, Goran Kragol
  • Decladinosyl-Macrolides With Anti-Inflammatory Activity
    Publication number: 20080234211
    Abstract: The present invention relates to novel semi-synthetic macrolides having anti-inflammatory activity. More particularly, the invention relates to 14- and 15-membered macrolides lacking cladinose sugar substituted at the C-3 position, to their pharmaceutically acceptable derivatives, to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their activity and use in the treatment of inflammatory diseases and conditions in humans and animals, especially those diseases associated with excessive secretion of TNF-?, IL-1, IL-6, IL-8, IL-2 or IL-5; and/or inhibitor of excessive lymphocyte proliferation; and/or excessive granulocyte degranulation.
    Type: Application
    Filed: January 13, 2006
    Publication date: September 25, 2008
    Applicant: GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O.
    Inventors: Ognjen Culic, Martina Bosnar, Sulejman Alihodzic, Gorjana Lazarevski, Zorica Marusic Istuk, Antun Hutinec, Vanja Vela, Goran Kragol
  • Macrolides With Anti-Inflammatory Activity
    Publication number: 20080221046
    Abstract: The present invention relates to novel semi-synthetic macrolides having anti-inflammatory activity. More particularly, the invention relates to 14- and 15-membered macrolides substituted at the 4? position, to their pharmaceutically acceptable derivatives, to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their activity and use in the treatment of inflammatory diseases and conditions in humans and animals, especially those diseases associated with excessive secretion of TNF-?, IL-1, IL-8, IL-2 or IL-5; and/or inhibitor of excessive lymphocyte proliferation; and/or excessive granulocyte degranulation.
    Type: Application
    Filed: January 13, 2006
    Publication date: September 11, 2008
    Inventors: Ognjen Culic, Martina Bosnar, Nikola Marjanovic, Dubravko Jelic, Sulejman Alihodzic, Vanja Vela, Zorica Marusic-Istuk, Vesna Erakovic, Berislav Bosnjak, Boska Hrvacic, Marija Tomaskovic, Vanesa Munic, Vanesa Ivetic, Antun Hutinec, Goran Kragol, Marija Leljak
  • Derivatives of amino-ascorbic acid, the processes for their preparation and use
    Patent number: 5610181
    Abstract: The invention relates to the process for the preparation of new derivatives of amino-ascorbic acid, their acid and alkali salts, processes for preparation and action.According to this invention derivatives of amino-ascorbic acid are prepared by three types of reactions: 1. reductive alkylation of amino-ascorbic acid; 2. alkylation of primary and secondary amines with halogen-ascorbic acid and 3. acylation of amino-ascorbic acid.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: March 11, 1997
    Assignee: Pliva, farmaceutska, kemijska, prehrambena i kozmeticka industrija dionicko drustvo
    Inventors: Bo zidar Su skovi c, Vanja Vela, Mira Bun ci c
  • Derivatives of amino-ascorbic acid, the processes for their preparation and use
    Patent number: 5559251
    Abstract: The invention relates to the process for the preparation of new derivatives of amino-ascorbic acid, their acid and alkali salts, processes for preparation and action.According to this invention derivatives of amino-ascorbic acid are prepared by three types of reactions: 1. reductive alkylation of amino-ascorbic acid; 2. alkylation of primary and secondary amines with halogen-ascorbic acid and 3. acylation of amino-ascorbic acid.
    Type: Grant
    Filed: February 3, 1994
    Date of Patent: September 24, 1996
    Assignee: Pliva, farmaceutska
    Inventors: Bozidar Suskovic, Vanja Vela, Mira Buncic