Abstract: The invention describes a detection device that comprise nanostructures and which detection mechanism is based on the quantum confinement effects. The analyte species are sensed by measuring charge or/and energy transfer between the species and the nanostructures, which will be proportional to the overlap between the density of states distribution in the nanostructures and the density of states distribution in the targeted analyte species.

Abstract: The invention describes detection methods and devices that comprise nanostructures and which detection mechanism is based on the quantum confinement effects. The nanostructures are built to have specific energy levels designed to match the energy levels of the targeted analyte that is to be detected. The analyte species are sensed by measuring charge or/and energy transfer between the species and the nanostructures, which will be proportional to the overlap between the density of states distribution in the nanostructures and the density of states distribution in the targeted analyte species. Different molecular species have different electronic density of states, so the charge or/and energy transfer between the targeted analyte and detector nanostructures will occur only for specific analyte which has the same electronic density of states as the detectors nanostructure.