Patents by Inventor Varda Shoshan-Bar-Matz

Varda Shoshan-Bar-Matz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Photoreactive compound specifically binding to calcium binding proteins
    Patent number: 8034314
    Abstract: The present invention provides a photoreactive reagent that binds specifically to Ca2+-binding proteins, links to them covalently after photo-activation, and labels them. The novel reagent enables the characterization, purification, inhibition and screening of Ca2+-binding proteins, as well as the preparation of a new affinity chromatography matrix and a new protein biosensor. The invention also relates to the use of the reagent in inhibiting apoptosis and necrosis and in diagnosing a disorder associated with a defect in the function of a Ca2+-binding protein, and in the preparation of a medicament for treating such disorders.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: October 11, 2011
    Assignee: The National Institute for Biotechnology in the Negev Ltd.
    Inventors: Varda Shoshan-Bar-Matz, Adrian Israelson
  • Photoreactive Compound Specifically Binding to Calcium Binding Proteins
    Publication number: 20070298120
    Abstract: The present invention provides a photoreactive reagent that binds specifically to Ca2+-binding proteins, links to them covalently after photo-activation, and labels them. The novel reagent enables the characterization, purification, inhibition and screening of Ca2+-binding proteins, as well as the preparation of a new affinity chromatography matrix and a new protein biosensor. The invention also relates to the use of the reagent in inhibiting apoptosis and necrosis and in diagnosing a disorder associated with a defect in the function of a Ca2+-binding protein, and in the preparation of a medicament for treating such disorders.
    Type: Application
    Filed: February 17, 2005
    Publication date: December 27, 2007
    Inventors: Varda Shoshan-Bar-Matz, Adrian Israelson