Patents by Inventor Vasantha P. Rao

Vasantha P. Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating glaucoma and macular degeneration
    Patent number: 8669253
    Abstract: Inhibition of geranylgeranylation of Rho GTPases and heterotrimeric G-proteins in the aqueous outflow pathway increases aqueous humor outflow, possibly through the tissue relaxation, and through altered cell adhesive interactions and actin cytoskeletal organization in cells of the outflow pathway. In addition, such inhibition is useful for treating age-related macular degeneration. The GGTase-I enzyme is a molecular target for lowering increased ocular pressure in glaucoma patients.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: March 11, 2014
    Assignee: Duke University
    Inventors: Vasantha P. Rao, Patrick J. Casey, Peifeng Deng, Yuri K. Peterson